MD, professor, Turku PET Centre Juhani Knuuti - UTU Research Portal

Juhani Knuuti
MD, professor, Turku PET Centre

- Director,
- Professor,
Turku PET Centre (Independent units)
- ,
InFLAMES Flagship (Faculty of Medicine)

jknuuti@utu.fi

+358 29 450 2345

+358 50 059 2998

Kiinamyllynkatu 4-8

Turku

: https://orcid.org/0000-0003-3156-9593

CV J Knuuti 5th February 2021_signed.pdf

Cardiovascular diseases, imaging

Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.

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Fatty Acid Metabolism in the Liver, Measured by Positron Emission Tomography, Is Increased in Obese Individuals (2010)
- Gastroenterology
Iozzo P, Bucci M, Roivainen A, Nagren K, Jarvisalo MJ, Kiss J, Guiducci L, Fielding B, Naum AG, Borra R, Virtanen K, Savunen T, Salvadori PA, Ferrannini E, Knuuti J, Nuutila P
Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) (2010)
- European Journal of Cardio-Thoracic Surgery
Wijns W, Kohl P, Danchin N, Di Mario C, Falk V, Folliguet T, Garg S, Huber K, James S, Knuuti J, Lopez-Sendon J, Marco J, Menicanti L, Ostojic M, Piepoli MF, Pirlet C, Pomar JL, Reifart N, Ribichini FL, Schalij MJ, Sergeant P, Serruys PW, Silber S, Sousa Uva M, Taggart D, ESC Committee for Practice Guidelines Vahanian A, Auricchio A, Bax J, Ceconi C, Dean V, Fiilippatos G, Fuck-Brentano C, Hobbs R, Kearney P, McDonagh T, Popescu BA, Reiner Z, Sechtem U, Sirnes, PA Tendera M, Vardas PE, Widimsky P, EACTS Clinical Guidelines Committee Kohl P, Alfieri O Dunning J, Elia S, Kappetein P, Lockowandt U, Sarris G, Vouche P, Kearney P, von Segesser L, Agewall S, Aladashivili A, Alexopoulos D, Antunes MJ, Atalar E, Brutel de la Riviere A, Doganov A, Eha J, Fajadet J, Ferreira R, Garot J, Halcox J, Hasin Y, Janssens S, Kervinen K, Laufer G, Legrand G, Nashef SA, Neumann FJ, Niemela K, Nihoyannopoulos P, Noc M, Piek JJ, Pirk J, Rozenman Y, Sabate M, Starc R, Thielmann M, Wheatley DJ, Windecker S, Zembala M
Hybrid Imaging: PET-CT and SPECT-CT (2010) The ESC Textbook of Cardiovascular Imaging Knuuti J, Kaufmann PA
ICA Based Automatic Segmentation of Dynamic (H2O)-O-15 Cardiac PET Images (2010)
- IEEE Transactions on Information Technology in Biomedicine
Margadan-Mendez M, Juslin A, Nesterov SV, Kalliokoski K, Knuuti J, Ruotsalainen U
Imaging of Viability using PET (2010) Clinical Nuclear Cardiology: State of the Art and Future Directions Knuuti J, Di Carli M
Integrated anatomy and viability assessment PET-CT (2010)
- Eurointervention
Saraste A, Ukkonen H, Kajander S, Knuuti J
Metabolic imaging in myocardial ischemia and heart failure (2010)
- Quarterly Journal of Nuclear Medicine and Molecular Imaging
Knuuti J, Tuunanen H
Myocardial perfusion SPECT and PET (2010) Cardiovascular Multimodal Image-Guided Diagnosis And Therapy Carlsson M, Knuuti J
New clinical perspectives from imaging technologies for diagnosis and management of coronary artery disease (2010) Treatment Strategies - Cardiology; ESC Congress , Tukholma Knuuti J, Saraste A
Perfusion heterogeneity does not explain excess muscle oxygen uptake during variable intensity exercise (2010)
- Clinical Physiology and Functional Imaging
Laaksonen MS, Bjorklund G, Heinonen I, Kemppainen J, Knuuti J, Kyrolainen H, Kalliokoski KK
Regulation of human skeletal muscle perfusion and its heterogeneity during exercise in moderate hypoxia (2010)
- AJP - Regulatory, Integrative and Comparative Physiology
Heinonen IH, Kemppainen J, Kaskinoro K, Peltonen JE, Borra R, Lindroos M, Oikonen V, Nuutila P, Knuuti J, Boushel R, Kalliokoski KK
The ESC Textbook of Cardiovascular Imaging (2010) Zamorano JL, Bax JJ, Rademakers FE, Knuuti J
The Regulation Of Subcutaneous Adipose Tissue Blood Flow During Exercise In Humans (2010)
- Medicine and Science in Sports and Exercise
Heinonen I, Bucci M, Kemppainen J, Knuuti J, Nuutila P, Kalliokoski K
Uptake of (11)C-Choline in Mouse Atherosclerotic Plaques (2010)
- Journal of Nuclear Medicine
Laitinen IEK, Luoto P, Nagren K, Marjamaki PM, Silvola JMU, Hellberg S, Laine VJO, Yla-Herttuala S, Knuuti J, Roivainen A
68Ga-DOTA-RGD peptide: Biodistribution and binding into atherosclerotic plaques in mice (2009)
- European Journal of Nuclear Medicine and Molecular Imaging
Leppänen P., Laine J., Knuuti J., Ylä-Herttula S., Roivainen A., Haukkala J., Laitinen I., Luoto P., Iveson P., Wilson I., Karlsen H., Cuthbertson A.
Cardiovascular drug development using radiopharmaceuticals (2009)
- Current Pharmaceutical Design
Ukkonen H., Yoshinaga K., DaSilva J.N., Beanlands R.S.B., Knuuti J.
Comparison of current density viability imaging at rest with FDG-PET in patients after myocardial infarction (2009)
- Computerized Medical Imaging and Graphics
Lauerma K., Nenonen J., Mäkijärvi M., Knuuti J., Katila T., Toivonen L., Goernig M., Haueisen J., Schreiber J., Leder U., Hänninen H., Mäkelä T., Takala P.
Contribution of glucose tolerance and gender to cardiac adiposity (2009)
- Journal of Clinical Endocrinology and Metabolism
Nuutila P., Knuuti J., Iozzo P., Lautamaki R., Borra R., Lehto H.R., Bucci M., Viljanen A., Parkka J., Lepomaki V., Maggio R., Parkkola R.
Effect of Caloric Restriction on Myocardial Fatty Acid Uptake, Left Ventricular Mass, and Cardiac Work in Obese Adults (2009)
- American Journal of Cardiology
Knuuti J., Iozzo P., Raitakari O., Nuutila P., Viljanen A., Karmi A., Borra R., Pärkkä J., Lepomäki V., Parkkola R., Lautamäki R., Järvisalo M., Taittonen M., Rönnemaa T.
Evaluation of αvβ3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice (2009)
- Circulation: Cardiovascular Imaging
Ylä-Herttuala S., Leppan̈en P., Walch A., Hol̈zlwimmer G., Wester H., Esposito I., Schwaiger M., Knuuti J., Laitinen I., Saraste A., Weidl E., Poethko T., Weber A., Nekolla S.