Reijo Lahti
reila@utu.fi +358 40 526 5670 Tykistökatu 6 Turku |
Publications 
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- Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase (2001) Heikinheimo P, Tuominen V, Ahonen AK, Teplyakov A, Cooperman BS, Baykov AA, Lahti R, Goldman A
(A1 Refereed original research article in a scientific journal) - Engineering a new magnesium binding site in the subunit contact region of Escherichia coli inorganic pyrophosphatase (2000)
- Биохимия / Biochemistry
(A1 Refereed original research article in a scientific journal) - Directed mutagenesis studies of the metal binding site at the subunit interface of Escherichia coli inorganic pyrophosphatase (1999)
- Journal of Biological Chemistry
(A1 Refereed original research article in a scientific journal) - Evolutionary aspects of inorganic pyrophosphatase (1999)
- FEBS Letters
(A1 Refereed original research article in a scientific journal) - Reciprocal effects of substitutions at the subunit interfaces in hexameric pyrophosphatase of Escherichia coli - Dimeric and monomeric forms of the enzyme (1999)
- Journal of Biological Chemistry
(A1 Refereed original research article in a scientific journal) - Cloning and expression of a unique inorganic pyrophosphatase from Bacillus subtilis: evidence for a new family of enzymes (1998)
- FEBS Letters
(A1 Refereed original research article in a scientific journal) - The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: Structural studies and mechanistic implications (1998) Tuominen V, Heikinheimo P, Kajander T, Torkkel T, Hyytia T, Kapyla J, Lahti R, Cooperman BS, Goldman A
(A1 Refereed original research article in a scientific journal) - Structural and functional consequences of substitutions at the tyrosine 55 lysine 104 hydrogen bond in Escherichia coli inorganic pyrophosphatase (1997) Fabrichniy IP, Kasho VN, Hyytia T, Salminen T, Halonen P, Dudarenkov VY, Heikinheimo P, Chernyak VY, Goldman A, Lahti R, Cooperman BS, Baykov AA
(A1 Refereed original research article in a scientific journal) - The three metal ion mechanism of inorganic pyrophosphatases (1997)
- Protein Engineering
(A1 Refereed original research article in a scientific journal) - A site-directed mutagenesis study of Saccharomyces cerevisiae pyrophosphatase - Functional conservation of the active site of soluble inorganic pyrophosphatases (1996)
- European Journal of Biochemistry
(A1 Refereed original research article in a scientific journal) - The structural basis for pyrophosphatase catalysis (1996)
- Structure
(A1 Refereed original research article in a scientific journal) - New crystal forms of Escherichia coli and Saccharomyces cerevisiae soluble inorganic pyrophosphatases (1995)
- Acta Crystallographica Section D: Biological Crystallography
(A1 Refereed original research article in a scientific journal) - Structure and function analysis of Escherichia coli inorganic pyrophosphatase: is a hydroxide ion the key to catalysis? (1995)
- Biochemistry
(A1 Refereed original research article in a scientific journal) - Characterization of the 5′ flanking region of the Escherichia coli ppa gene encoding inorganic pyrophosphatase: mutations in the ribosome-binding site decrease the level of ppa mRNA (1991)
- Journal of general microbiology
(A1 Refereed original research article in a scientific journal) - Genetic engineering of Escherichia coli inorganic pyrophosphatase
Tyr55 and Tyr141 are important for the structural integrity (1991)- European Journal of Biochemistry
(A1 Refereed original research article in a scientific journal) - A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity (1990) LAHTI R, POHJANOKSA K, PITKARANTA T, HEIKINHEIMO P, SALMINEN T, MEYER P, HEINONEN J
(A1 Refereed original research article in a scientific journal)
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