Tero Aittokallio
PhD
teanai@utu.fi Tykistökatu 6 A Turku ORCID identifier: https://orcid.org/orcid.org/0000-0002-0886-9769 |
Tero Aittokallio received his PhD in Applied Mathematics from the University of Turku in 2001, under the supervision of Prof. Mats Gyllenberg. He then did his post-doctoral training in the Systems Biology Lab at the Institut Pasteur (2006-2007), with Dr. Benno Schwikowski, where he focused on network biology applications using high-throughput experimental assays and network analysis tools such as Cytoscape. In 2007, Dr. Aittokallio launched his independent career as a principal investigator in the Turku Biomathematics Research Group, where he received a five-year appointment as an Academy of Finland Research Fellow (2007-2012). Tero Aittokallio joined Institute for Molecular Medicine Finland (FIMM) as EMBL Group Leader in the fall of 2011, and was selected as Professor of Statistics and Applied Mathematics at University of Turku in 2015.
Aittokallio's research group focuses on developing and applying integrated computational-experimental approaches to tackle biomedical questions, such as how genes function as interaction networks to carry out and regulate cellular processes, how alterations in these networks contribute to complex traits, such as human diseases, and where and how in the disease network one should target to optimally inhibit the disease phenotypes, such as tumor growth.
Computational statistics.
Scientific computing.
- Early suppression of immune response pathways characterizes children with prediabetes in genome-wide gene expression profilingGenetic Variants and Their Interactions in the Prediction of Increased Pre-Clinical Carotid Atherosclerosis: The Cardiovascular Risk in Young Finns StudyElectrophoretic signal comparison applied to mRNA differential display analysis (2010)
- Journal of AutoimmunityPLoS Genetics
(A1 Refereed original research article in a scientific journal) - Genome-wide Profiling of Interleukin-4 and STAT6 Transcription Factor Regulation of Human Th2 Cell Programming (2010)
(A1 Refereed original research article in a scientific journal) - Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices (2010)
- ImmunityEuropean Respiratory Journal
(A1 Refereed original research article in a scientific journal) - (2010)
- PLoS ONEEuropean Journal of Immunology
(A1 Refereed original research article in a scientific journal) - (2010)
- Photosynthesis Research
(A1 Refereed original research article in a scientific journal) - Novel Insights Into the Gene Regulatory Networks Regulating Human T Helper (TH) cell DifferentiationQuantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation (2010)
- Scandinavian Journal of ImmunologyMolecular and Cellular Proteomics
(Other publication) - A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments (2010)
(A1 Refereed original research article in a scientific journal) - (2009)
- BMC Genomics
(A1 Refereed original research article in a scientific journal) - Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studiesTranscutaneous carbon dioxide profile during sleep reveals metabolic risk factors in post-menopausal females (2009)
- Genome Biology
(A1 Refereed original research article in a scientific journal) - (2009)
(A1 Refereed original research article in a scientific journal) - Reproducibility-optimized test statistic for ranking genes in microarray studies (2008)
- IEEE/ACM Transactions on Computational Biology and Bioinformatics
(A1 Refereed original research article in a scientific journal) - Computer-assisted identification of multitrace electrophoretic patterns in differential display experiments (2007)
- ELECTROPHORESIS
(A1 Refereed original research article in a scientific journal) - Inspiratory flow shape clustering: An automated method to monitor upper airway performance during sleep (2007)
- Computer Methods and Programs in Biomedicine
(A1 Refereed original research article in a scientific journal) - Improving identification of differentially expressed genes by integrative analysis of Affymetrix and Illumina arrays. (2006)
- OMICS
(A1 Refereed original research article in a scientific journal) - A comparative evaluation of software for the analysis of liquid chromatography-tandem mass spectrometry data from isotope coded affinity tag experiments. (2005) Moulder R, Filen JJ, Salmi J, Katajamaa M, Nevalainen OS, Oresic M, Aittokallio T, Lahesmaa R, Nyman TA
(A1 Refereed original research article in a scientific journal) - (2003)
- Biotechniques
(A1 Refereed original research article in a scientific journal) - (2003) Lund R, Aittokallio T, Nevalainen O, Lahesmaa R.
(A1 Refereed original research article in a scientific journal) - Kinetics and STAT4- or STAT6-mediated regulation of genes involved in lymphocyte polarization to Th1 and Th2 cells. (2003)
(A1 Refereed original research article in a scientific journal)



