Tiina Laitala
tilale@utu.fi +358 29 450 4619 +358 50 477 9873 Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0002-6249-5710 |
Areas of expertise
mTBI; microRNA; imaging; concussion; neuroanatomy; visuomotor research; tissue trauma healing; skeletal biology; sports trauma
mTBI; microRNA; imaging; concussion; neuroanatomy; visuomotor research; tissue trauma healing; skeletal biology; sports trauma
Research
Our research focuses on the mechanisms involved in short regulatory RNA physiology. These molecules (siRNAs, shRNAs, microRNAs) modulate gene expression, thus affecting not only differentiation and developmental maturation of cells and organ systems, but also tissue healing after trauma.
Teaching
- Neuroanatomy
- Human gross anatomy
- Histology
- Cell biology
- Sports trauma
Publications
- Unsatisfactory gene transfer into bone-resorbing osteoclasts with liposomal transfection systems (2005)
- Journal of Negative Results in BioMedicine
(A1 Refereed original research article in a scientific journal) - Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption (2001) Zhao HB, Laitala-Leinonen T, Parikka V, Vaananen HK
(A1 Refereed original research article in a scientific journal) - Decreased bone resorption, osteoclast differentiation, and expression of vacuolar H+-ATPase in antisense DNA-treated mouse metacarpal and calvaria cultures ex vivo (1999)
- Antisense and Nucleic Acid Drug Development
(A1 Refereed original research article in a scientific journal) - Inhibition of intravacuolar acidification by antisense RNA decreases osteoclast differentiation and bone resorption in vitro (1999)
- Journal of Cell Science
(A1 Refereed original research article in a scientific journal) - Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+ (1998)
- Experimental Cell Research
(A1 Refereed original research article in a scientific journal)