Juhani Knuuti
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
- Comparison of Ga-68-DOTA-Siglec-9 and F-18-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry (2017)
- Contrast Media and Molecular Imaging
Virtanen H, Silvola JMU, Autio A, Li XG, Liljenback H, Hellberg S, Siitonen R, Stahle M, Kakela M, Airaksinen AJ, Helariutta K, Tolvanen T, Veres TZ, Saraste A, Knuuti J, Jalkanen S, Roivainen A, Roivainen A
- Comprehensive multi-modality imaging approach in arrhythmogenic cardiomyopathy—an expert consensus document of the European Association of Cardiovascular Imaging (2017)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Kristina H. Haugaa, Cristina Basso, Luigi P. Badano, Chiara Bucciarelli-Ducci, Nuno Cardim, Oliver Gaemperli, Maurizio Galderisi, Gilbert Habib, Juhani Knuuti, Patrizio Lancellotti, William McKenna, Danilo Neglia, Bogdan A. Popescu, Thor Edvardsen
- Computed tomography versus invasive coronary angiography: design and methods of the pragmatic randomised multicentre DISCHARGE trial (2017) Napp AE, Haase R, Laule M, Schuetz GM, Rief M, Dreger H, Feuchtner G, Friedrich G, Špaček M, Suchánek V, Fuglsang Kofoed K, Engstroem T, Schroeder S, Drosch T, Gutberlet M, Woinke M, Maurovich-Horvat P1, Merkely B, Donnelly P, Ball P, Dodd JD, Quinn M, Saba L, Porcu M, Francone M, Mancone M, Erglis A, Zvaigzne L, Jankauskas A, Sakalyte G, Harań T, Ilnicka-Suckiel M, Bettencourt N, Gama-Ribeiro V, Condrea S, Benedek I, Čemerlić Adjić N, Adjić O, Rodriguez-Palomares J, Garcia Del Blanco B, Roditi G, Berry C, Davis G, Thwaite E, Knuuti J, Pietilä M, Kępka C, Kruk M, Vidakovic R, Neskovic AN, Díez I, Lecumberri I, Geleijns J, Kubiak C, Strenge-Hesse A, Do TH, Frömel F, Gutiérrez-Ibarluzea I, Benguria-Arrate G, Keiding H, Katzer C, Müller-Nordhorn J, Rieckmann N, Walther M, Schlattmann P, Dewey M; DISCHARGE Trial Group.
- Coronary computed tomography angiography derived risk score in predicting cardiac events (2017)
- Journal of Cardiovascular Computed Tomography
Uusitalo V, Kamperidis V, de Graaf MA, Maaniitty T, Stenstrom I, Broersen A, Dijkstra J, Scholte AJ, Saraste A, Bax JJ, Knuuti J
- Corrigendum to ‘2017 ESC/EACTS Guidelines for the management of valvular heart disease’ [Eur J Cardiothorac Surg 2017;52:616-664] (2017)
- European Journal of Cardio-Thoracic Surgery
Volkmar Falk, Helmut Baumgartner, Jeroen J Bax, Michele De Bonis, Christian Hamm, Per Johan Holm, Bernard Iung, Patrizio Lancellotti, Emmanuel Lansac, Daniel Rodriguez Muñoz Raphael Rosenhek, Johan Sjögren, Pilar Tornos Mas, Alec Vahanian, Thomas Walther, Olaf Wendler, Stephan Windecker, Jose Luis Zamorano, Marco Roffi, Ottavio Alfieri, Stefan Agewall, Anders Ahlsson, Emanuele Barbato, Héctor Bueno, Jean-Philippe Collet, Ioan Mircea Coman, Martin Czerny, Victoria Delgado, Donna Fitzsimons, Thierry Folliguet, Oliver Gaemperli, Gilbert Habib, Wolfgang Harringer, Michael Haude, Gerhard Hindricks, Hugo A Katus, Juhani Knuuti, Philippe Kolh, Christophe Leclercq, Theresa A McDonagh, Massimo Francesco Piepoli, Luc A Pierard, Piotr Ponikowski, Giuseppe MC Rosano, Frank Ruschitzka, Evgeny Shlyakhto, Iain A Simpson, Miguel Sousa-Uva, Janina Stepinska, Giuseppe Tarantini, Didier Tchétché, Victor Aboyans
- Decreased insulin-stimulated brown adipose tissue glucose uptake after short-term exercise training in healthy middle-aged men (2017)
- Diabetes, Obesity and Metabolism
Motiani P, Virtanen KA, Motiani KK, Eskelinen JJ, Middelbeek RJ, Goodyear LJ, Savolainen AM, Kemppainen J, Jensen J, Din MU, Saunavaara V, Parkkola R, Loyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC, Hannukainen JC
- Effects of atorvastatin and diet interventions on atherosclerotic plaque inflammation and [18F]FDG uptake in Ldlr-/-Apob100100 mice (2017) Hellberg S, Sippola S, Liljenback H, Virta J, Silvola JMU, Stahle M, Savisto N, Metso J, Jauhiainen M, Saukko P, Yla-Herttuala S, Nuutila P, Knuuti J, Roivainen A, Saraste A
- ESC 2017 guidelines on the treatment of acute myocardial infarction in patients with ST segment elevation Guía ESC 2017 sobre el tratamiento del infarto agudo de miocardio en pacientes con elevación del segmento ST (2017)
- Revista Española de Cardiología
Ibáñez B., James S., Agewall S., Antunes M.J., Bucciarelli-Ducci C., Bueno H., Caforio A.L.P., Crea F., Goudevenos J.A., Halvorsen S., Hindricks G., Kastrati A., Lenzen M.J., Prescott E., Roffi M., Valgimigli M., Varenhorst C., Vranckx P., Widimsk P., Collet J.P., Kristensen S.D., Aboyans V., Baumbach A., Bugiardini R., Mircea Coman I., Delgado V., Fitzsimons D., Gaemperli O., Gershlick A.H., Gielen S., Harjola V.P., Katus H.A., Knuuti J., Kolh P., Leclercq C., Lip G.Y.H., Morais J., Neskovic A.N., Neumann F.J., Niessner A., Piepoli M.F., Richter D.J., Shlyakhto E., Simpson I.A., Steg G., Terkelsen C.J., Thygesen K., Windecker S., Zamorano J.L., Zeymer U., Zeymer U.
- Evaluations of cardiovascular diseases with hybrid PET-CT imaging (2017) Hybrid Imaging in Cardiovascular Medicine Saraste A., Kajander S., Knuuti J.
- Exercise Training Reduces Intrathoracic Fat Regardless of Defective Glucose Tolerance (2017)
- Medicine and Science in Sports and Exercise
Sanna M. Honkala, Kumail K. Motiani, Jari-Joonas Eskelinen, Anna Savolainen, Virva Saunavaara, Kirsi A. Virtanen, Eliisa Löyttyniemi, Jukka Kapanen, Juhani Knuuti, Kari K. Kalliokoski, Jarna C. Hannukainen
- Frequency and angiographic characteristics of coronary microvascular dysfunction in stable angina: a hybrid imaging study (2017)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Stenstrom I, Maaniitty T, Uusitalo V, Pietila M, Ukkonen H, Kajander S, Maki M, Bax JJ, Knuuti J, Saraste A
- Hertta(nen sentään) (2017) Juhani Knuuti, Mika Laine
- Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography (2017)
- Journal of Translational Medicine
Grönman M, Tarkia M, Kiviniemi T, Halonen P, Kuivanen A, Savunen T, Tolvanen T, Teuho J, Käkelä M, Metsälä O, Pietilä M, Saukko P, Ylä-Herttuala S, Knuuti J, Roivainen A, Saraste A
- Insuliiniresistenssi, insuliini ja tyypin 2 diabetes (2017) Juhani Knuuti, Pauli Ohukainen, Markku Laakso
- Intensity of F-18-FDG PET Uptake in Culture-Negative and Culture-Positive Cases of Chronic Osteomyelitis (2017)
- Contrast Media and Molecular Imaging
Lankinen Petteri, Seppänen Marko, Mattila Kimmo, Kallajoki Markku, Knuuti Juhani, Aro Hannu T.
- Keinotekoinen somekohu maidosta (2017) Juhani Knuuti
- Long-Term Prognosis of Patients With Intramural Course of Coronary Arteries Assessed With CT Angiography (2017)
- JACC: Cardiovascular Imaging
Dimitriu-Leen AC, van Rosendael AR, Smit JM, van Elst T, van Geloven N, Maaniitty T, Jukema JW, Delgado V, Scholte AJHA, Saraste A, Knuuti J, Bax JJ
- Low STAT3 expression sensitizes to toxic effects of β-adrenergic receptor stimulation in peripartum
cardiomyopathy (2017) Stapel Britta, Kohlhaas Michael, Ricke-Hoch Melanie, Haghikia Arash, Erschow Sergej, Knuuti Juhani, Silvola Johanna M, Roivainen Anne, Saraste Antti, Nickel Alexander G, Saar Jasmin A, Sieve Irina, Pietzsch Stefan, Müller Mirco, Bogeski Ivan, Kappl Reinhard, Jauhiainen Matti, Thackeray James T, Scherr Michaela, Bengel Frank M, Hagl Christian, Tudorache Igor, Bauersachs Johann, Maack Christoph, Hilfiker-Kleiner Denise
- Nosebo (2017) Juhani Knuuti
- PET imaging in heart failure: the role of new tracers (2017) Saraste A, Knuuti J
