Tiina Laitala
tilale@utu.fi +358 29 450 4619 +358 50 477 9873 Kiinamyllynkatu 10 Turku |
mTBI; microRNA; imaging; concussion; neuroanatomy; visuomotor research; tissue trauma healing; skeletal biology; sports trauma
Our research focuses on the mechanisms involved in short regulatory RNA physiology. These molecules (siRNAs, shRNAs, microRNAs) modulate gene expression, thus affecting not only differentiation and developmental maturation of cells and organ systems, but also tissue healing after trauma.
- Neuroanatomy
- Human gross anatomy
- Histology
- Cell biology
- Sports trauma
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- Unsatisfactory gene transfer into bone-resorbing osteoclasts with liposomal transfection systems (2005)
- Journal of Negative Results in BioMedicine
- Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption (2001) Zhao HB, Laitala-Leinonen T, Parikka V, Vaananen HK
- Decreased bone resorption, osteoclast differentiation, and expression of vacuolar H+-ATPase in antisense DNA-treated mouse metacarpal and calvaria cultures ex vivo (1999)
- Antisense and Nucleic Acid Drug Development
- Inhibition of intravacuolar acidification by antisense RNA decreases osteoclast differentiation and bone resorption in vitro (1999)
- Journal of Cell Science
- Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+ (1998)
- Experimental Cell Research
UTU Research Portal