PhD, Adjunct Professor in Cancer Biology Kaisa Huhtinen - UTU Research Portal

Kaisa Huhtinen
PhD, Adjunct Professor in Cancer Biology

- Docent,
Faculty of Medicine (University of Turku)

kaisa.huhtinen@utu.fi

+358 29 450 2645

+358 50 572 6733

Kiinamyllynkatu 10

Turku

Office: D5038

ORCID identifier: https://orcid.org/0000-0001-9685-5246

ResearchGate_Kaisa_Huhtinen

Areas of expertise

Ovarian cancer; personalized medicine; early diagnostics; prediction; prognosis; biomarker; genomics; drug target; interdicipline research;

Biography

Research

Publications

3 of 4

A cancer-specific detection of serum CA125 improves differential diagnosis of epithelial ovarian cancer from benign conditions. (2018)
- Clinical Cancer Research
Huhtinen K, Gidwani K, Kekki H, Hynninen J, Salminen L, Perheentupa A, Poutanen M, Auranen A, Grenman S, Lamminmaki U, Carpen O, Pettersson K
(Other publication)
A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients (2018)
- Clinical Cancer ResearchJournal of Mass Spectrometry
Tumiati M, Hietanen S, Hynninen J, Pietilä E, Färkkilä A, Kaipio K, Roering P, Huhtinen K, Alkodsi A, Li Y, Lehtonen R, Erkan EP, Tuominen MM, Lehti K, Hautaniemi SK, Grénman S, Vähärautio A, Carpén O, Kauppi L
(A1 Refereed original research article in a scientific journal)
CA125 glycoform assay improves the performance of conventional CA125 in the diagnostics of epithelial ovarian cancerEndometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels. (2018)
- International Journal of Gynecological CancerJournal of Clinical Endocrinology and Metabolism
Salminen L, Gidwani K, Rolfsen AL, Nadeem N, Bolstad N, Dorum A, Grenman S, Hietanen S, Perheentupa A, Poutanen M, Carpen O, Lamminmaki U, Pettersson K, Hynninen J, Huhtinen K
(Other publication)
High-throughput screening of new potential targets for high-grade serous ovarian cancer treatment (2018)
- Clinical Cancer Research
Dai J, Erkan EP, Zhang KY, Kaipio K, Lamminen T, Huhtinen K, Hynninen J, Grenman S, Carpen OM, Hautaniemi S, Vaharautio A
(Other publication)
Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis (2018)
- Human Reproduction
Heinosalo T, Gabriel M, Kallio L, Adhikari P, Huhtinen K, Laajala TD, Kaikkonen E, Mehmood A, Suvitie P, Kujari H, Aittokallio T, Perheentupa A, Poutanen M
(A1 Refereed original research article in a scientific journal)
The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer (2018)
- Oncology
Kemiläinen H., Huhtinen K., Auranen A., Carpén O., Strauss L., Poutanen M.
(A1 Refereed original research article in a scientific journal)
DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer (2017)
- Scientific Reports
Riikka J. Lund, Kaisa Huhtinen, Jussi Salmi, Juha Rantala, Elizabeth V. Nguyen, Robert Moulder, David R. Goodlett, Riitta Lahesmaa, Olli Carpén
(A1 Refereed original research article in a scientific journal)
Hyper-phosphorylation of Sequestosome-1 Distinguishes Resistance to Cisplatin in Patient Derived High Grade Serous Ovarian Cancer Cells (2017)
- Molecular and Cellular Proteomics
Nguyen Elizabeth V, Huhtinen Kaisa, Goo Young Ah, Kaipio Katja, Andersson Noora, Rantanen Ville, Hynninen Johanna, Lahesmaa Riitta, Carpen Olli, Goodlett David R
(A1 Refereed original research article in a scientific journal)
Uusi lektiini-avusteinen määrityskonsepti parantamaan CA-125-kasvainmerkkiaineen munasarjasyöpäspesifisyyttä (2017)
- Kliin lab
Kekki H, Gidwani K, Huhtinen K, Hynninen J, Pettersson K
(D1 Article in a professional journal)
A Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign Sources (2016)
- Clinical Chemistry
Gidwani Kamlesh, Huhtinen Kaisa, Kekki Henna, van Vliet Sandra, Hynninen Johanna, Koivuviita Niina, Perheentupa Antti, Poutanen Matti, Auranen Annika, Grenman Seija, Lamminmaki Urpo, Carpen Olli, van Kooyk Yvette, Pettersson Kim
(A1 Refereed original research article in a scientific journal)
Characterization of ascites and tumor-derived ovarian cancer stem-like cells (2016)
- Clinical Cancer Research
Kaipio K, Chen P, Huhtinen K, Mikkonen P, Ostling P, Mpindi JP, Lehtinen L, Roering P, Korpela T, Wennerberg K, Yadav B, Aittokallio T, Kulesskiy E, Hynninen J, Auranen A, Grenman S, Hautaniemi S, Carpen O
(Other publication)
Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells' sensitivity to paclitaxel (2016)
- Oncotarget
Mahesh Tambe, Sofia Pruikkonen, Jenni Mäki-Jouppila, Ping Chen,
Bente Vilming Elgaaen, Anne Hege Straume, Kaisa Huhtinen, Olli Cárpen, Per
Eystein Lønning, Ben Davidson, Sampsa Hautaniemi, Marko J. Kallio
(A1 Refereed original research article in a scientific journal)
Identification of Prognostic Groups in High-Grade Serous Ovarian Cancer Treated with Platinum-Taxane Chemotherapy (2015)
- Cancer Research
Chen P, Huhtinen K, Kaipio K, Mikkonen P, Aittomaki V, Lindell R, Hynninen J, Auranen A, Grenman S, Lehtonen R, Carpen O, Hautaniemi S
(A1 Refereed original research article in a scientific journal)
High-grade serous ovarian cancer subtyping identifies pathways for targeted therapy (2014)
- European Journal of Cancer
Huhtinen K, Chen P, Mikkonen P, Kaipio K, Aittomaki V, Lindell R, Auranen A, Lehtonen R, Hautaniemi S, Carpen O
(Other publication)
Intra-Tissue Steroid Profiling Indicates Differential Progesterone and Testosterone Metabolism in the Endometrium and Endometriosis Lesions (2014)
- Journal of Clinical Endocrinology and Metabolism
Huhtinen K, Saloniemi-Heinonen T, Keski-Rahkonen P, Desai R, Laajala D, Ståhle M, Häkkinen M, Laajala D, Suvitie P, Awosanya M, Aittokallio T, Handelsman D, Auriola S, Perheentupa A, Poutanen M.
(A1 Refereed original research article in a scientific journal)
Ovarian Endometriosis Signatures Established through Discovery and Directed Mass Spectrometry Analysis (2014)
- Journal of Proteome Research
Vehmas AP, Muth-Pawlak D, Huhtinen K, Saloniemi-Heinonen T, Jaakkola K, Laajala TD, Kaprio H, Suvitie PA, Aittokallio T, Siitari H, Perheentupa A, Poutanen M, Corthals GL
(A1 Refereed original research article in a scientific journal)
Serum concentrations of HE4 change little during in vitro fertilization. (2014)
- Acta Obstetricia et Gynecologica Scandinavica
Hallamaa M, Huhtinen K, Suvitie P, Perheentupa A
(A1 Refereed original research article in a scientific journal)
Characterization of primary high-grade serous ovarian cancer cell lines: Cell line and growth condition specific differences in stem cell marker expression and high-throughput drug screening (2013)
- Clinical Cancer Research
Roering P, Mikkonen P, Kaipio K, Huhtinen K, Hynninen J, Auranen A, Kulesskiy E, Yadav B, Aittokallio T, Grenman S, Wennerberg K, Carpen O
(Other publication)
LC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization (2013)
Keski-Rahkonen P, Huhtinen K, Desai R, Harwood DT, Handelsman DJ, Poutanen M, Auriola S
(A1 Refereed original research article in a scientific journal)
(2012)
Huhtinen K, Desai R, Ståhle M, Salminen A, Handelsman DJ, Perheentupa A, Poutanen M.
(A1 Refereed original research article in a scientific journal)