Pekka Taimen
MD, PhD
pepeta@utu.fi +358 29 450 4524 +358 50 431 1353 Kiinamyllynkatu 10 Turku Office: D5019 ORCID identifier: https://orcid.org/0000-0001-8849-4604 Official web page of research group |
pathology; histology; cell biology; prostate cancer, bladder cancer, cardiomyopathy, nuclear lamin
Pekka Taimen received his MD degree from the University of Turku in 2001 and defended his thesis at the Department of Pathology, University of Turku in 2004. In 2008-2009 PT worked as a postdoctoral fellow in the laboratory of Prof. Robert D. Goldman, Northwestern University Medical School, Chicago. Postdoctoral studies focusing on nuclear intermediate filament proteins called lamins were further continued as a junior group leader after returning back to Turku in early 2010. In 2011 PT received a specialist degree in Pathology and since then he has worked as a part-time specialist at the Pathology Division, Turku University Hospital with special focus on uropathology. From 2012 PT has worked as a Clinical lecturer in Pathology and between 2015-2019 as a part-time Academy of Finland Clinical Researcher. PT was appointed as a tenure track Assistant Professor of Molecular Pathology in January 2019 and an Associate Professor in August 2020. In January 2022, PT was appointed as a Professor of Molecular Pathology and he currently serves as the head of the pathology unit at the Faculty of Medicine, University of Turku.
Professor Pekka Taimen has 20 years of experience in cell and molecular biology as well as in translational research. The main focus of his research group is on human diseases caused by lamin mutations, such as cardiomyopathies and premature aging syndrome. More recently, PT has also actively worked on prostate and bladder cancer related projects including novel biomarkers, biobanking, patient derived cell lines and improved imaging techniques utilizing digital pathology and machine learning approaches.
Pekka Taimen has more than 10 years of experience in teaching medical students at the Institute of Biomedicine, University of Turku. He has served first as a university teacher and from 2012 as a clinical lecturer. In 2015 PT received the Lecturer of the Year award in the Faculty of Medicine.
- A Prospective Comparison of 18F-prostate-specific Membrane Antigen-1007 Positron Emission Tomography Computed Tomography, Whole-body 1.5 T Magnetic Resonance Imaging with Diffusion-weighted Imaging, and Single-photon Emission Computed Tomography/Computed Tomography with Traditional Imaging in Primary Distant Metastasis Staging of Prostate Cancer (PROSTAGE) (2021)
- European Urology Oncology
(A1 Refereed original research article in a scientific journal) - Combined Use of Prostate-specific Antigen Density and Magnetic Resonance Imaging for Prostate Biopsy Decision Planning: A Retrospective Multi-institutional Study Using the Prostate Magnetic Resonance Imaging Outcome Database (PROMOD). (2021)
- European Urology Oncology
(A1 Refereed original research article in a scientific journal) - Computer extracted gland features from H&E predicts prostate cancer recurrence comparably to a genomic companion diagnostic test: a large multi-site study (2021)
- npj Precision Oncology
(A1 Refereed original research article in a scientific journal) - How to read biparametric MRI in men with a clinical suspicious of prostate cancer: Pictorial review for beginners with public access to imaging, clinical and histopathological database (2021)
- Acta Radiologica Open
(A2 Refereed review article in a scientific journal ) - Intravenous Interferon-beta 1a for the Treatment of Ischemia-Reperfusion Injury in Acute Myocardial Infarct in Pigs (2021)
- Heart Surgery Forum
(A1 Refereed original research article in a scientific journal) - Molekyylipatologia osana syöpäpotilaan hoitoa : patologin uusi rooli (2021)
- Duodecim
(D1 Article in a professional journal) - Negative Predictive Value of Biparametric Prostate Magnetic Resonance Imaging in Excluding Significant Prostate Cancer: A Pooled Data Analysis Based on Clinical Data from Four Prospective, Registered Studies (2021)
- European Urology Focus
(A1 Refereed original research article in a scientific journal) - Prediction of neo-adjuvant chemotherapy response in bladder cancer: the impact of clinical parameters and routine biomarkers (2021)
- Scandinavian Journal of Urology
(A1 Refereed original research article in a scientific journal) - Prognostic and predictive value of ALDH1, SOX2 and SSEA-4 in bladder cancer (2021)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Prospective comparison of 18F-PSMA-1007 PET/CT, whole-body MRI and CT in primary nodal staging of unfavourable intermediate- and high-risk prostate cancer (2021)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - Response to the Letter to the Editor: Prospective comparison of 18F-PSMA-1007 PET/CT, whole-body MRI and CT in primary nodal staging of unfavourable intermediate- and high-risk prostate cancer (2021)
- European Journal of Nuclear Medicine and Molecular Imaging
(B1 Non-refereed article in a scientific journal) - Test-retest repeatability of a deep learning architecture in detecting and segmenting clinically significant prostate cancer on apparent diffusion coefficient (ADC) maps (2021)
- European Radiology
(A1 Refereed original research article in a scientific journal) - Visual MRI T-category versus VI-RADS evaluation from multiparametric MRI in the detection of muscle-invasion in patients with suspected bladder cancer: single centre registered clinical trial (MIB-trial) (2021)
- Scandinavian Journal of Urology
(A1 Refereed original research article in a scientific journal) - Acute and subacute prostate MRI findings after MRI-guided transurethral ultrasound ablation of prostate cancer (2020)
- Acta Radiologica
(A1 Refereed original research article in a scientific journal) - Added value of systematic biopsy in men with a clinical suspicion of prostate cancer undergoing biparametric MRI-targeted biopsy: multi-institutional external validation study (2020)
- World Journal of Urology
(A1 Refereed original research article in a scientific journal) - Critical evaluation of the subcutaneous engraftments of hormone naïve primary prostate cancer (2020)
- Translational andrology and urology
(A1 Refereed original research article in a scientific journal) - Folate Receptor β Targeted PET Imaging of Macrophages in Autoimmune Myocarditis (2020)
- Journal of Nuclear Medicine
(A1 Refereed original research article in a scientific journal) - High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study (2020)
- Neoplasia
(A1 Refereed original research article in a scientific journal) - Impact of biparametric prebiopsy prostate magnetic resonance imaging on the diagnostics of clinically significant prostate cancer in biopsy naïve men (2020)
- Scandinavian Journal of Urology
(A1 Refereed original research article in a scientific journal) - Interaction between prostate cancer cells and prostate fibroblasts promotes accumulation and proteolytic processing of basement membrane proteins (2020)
- Prostate
(A1 Refereed original research article in a scientific journal)