Tiina Laitala
tilale@utu.fi +358 29 450 4619 +358 50 477 9873 Kiinamyllynkatu 10 Turku |
mTBI; microRNA; imaging; concussion; neuroanatomy; visuomotor research; tissue trauma healing; skeletal biology; sports trauma
Our research focuses on the mechanisms involved in short regulatory RNA physiology. These molecules (siRNAs, shRNAs, microRNAs) modulate gene expression, thus affecting not only differentiation and developmental maturation of cells and organ systems, but also tissue healing after trauma.
- Neuroanatomy
- Human gross anatomy
- Histology
- Cell biology
- Sports trauma
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- Solid-Supported NOTA and DOTA Chelators Useful for the Synthesis of 3 '-Radiometalated Oligonucleotides (2012)
- Bioconjugate Chemistry
- Micro-RNAs regulate the differentiation of human bone marrow-derived MSCs (2011)
- BONE
- Receptor tyrosine kinase inhibition causes simultaneous bone loss and excess bone formation within growing bone in rats. (2011)
- Toxicology and Applied Pharmacology
- Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes (2011)
- Osteoarthritis and Cartilage
- Tyrosine kinase inhibition by imatinib mesylate interferes with bone growth and remodellation in rats (2011)
- BONE
- Degradation of hydroxyapatite in vivo and in vitro requires osteoclastic sodium-bicarbonate co-transporter NBCn1 (2010)
- Matrix Biology
- Impact of stromal cell composition on BMP-induced chondrogenic differentiation of mouse bone marrow derived mesenchymal cells (2008)
- Experimental Cell Research
- MicroRNAs regulate osteogenesis and chondrogenesis of mouse bone marrow stromal cells (2008)
- Cellular Oncology [continued by Analytical Cellular Pathology]
- MicroRNAs Regulate Osteogenesis and Chondrogenesis of Mouse Bone Marrow Stromal Cells (2008)
- Gene Regulation and Systems Biology
- Osteoclast lineage and function (2008)
- Archives of Biochemistry and Biophysics
- Recombinant VSV G proteins reveal a novel raft-dependent endocytic pathway in resorbing osteoclasts (2008)
- Experimental Cell Research
- Electroneutral sodium/bicarbonate cotransporter NBCn1 is expressed in rat osteoclast ruffled border membrane (2007)
- Journal of Bone and Mineral Research
- In silico promoter analysis of vacuolar proton pump subunits (2007)
- Calcified Tissue International
- Membrane-bound carbonic anhydrases in osteoclasts (2007) Riihonen R, Supuran CT, Parkkila S, Pastorekova S, Vaananen HK, Laitala-Leinonen T
- RNA interference tolerates 2 '-fluoro modifications at the Argonaute2 cleavage site (2007)
- Chemistry and Biodiversity
- Sequence and TLR9 independent increase of TRACP expression by antisense DNA and siRNA molecules (2007)
- Biochemical and Biophysical Research Communications
- Cystatin B as an intracellular modulator of bone resorption (2006)
- Matrix Biology
- Toll-like receptor 9 knockout mice exhibit age and gender specific differences in regulation of bone modeling. (2006)
- Journal of Bone and Mineral Research
- Inhibition of the osteoclast V-ATPase by small interfering RNAs (2005)
- FEBS Letters
- Osteoclast function relies on raft-dependent vesicle trafficking between the ruffled border and the functional secretory domain (2005) Mulari MTK, Nars M, Kaisto T, Metsikko K, Laitala-Leinonen T, Vaananen K
UTU Research Portal