Juhani Knuuti
MD, professor, Turku PET Centre
jknuuti@utu.fi +358 29 450 2345 +358 50 059 2998 Kiinamyllynkatu 4-8 Turku |
Cardiovascular diseases, imaging
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
- (2007)
- Journal of Cerebral Blood Flow and Metabolism
- Coronary artery flow velocity profile measured by transthoracic Doppler echocardiography predicts myocardial viability after acute myocardial infarction (2007)
- Heart
- (2007)
- Vascular PharmacologyScandinavian Journal of Clinical and Laboratory Investigation
- Diagnostic and clinical perspectives of fusion imaging in cardiology: is the total greater than the sum of its parts? (2007)
- Heart
- Dual gating method for eliminating motion-related inaccuracies in cardiac PET (2007)
- IEEE Nuclear Science Symposium conference recordJournal of Nuclear Cardiology
- (2007)
- DiabetologiaEuropean Journal of Nuclear Medicine and Molecular Imaging
- (2007)
- CirculationGastroenterology
- (2007)
- Scandinavian Journal of Clinical and Laboratory Investigation
- Imaging of the failing heart (2007)
- Scandinavian Journal of Surgery
- Improvement of myocardial blood flow by lipid-lowering therapy with pravastatin is modulated by apolipoprotein E genotype (2007)
- Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease (2007)
- Metabolism
- Myocardial energetics and efficiency - Current status of the noninvasive approach (2007)
- Circulation
- Myocardial perfusion, oxidative metabolism, and free fatty acid uptake in patients with hypertrophic cardiomyopathy attributable to the Asp175Asn mutation in the alpha-tropomyosin gene: A positron emission tomography study (2007)
- Performance of the new generation of whole-body PET/CT scanners: Discovery STE and discovery VCT (2007)
- Quantification of liver glucose metabolism by positron emission tomography: Validation study in pigs (2007)
- Response to letters regarding article, "free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure" (2007) Tuunanen H, Naum A, Nagren K, Nuutila P, Iozzo P, Ukkonen H, Knuuti J, Engblom E, Airaksinen EJ, Hesse B, Opie LH
- Simultaneous evaluation of myocardial blood flow, cardiac function and lung water content using [O-15]H2O and positron emission tomography (2007)
- European Journal of Nuclear Medicine and Molecular Imaging
- The failing heart (2007) Knaapen P, Knuuti J, van Rossum AC
- Uptake of 11C-PK11195, a marker of inflammatory cells, into atherosclerotic plaques in mice (2007)
- Atherosclerosis -Amsterdam- Supplement-
- 68Ga-labelled peptide inhibitor of vascular adhesion protein-1/semicarbazide sensitive amine oxidase as potential PET tracer for inflammation imaging (2006)
- European Journal of Nuclear Medicine and Molecular Imaging



