Juhani Knuuti
MD, professor, Turku PET Centre
Research community or research topic
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
- Revascularisation versus medical treatment in patients with stable coronary artery disease: network meta-analysis. (2014) Windecker S, Stortecky S, Stefanini GG, da Costa BR, Rutjes AW, Di Nisio M, Silletta MG, Maione A, Alfonso F, Clemmensen PM, Collet JP, Cremer J, Falk V, Filippatos G, Hamm C, Head S, Kappetein AP, Kastrati A, Knuuti J, Landmesser U, Laufer G, Neumann FJ, Richter D, Schauerte P, Sousa Uva M, Taggart DP, Torracca L, Valgimigli M, Wijns W, Witkowski A, Kolh P, Jüni P
(A1 Refereed original research article in a scientific journal)
- Risks and benefits of cardiac imaging: an analysis of risks related to imaging for coronary artery disease (2014) Knuuti J, Bengel F, Bax JJ, Kaufmann PA, Le Guludec D, Perrone Filardi P, Marcassa C, Ajmone Marsan N, Achenbach S, Kitsiou A, Flotats A, Eeckhout E, Minn H, Hesse B
(A1 Refereed original research article in a scientific journal)
- Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology. 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. (2014) Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galiè N, Gibbs JS, Huisman MV, Humbert M, Kucher N, Lang I, Lankeit M, Lekakis J, Maack C, Mayer E, Meneveau N, Perrier A, Pruszczyk P, Rasmussen LH, Schindler TH, Svitil, P, Vonk Noordegraaf A, Zamorano JL, Zompatori M; ESC Committee for Practice Guidelines (CPG), Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R (Italy), Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S
(A1 Refereed original research article in a scientific journal)
- The appropriate and justified use of medical radiation in cardiovascular imaging: a position document of the ESC Associations of Cardiovascular Imaging, Percutaneous Cardiovascular Interventions and Electrophysiology (2014) Picano Eugenio, Vano Eliseo, Rehani Madan M, Cuocolo Alberto, Mont Lluis, Bodi Vicente, Bar Olivier, Maccia Carlo, Pierard Luc, Sicari Rosa, Plein Sven, Mahrholdt Heiko, Lancellotti Patrizio, Knuuti Juhani, Heidbuchel Hein, Di Mario Carlo, Badano Luigi P
(A1 Refereed original research article in a scientific journal)
- The effects of increasing vagal stimulation on central hemodynamics, cardiac function, and coronary blood flow (2014) Heinonen I, Hekkert MVTL, Knuuti J, Duncker DJ
(Other publication)
- The functional effects of intramyocardial course of coronary arteries and its relation to coronary atherosclerosis (2014) V. Uusitalo, A. Saraste, M. Pietila, S. Kajander, M. Maki, J.J. Bax, J. Knuuti; on behalf of Finnish Centre of Excellence in Molecular Imaging in Cardiovascular and Metabolic Research
(Other publication)
- The year 2013 in the European Heart Journal - Cardiovascular Imaging: Part I (2014)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Edvardsen T, Plein S, Saraste A, Pierard LA, Knuuti J, Maurer G, Lancellotti P.
(A1 Refereed original research article in a scientific journal)
- The year 2013 in the European Heart Journal - Cardiovascular Imaging: Part II (2014)
- EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Plein S, Edvardsen T, Pierard LA, Saraste A, Knuuti J, Maurer G, Lancellotti P.
(A1 Refereed original research article in a scientific journal)
- Using 5-deoxy-5-[F-18] fluororibose to glycosylate peptides for positron emission tomography (2014) Li XG, Helariutta K, Roivainen A, Jalkanen S, Knuuti J, Airaksinen AJ
(A1 Refereed original research article in a scientific journal)
- VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. (2014) Kivelä R1, Bry M, Robciuc MR, Räsänen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, Mäyränpää MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K.
(A1 Refereed original research article in a scientific journal)
- Vertebral bone marrow glucose uptake is inversely associated with bone marrow fat in diabetic and healthy pigs: [18F]FDG-PET and MRI study (2014) Huovinen V., Saunavaara V., Kiviranta R., Tarkia M., Honka H., Stark C., Laine J., Linderborg K., Tuomikoski P., Badeau R., Knuuti J., Nuutila P., Parkkola R.
(A1 Refereed original research article in a scientific journal)
- V˙O2peak, Myocardial Hypertrophy, and Myocardial Blood Flow in Endurance-Trained Men (2014)
- Medicine and Science in Sports and Exercise
Laaksonen MS, Heinonen I, Luotolahti M, Knuuti J, Kalliokoski KK
(A1 Refereed original research article in a scientific journal)
- Wytyczne ESC/EACTS dotyczace rewaskularyzacji miȩśnia sercowego w 2014 roku [2014 ESC/EACTS Guidelines on myocardial revascularization] (2014) Windecker S, Kolh P, Alfonso F, Collet JP, Cremer J, Falk V, Filippatos G, Hamm C, Head SJ, Jüni P, Kappetein AP, Kastrati A, Knuuti J, Landmesser U, Laufer G, Neumann FJ, Richter DJ, Schauerte P, Uva MS, Stefanini GG, Taggart DP, Torracca L, Valgimigli M, Wijns W, Witkowski A
(Other publication)
- 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy (2013) Brignole M, Auricchio A, Baron-Esquivias G, Bordachar P, Boriani G, Breithardt OA, Cleland J, Deharo JC, Delgado V, Elliott PM, Gorenek B, Israel CW, Leclercq C, Linde C, Mont L, Padeletti L, Sutton R, Vardas PE, Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S, Kirchhof P, Blomstrom-Lundqvist C, Badano LP, Aliyev F, Bnsch D, Baumgartner H, Bsata W, Buser P, Charron P, Daubert JC, Dobreanu D, Faerestrand S, Hasdai D, Hoes AW, Le Heuzey JY, Mavrakis H, McDonagh T, Merino JL, Nawar MM, Nielsen JC, Pieske B, Poposka L, Ruschitzka F, Tendera M, Van Gelder IC, Wilson CM
(A1 Refereed original research article in a scientific journal)
- 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy The Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA) (2013) Michele Brignole, Angelo Auricchio, Gonzalo Baron-Esquivias, Pierre Bordachar, Giuseppe Boriani, Ole-A Breithardt, John Cleland, Jean-Claude Deharo, Victoria Delgado, Perry M Elliott, Bulent Gorenek, Carsten W Israel, Christophe Leclercq, Cecilia Linde, Lluís Mont, Luigi Padeletti, Richard Sutton, Panos E Vardas, Jose Luis Zamorano, Stephan Achenbach, Helmut Baumgartner, Jeroen J Bax, Héctor Bueno, Veronica Dean, Christi Deaton, Cetin Erol, Robert Fagard, Roberto Ferrari, David Hasdai, Arno W Hoes, Paulus Kirchhof, Juhani Knuuti, Philippe Kolh, Patrizio Lancellotti, Ales Linhart, Petros Nihoyannopoulos, Massimo F Piepoli, Piotr Ponikowski, Per Anton Sirnes, Juan Luis Tamargo, Michal Tendera, Adam Torbicki, William Wijns, Stephan Windecker, Paulus Kirchhof, Carina Blomstrom-Lundqvist, Luigi P Badano, Farid Aliyev, Dietmar Bänsch, Helmut Baumgartner, Walid Bsata, Peter Buser, Philippe Charron, Jean-Claude Daubert, Dan Dobreanu, Svein Faerestrand, David Hasdai, Arno W Hoes, Jean-Yves Le Heuzey, Hercules Mavrakis, Theresa McDonagh, Jose Luis Merino, Mostapha M Nawar, Jens Cosedis Nielsen, Burkert Pieske, Lidija Poposka, Frank Ruschitzka, Michal Tendera, Isabelle C Van Gelder, Carol M Wilson
(A1 Refereed original research article in a scientific journal)
- 2013 ESC guidelines on the management of stable coronary artery disease (2013) Sechtem U, Achenbach S, Andreotti F, Budaj A, Bugiardini R, Crea F, Cuisset T, Di Mario C, Ferreira JR, Gersh BJ, Gitt AK, Hulot JS, Marx N, Opie LH, Pfisterer M, Prescott E, Ruschitzka F, Sabate M, Senior R, Taggart DP, van der Wall EE, Vrints CJM, Knuuti J, Valgimigli M, Bueno H, Claeys MJ, Donner-Banzhoff N, Erol C, Frank H, Funck-Brentano C, Gaemperli O, Gonzalez-Juanatey JR, Hamilos M, Hasdai D, Husted S, James SK, Kervinen K, Kolh P, Kristensen SD, Lancellotti P, Maggioni AP, Piepoli MF, Pries AR, Romeo F, Ryden L, Simoons ML, Sirnes PA, Steg PG, Timmis A, Wijns W, Windecker S, Yildirir A, Zamorano JL
(A1 Refereed original research article in a scientific journal)
- 2013 ESH/ESC Guidelines for the management of arterial hypertension (2013) Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Bohm M, Christiaens T, Cifkova R, De Backer G, Dominiczak A, Galderisi M, Grobbee DE, Jaarsma T, Kirchhof P, Kjeldsen SE, Laurent S, Manolis AJ, Nilsson PM, Ruilope LM, Schmieder RE, Sirnes PA, Sleight P, Viigimaa M, Waeber B, Zannad F, Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S
(A1 Refereed original research article in a scientific journal)
- 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) (2013) Mancia G, Fagard R, Narkiewicz K, Redón J, Zanchetti A, Böhm M, Christiaens T, Cifkova R, De Backer G, Dominiczak A, Galderisi M, Grobbee DE, Jaarsma T, Kirchhof P, Kjeldsen SE, Laurent S, Manolis AJ, Nilsson PM, Ruilope LM, Schmieder RE , Sirnes PA, Sleight P, Viigimaa M, Waeber B, Zannad F
(A1 Refereed original research article in a scientific journal)
- Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial (2013) O'Meara E, Mielniczuk LM, Wells GA, deKemp RA, Klein R, Coyle D, Mc Ardle B, Paterson I, White JA, Arnold M, Friedrich MG, Larose E, Dick A, Chow B, Dennie C, Haddad H, Ruddy T, Ukkonen H, Wisenberg G, Cantin B, Pibarot P, Freeman M, Turcotte E, Connelly K, Clarke J, Williams K, Racine N, Garrard L, Tardif JC, DaSilva J, Knuuti J, Beanlands R
(A1 Refereed original research article in a scientific journal)
- Anatomic Versus Physiologic Assessment of Coronary Artery Disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making (2013)
- Journal of the American College of Cardiology
Gould KL, Johnson NP, Bateman TM, Beanlands RS, Bengel FM, Bober R, Camici PG, Cerqueira MD, Chow BJW, Di Carli MF, Dorbala S, Gewirtz H, Gropler RJ, Kaufmann PA, Knaapen P, Knuuti J, Merhige ME, Rentrop KP, Ruddy TD, Schelbert HR, Schindler TH, Schwaiger M, Sdringola S, Vitarello J, Williams KA, Gordon D, Dilsizian V, Narula J
(A1 Refereed original research article in a scientific journal)
