MD, professor, Turku PET Centre Juhani Knuuti - UTU Research Portal

Juhani Knuuti
MD, professor, Turku PET Centre

- Director,
- Professor,
Turku PET Centre (Independent units)
- ,
InFLAMES Flagship (Faculty of Medicine)

jknuuti@utu.fi

+358 29 450 2345

+358 50 059 2998

Kiinamyllynkatu 4-8

Turku

ORCID identifier: https://orcid.org/0000-0003-3156-9593

CV J Knuuti 5th February 2021_signed.pdf

Research community or research topic

Cardiovascular diseases, imaging

Biography

Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.

Publications

37 of 55

Tissue specificity in fasting glucose utilization in slightly obese diabetic patients submitted to bariatric surgery (2013)
- Obesity
Morbelli S, Marini C, Adami GF, Kudomi N, Camerini G, Iozzo P, Massollo M, Capitanio S, Bodrato S, Verardi MT, Papadia F, Cordera R, Knuuti J, Scopinaro N, Sambuceti G
(A1 Refereed original research article in a scientific journal)
Updated detailed ESC guidelines for the management of atrial fibrillation, 2012 Actualización detallada de las guías de la ESC para el manejo de la fibrilación auricular de 2012: Actualización de las guías de la Sociedad Europea de Cardiología (ESC) para el manejo de la fibrilación auricular de 2010 Elaborada en colaboración con la Asociación Europea del Ritmo Cardiaco (2013)
- Revista Española de Cardiología
Camm A.J., Lip G.Y.H., Caterina R.D., Savelieva I., Atar D., Hohnloser S.H., Hindricks G., Kirchhof P., Bax J.J., Baumgartner H., Ceconi C., Dean V., Deaton C., Fagard R., Funck-Brentano C., Hasdai D., Knuuti J., Kolh P., McDonagh T., Moulin C., Popescu B.A., Reiner Z., Sechtem U., Anton Sirnes P., Tendera M., Torbicki A., Vahanian A., Windecker S., Vardas P., Al-Attar N., Alfieri O., Angelini A., Blömstrom-Lundqvist C., Colonna P., De Sutter J., Ernst S., Goette A., Gorenek B., Hatala R., Heidbüchel H., Heldal M., Dalby Kristensen S., Le Heuzey J.Y., Mavrakis H., Mont L., Perrone Filardi P., Ponikowski P., Prendergast B., Rutten F.H., Schotten U., Van Gelder I.C., Verheugt F.W.A.
(A1 Refereed original research article in a scientific journal)
Validation of [F-18]fluorodeoxyglucose and positron emission tomography (PET) for the measurement of intestinal metabolism in pigs, and evidence of intestinal insulin resistance in patients with morbid obesity (2013)
- Diabetologia
Honka H, Makinen J, Hannukainen JC, Tarkia M, Oikonen V, Teras M, Fagerholm V, Ishizu T, Saraste A, Stark C, Vahasilta T, Salminen P, Kirjavainen A, Soinio M, Gastaldelli A, Knuuti J, Iozzo P, Nuutila P
(A1 Refereed original research article in a scientific journal)
2012 focused update of the ESC Guidelines for the management of atrial fibrillation: An update of the 2010 ESC Guidelines of the management of atrial fibrillation -- Developed with the special contribution of the European Heart Rhythm Association (2012)
- EP-Europace
Camm AJ, Lip GY, De Caterina R, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P, ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S, Document Reviewers, Vardas P Al-Attar N, Alfieri O, Angelini A, Blömstrom-Lundqvist C, Colonna P, De Sutter J, Ernst S, Goette A, Gorenek B, Hatala R, Heidbüchel H, Heldal M, Kristensen SD, Kolh P, Le Heuzey JY, Mavrakis H, Mont L, Filardi PP, Ponikowski P, Prendergast B, Rutten FH, Schotten U, Van Gelder IC, Verheugt FW
(A1 Refereed original research article in a scientific journal)
2012 focused update of the ESC Guidelines for the management of atrial fibrillation: An update of the 2010 ESC Guidelines of the management of atrial fibrillation -- Developed with the special contribution of the European Heart Rhythm Association (2012)
- European Heart Journal
Camm AJ, Lip GY, De Caterina R, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P, ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S, Document Reviewers, Vardas P Al-Attar N, Alfieri O, Angelini A, Blömstrom-Lundqvist C, Colonna P, De Sutter J, Ernst S, Goette A, Gorenek B, Hatala R, Heidbüchel H, Heldal M, Kristensen SD, Kolh P, Le Heuzey JY, Mavrakis H, Mont L, Filardi PP, Ponikowski P, Prendergast B, Rutten FH, Schotten U, Van Gelder IC, Verheugt FW
(A1 Refereed original research article in a scientific journal)
Adolescence Risk Factors Are Predictive of Coronary Artery Calcification at Middle Age: The Cardiovascular Risk in Young Finns Study (2012)
- Journal of the American College of Cardiology
Hartiala O, Magnussen CG, Kajander S, Knuuti J, Ukkonen H, Saraste A, Rinta-Kiikka I, Kainulainen S, Kahonen M, Hutri-Kahonen N, Laitinen T, Lehtimaki T, Viikari JSA, Hartiala J, Juonala M, Raitakari OT
(A1 Refereed original research article in a scientific journal)
Advances in clinical application of quantitative myocardial perfusion imaging (2012)
- Journal of Nuclear Cardiology
Knuuti J, Saraste A
(A1 Refereed original research article in a scientific journal)
Amyloid Targeting Tracer [F-18]flutemetamol is Accumulated in Atherosclerotic Plaques (2012)
- European Journal of Nuclear Medicine and Molecular Imaging
Hellberg SE, Saraste A, Silvola JMU, Eskola O, Liljenback H, Laine J, Lehikoinen P, Saukko P, Horkko S, Knuuti J, Roivainen A
(Other publication)
Bone Blood Flow at Rest and During Exercise in Humans Measured with Positron Emission Tomography (2012)
- Medicine and Science in Sports and Exercise
Medicine and Science in Sports and Exercise Kalliokoski K, Kaskinoro K, Kemppainen J, Knuuti J, Heinonen I
(Other publication)
Both BMI and Waist Circumference Are Associated with Coronary Vasoreactivity in Overweight and Obese Men (2012)
- Obesity Facts
Sundell J, Raitakari OT, Viikari J, Kantola I, Nuutila P, Knuuti J
(A1 Refereed original research article in a scientific journal)
Cardiac function, perfusion, metabolism, and innervation following autologous stem cell therapy for acute ST-elevation myocardial infarction – A FINCELL-INSIGHT sub-study with PET and MRI (2012)
- Frontiers in Physiology
Mäki MT, Juha W Koskenvuo, Heikki Ukkonen, Antti Saraste, Helena Tuunanen, Mikko Pietilä, Sergey V Nesterov, Ville Aalto, K E Juhani Airaksinen, Jussi P Pärkkä, Riikka Lautamäki, Kari Kervinen, Johanna A Miettinen, Timo H Mäkikallio, Matti Niemelä, Marjaana Säily, Pirjo Koistinen, Eeva-Riitta Savolainen, Kari Ylitalo, Heikki V Huikuri, Juhani Knuuti
(A1 Refereed original research article in a scientific journal)
Cardiac hybrid imaging (2012)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Gaemperli O, Saraste A, Knuuti J
(A1 Refereed original research article in a scientific journal)
Cardiac imaging: does radiation matter? (2012)
- European Heart Journal
Einstein AJ, Knuuti J
(A1 Refereed original research article in a scientific journal)
Cardiac PET, CT, and MR: What Are the Advantages of Hybrid Imaging? (2012)
- Current Cardiology Reports
Saraste A, Knuuti J
(A1 Refereed original research article in a scientific journal)
CMR versus SPECT for diagnosis of coronary heart disease (2012)
- Lancet
Flotats A, Bengel FM, Knuuti J, Le Guludec D, Marcassa C
(A1 Refereed original research article in a scientific journal)
Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer F-18-galacto-RGD in mouse atherosclerotic plaques (2012)
- Journal of Nuclear Cardiology
Saraste A, Laitinen I, Weidl E, Wildgruber M, Weber AW, Nekolla SG, Holzlwimmer G, Esposito I, Walch A, Leppanen P, Lisinen I, Luppa PB, Yla-Herttuala S, Wester HJ, Knuuti J, Schwaiger M
(A1 Refereed original research article in a scientific journal)
Effects of Acute and One-Week Fatty Acid Lowering on Cardiac Function and Insulin Sensitivity in Relation with Myocardial and Muscle Fat and Adiponectin Levels (2012)
- Journal of Clinical Endocrinology and Metabolism
Lehto HR, Parkka J, Borra R, Tuunanen H, Lepomaki V, Parkkola R, Knuuti J, Nuutila P, Iozzo P
(A1 Refereed original research article in a scientific journal)
Effects of adenosine, exercise, and moderate acute hypoxia on energy substrate utilization of human skeletal muscle (2012)
- AJP - Regulatory, Integrative and Comparative Physiology
Heinonen I, Kemppainen J, Kaskinoro K, Peltonen JE, Sipila HT, Nuutila P, Knuuti J, Boushel R, Kalliokoski KK
(A1 Refereed original research article in a scientific journal)
Effects of high-intensity interval training on glucose and fat metabolism in healthy, sedentary middle aged men (2012)
- Diabetologia
Savolainen AM, Kalliokoski KK, Eskelinen JJ, Lepomaki V, Heinonen I, Virtanen K, Parkkola R, Kapanen J, Knuuti J, Nuutila P, Hannukainen JC
(Other publication)
Erratum: 'European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)' the Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts) (2012)
- European Heart Journal
Perk J., De Backer G., Gohlke H., Graham I., Reiner Z., Verschuren W.M.M., Albus C., Benlian P., Boysen G., Cifkova R., Deaton C., Ebrahim S., Fisher M., Germano G., Hobbs R., Hoes A., Karadeniz S., Mezzani A., Prescott E., Ryden L., Scherer M., Syvänne M., Scholte Op Reimer W.J., Vrints C., Wood D., Zamorano J.L., Zannad F., Cooney M.T., Bax J., Baumgartner H., Ceconi C., Dean V., Deaton C., Fagard R., Funck-Brentano C., Hasdai D., Hoes A., Kirchhof P., Knuuti J., Kolh P., McDonagh T., Moulin C., Popescu B.A., Reiner Z., Sechtem U., Sirnes P.A., Tendera M., Torbicki A., Vahanian A., Windecker S., Funck-Brentano C., Sirnes P.A., Aboyans V., Ezquerra E.A., Baigent C., Brotons C., Burell G., Ceriello A., De Sutter J., Deckers J., Del Prato S., Diener H.C., Fitzsimons D., Fras Z., Hambrecht R., Jankowski P., Keil U., Kirby M., Larsen M.L., Mancia G., Manolis A.J., McMurray J., Pajak A., Parkhomenko A., Rallidis L., Rigo F., Rocha E., Ruilope L.M., Van Der Velde E., Vanuzzo D., Viigimaa M., Volpe M., Wiklund O., Wolpert C., Volpe M., Viigimaa M., Wolpert C., Wiklund O., Vanuzzo D.
(Other publication)