Tero Aittokallio
PhD
teanai@utu.fi Tykistökatu 6 A Turku ORCID identifier: https://orcid.org/orcid.org/0000-0002-0886-9769 |
Tero Aittokallio received his PhD in Applied Mathematics from the University of Turku in 2001, under the supervision of Prof. Mats Gyllenberg. He then did his post-doctoral training in the Systems Biology Lab at the Institut Pasteur (2006-2007), with Dr. Benno Schwikowski, where he focused on network biology applications using high-throughput experimental assays and network analysis tools such as Cytoscape. In 2007, Dr. Aittokallio launched his independent career as a principal investigator in the Turku Biomathematics Research Group, where he received a five-year appointment as an Academy of Finland Research Fellow (2007-2012). Tero Aittokallio joined Institute for Molecular Medicine Finland (FIMM) as EMBL Group Leader in the fall of 2011, and was selected as Professor of Statistics and Applied Mathematics at University of Turku in 2015.
Aittokallio's research group focuses on developing and applying integrated computational-experimental approaches to tackle biomedical questions, such as how genes function as interaction networks to carry out and regulate cellular processes, how alterations in these networks contribute to complex traits, such as human diseases, and where and how in the disease network one should target to optimally inhibit the disease phenotypes, such as tumor growth.
Computational statistics.
Scientific computing.
- Genome-Wide Scoring of Positive and Negative Epistasis through Decomposition of Quantitative Genetic Interaction Fitness Matrices (2010)
- PLoS ONE
(A1 Refereed original research article in a scientific journal) - Mahalanobis distance screening of Arabidopsis mutants with chlorophyll fluorescence (2010)
- Photosynthesis Research
(A1 Refereed original research article in a scientific journal) - Novel Insights Into the Gene Regulatory Networks Regulating Human T Helper (TH) cell Differentiation (2010)
- Scandinavian Journal of Immunology
(Other publication) - Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation (2010)
- Molecular and Cellular Proteomics
(A1 Refereed original research article in a scientific journal) - A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments (2009)
- BMC Genomics
(A1 Refereed original research article in a scientific journal) - Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studies (2009)
- Genome Biology
(A1 Refereed original research article in a scientific journal) - Transcutaneous carbon dioxide profile during sleep reveals metabolic risk factors in post-menopausal females (2009)
- European Respiratory Journal
(A1 Refereed original research article in a scientific journal) - Reproducibility-optimized test statistic for ranking genes in microarray studies (2008)
- IEEE/ACM Transactions on Computational Biology and Bioinformatics
(A1 Refereed original research article in a scientific journal) - Computer-assisted identification of multitrace electrophoretic patterns in differential display experiments (2007)
- ELECTROPHORESIS
(A1 Refereed original research article in a scientific journal) - Inspiratory flow shape clustering: An automated method to monitor upper airway performance during sleep (2007)
- Computer Methods and Programs in Biomedicine
(A1 Refereed original research article in a scientific journal) - Improving identification of differentially expressed genes by integrative analysis of Affymetrix and Illumina arrays. (2006)
- OMICS
(A1 Refereed original research article in a scientific journal) - A comparative evaluation of software for the analysis of liquid chromatography-tandem mass spectrometry data from isotope coded affinity tag experiments. (2005) Moulder R, Filen JJ, Salmi J, Katajamaa M, Nevalainen OS, Oresic M, Aittokallio T, Lahesmaa R, Nyman TA
(A1 Refereed original research article in a scientific journal) - Electrophoretic signal comparison applied to mRNA differential display analysis (2003)
- Biotechniques
(A1 Refereed original research article in a scientific journal) - Identification of novel genes regulated by IL-12, IL-4, or TGF-beta during the early polarization of CD4+ lymphocytes. (2003) Lund R, Aittokallio T, Nevalainen O, Lahesmaa R.
(A1 Refereed original research article in a scientific journal) - Kinetics and STAT4- or STAT6-mediated regulation of genes involved in lymphocyte polarization to Th1 and Th2 cells. (2003)
- European Journal of Immunology
(A1 Refereed original research article in a scientific journal)