Harri Niinikoski
Professor, Nutrition in Medicine (Institute of Biomedicine)
Areas of expertise
Childhood endocrinology and nutrition; inherited metabolic diseases; neonatal screening; prevention of cardiovascular risk factors.
Biography
Professor Harri Niinikoski graduated from the Medical School at the University of Turku
in 1991, where he also specialized in Pediatrics in 2000 and received
subspecialty in Pediatric Endocrinology in 2006. He defended his thesis on prevention
of cardiovascular risk factors in childhood in 1997 (The STRIP study). He did
his post-doc training at the Childhood Nutrition Research Center at the Baylor
School of Medicine, Houston, Texas, in 2001-2003. Subsequently, he worked as a
Senior Clinical Researcher and Clinical Lecturer at the Department of Pediatrics,
University of Turku, and in 2011-2015 as the Head of the Division of Pediatric
Care in Turku University Hospital. From 2015, he has been Professor of Nutrition
in Medicine
Research
Professor Harri Niinikoski’s research interest focus on primary prevention of
cardiovascular disease, and childhood nutrition, endocrinology and metabolism.
Moreover, he has been closely involved in launching the neonatal metabolic
screening program which started in Finland in 2015.
Main research projects are 1) The STRIP study (The Special Turku coronary risk
factor Intervention Project) which started in 1990 and involved 1062 infants
which were randomized into nutrition an intervention or a control group. He is deputy P.I. in STRIP; 2) DIARA2 study which involves 317 children (217 in
Turku, 100 in Oulu) whose mothers were treated with either metformin or insulin
due to gestational diabetes. The children are now thoroughly investigated at 9
years of age; 3) LPI study. Lysinuric protein intolerance (LPI) is a rare
metabolic disease which belongs to the Finnish disease heritage. There are
approx. 50 Finnish patients who are annually studied at the Turku University
Hospital pediatric metabolic outpatient clinic; 4) Congenital
hypothyroidism study. CH has been screened in Finland since 1980, affects
1:2000 newborns and is treated with thyroxine. The outcome of the treatment of
CH is investigated in national CH study which is launched in 2018.
Teaching
In 2006-2010, Harri Niinikoski worked as a full-time teacher of pediatrics at the
Department of Pediatrics, University of Turku.
Publications
- Effects of 20-year infancy-onset dietary counselling on cardiometabolic risk factors in the Special Turku Coronary Risk Factor Intervention Project (STRIP): 6-year post-intervention follow-up (2020)
- The Lancet Child & Adolescent Health
Katja Pahkala, Tomi T. Laitinen, Harri Niinikoski, Noora Kartiosuo, Suvi P. Rovio, Hanna Lagström, Britt-Marie Loo, Pia Salo, Eero Jokinen, Costan G. Magnussen, Markus Juonala, Olli Simell, Antti Jula, Tapani Rönnemaa, Jorma Viikari, Olli T. Raitakari
(A1 Refereed original research article in a scientific journal)
- Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood (2020)
- European Journal of Epidemiology
Zheng Y., Huang T., Wang T., Mei Z., Sun Z., Zhang T., Ellervik C., Chai J.-F., Sim X., van Dam R.M., Tai E.-S., Koh W.-P., Dorajoo R., Saw S.-M., Sabanayagam C., Wong T.Y., Gupta P., Rossing P., Ahluwalia T.S., Vinding R.K., Bisgaard H., Bønnelykke K., Wang Y., Graff M., Voortman T., van Rooij F.J.A., Hofman A., van Heemst D., Noordam R., Estampador A.C., Varga T.V., Enzenbach C., Scholz M., Thiery J., Burkhardt R., Orho-Melander M., Schulz C.-A., Ericson U., Sonestedt E., Kubo M., Akiyama M., Zhou A., Kilpeläinen T.O., Hansen T., Kleber M.E., Delgado G., McCarthy M., Lemaitre R.N., Felix J.F., Jaddoe V.W.V., Wu Y., Mohlke K.L., Lehtimäki T., Wang C.A., Pennell C.E., Schunkert H., Kessler T., Zeng L., Willenborg C., Peters A., Lieb W., Grote V., Rzehak P., Koletzko B., Erdmann J., Munz M., Wu T., He M., Yu C., Lecoeur C., Froguel P., Corella D., Moreno L.A., Lai C.-Q., Pitkänen N., Boreham C.A., Ridker P.M., Rosendaal F.R., de Mutsert R., Power C., Paternoster L., Sørensen T.I.A., Tjønneland A., Overvad K., Djousse L., Rivadeneira F., Lee N.R., Raitakari O.T., Kähönen M., Viikari J., Langhendries J.-P., Escribano J., Verduci E., Dedoussis G., König I., Balkau B., Coltell O., Dallongeville J., Meirhaeghe A., Amouyel P., Gottrand F., Pahkala K., Niinikoski H., Hyppönen E., März W., Mackey D.A., Gruszfeld D., Tucker K.L., Fumeron F., Estruch R., Ordovas J.M., Arnett D.K., Mook-Kanamori D.O., Mozaffarian D., Psaty B.M., North K.E., Chasman D.I., Qi L.
(A1 Refereed original research article in a scientific journal)
- Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits (2020) Vogelezang S, Bradfield JP, Ahluwalia TS, Curtin JA, Lakka TA, Grarup N, Scholz M, van der Most PJ, Monnereau C, Stergiakouli E, Heiskala A, Horikoshi M, Fedko IO, Vilor-Tejedor N, Cousminer DL, Standl M, Wang CRA, Viikari J, Geller F, Iniguez C, Pitkanen N, Chesi A, Bacelis J, Yengo L, Torrent M, Ntalla I, Helgeland O, Selzam S, Vonk JM, Zafarmand MH, Heude B, Farooqi IS, Alyass A, Beaumont RN, Have CT, Rzehak P, Bilbao JR, Schnurr TM, Barroso I, Bonnelykke K, Beilin LJ, Carstensen L, Charles MA, Chawes B, Clement K, Closa-Monasterolo R, Custovic A, Eriksson JG, Escribano J, Groen-Blokhuis M, Grote V, Gruszfeld D, Hakonarson H, Hansen T, Hattersley AT, Hollensted M, Hottenga JJ, Hypponen E, Johansson S, Joro R, Kahonen M, Karhunen V, Kiess W, Knight BA, Koletzko B, Kuhnapfel A, Landgraf K, Langhendries JP, Lehtimaki T, Leinonen JT, Li AHL, Lindi V, Lowry E, Bustamante M, Medina-Gomez C, Melbye M, Michaelsen KF, Morgen CS, Mori TA, Nielsen TRH, Niinikoski H, Oldehinkel AJ, Pahkala K, Panoutsopoulou K, Pedersen O, Pennell CE, Power C, Reijneveld SA, Rivadeneira F, Simpson A, Sly PD, Stokholm J, Teo KK, Thiering E, Timpson NJ, Uitterlinden AG, van Beijsterveldt CEM, van Schaik BDC, Vaudel M, Verduci E, Vinding RK, Vogel M, Zeggini E, Sebert S, Lind MV, Brown CD, Santa-Marina L, Reischl E, Frithioff-Bojsoe C, Meyre D, Wheeler E, Ong K, Nohr EA, Vrijkotte TGM, Koppelman GH, Plomin R, Njolstad PR, Dedoussis GD, Froguel P, Sorensen TIA, Jacobsson B, Freathy RM, Zemel BS, Raitakari O, Vrijheid M, Feenstra B, Lyytikainen LP, Snieder H, Kirsten H, Holt PG, Heinrich J, Widen E, Sunyer J, Boomsma DI, Jarvelin MR, Korner A, Smith GD, Holm JC, Atalay M, Murray C, Bisgaard H, McCarthy MI, Jaddoe VWV, Grant SFA, Felix JF
(A1 Refereed original research article in a scientific journal)
- Temperament profiles are associated with dietary behavior from childhood to adulthood (2020) Lipsanen J., Elovainio M., Hakulinen C., Tremblay M.S., Rovio S., Lagström H., Jaakkola J.M., Jula A., Rönnemaa T., Viikari J., Niinikoski H., Simell O., Raitakari O.T., Pahkala K., Pulkki-Råback L.
(A1 Refereed original research article in a scientific journal)
- Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study (2019) Huang T, Wang TA, Zheng Y, Ellervik C, Li X, Gao M, Fang Z, Chai JF, Ahluwalia TVS, Wang YJ, Voortman T, Noordam R, Frazier-Wood A, Scholz M, Sonestedt E, Akiyama M, Dorajoo R, Zhou A, Kilpelainen TO, Kleber ME, Crozier SR, Godfrey KM, Lemaitre R, Felix JF, Shi Y, Gupta P, Khor CC, Lehtimaki T, Wang CA, Tiesler CMT, Thiering E, Standl M, Rzehak P, Marouli E, He M, Lecoeur C, Corella D, Lai CQ, Moreno LA, Pitkanen N, Boreham CA, Zhang T, Saw SM, Ridker PM, Graff M, Van Rooij FJA, Uitterlinden AG, Hofman A, van Heemst D, Rosendaal FR, de Mutsert R, Burkhardt R, Schulz CA, Ericson U, Kamatani Y, Yuan JM, Power C, Hansen T, Sorensen TIA, Tjonneland A, Overvad K, Delgado G, Cooper C, Djousse L, Rivadeneira F, Jameson K, Zhao W, Liu JJ, Lee NR, Raitakari O, Kahonen M, Viikari J, Grote V, Langhendries JP, Koletzko B, Escribano J, Verduci E, Dedoussis G, Yu CZ, Tham YC, Lim B, Lim SH, Froguel P, Balkau B, Fink NR, Vinding RK, Sevelsted A, Bisgaard H, Coltell O, Dallongeville J, Gottrand F, Pahkala K, Niinikoski H, Hypponen E, Pedersen O, Marz W, Inskip H, Jaddoe VV, Dennison E, YinWong T, Sabanayagam C, Tai ES, Mohlke KL, Mackey DA, Gruszfeld D, Deloukas P, Tucker KL, Fumeron F, Bonnelykke K, Rossing P, Estruch R, Ordovas JM, Arnett DK, Meirhaeghe A, Amouyel P, Cheng CY, Sim XL, Teo YY, van Dam R, Koh WP, Orho-Melander M, Loeffler M, Kubo M, Thiery J, Mook-Kanamori DO, Mozaffarian D, Psaty BM, Franco OH, Wu TC, North KE, Smith GD, Chavarro JE, Chasman DI, Qi L
(A1 Refereed original research article in a scientific journal)
- Longitudinal effect of 20-year infancy-onset dietary intervention on food consumption and nutrient intake: the randomized controlled STRIP study (2019)
- European Journal of Clinical Nutrition
Laurie A. Matthews, Suvi P. Rovio, Johanna M Jaakkola, Harri Niinikoski, Hanna Lagström, Antti Jula, Jorma S. A. Viikari, Tapani Rönnemaa, Olli Simell, Olli T. Raitakari, Katja Pahkala
(A1 Refereed original research article in a scientific journal)
- Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents (2019) Sergey Sadov, Helena E. Virtanen, Katharina M. Main, Anna‐Maria Andersson, Anders Juul, Antti Jula, Olli T. Raitakari, Katja Pahkala, Harri Niinikoski, Jorma Toppari
(A1 Refereed original research article in a scientific journal)
- Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors (2019) Warrington N.M., Beaumont R.N., Horikoshi M., Day F.R., Helgeland Ø., Laurin C., Bacelis J., Peng S., Hao K., Feenstra B., Wood A.R., Mahajan A., Tyrrell J., Robertson N.R., Rayner N.W., Qiao Z., Moen G.-H., Vaudel M., Marsit C.J., Chen J., Nodzenski M., Schnurr T.M., Zafarmand M.H., Bradfield J.P., Grarup N., Kooijman M.N., Li-Gao R., Geller F., Ahluwalia T.S., Paternoster L., Rueedi R., Huikari V., Hottenga J.-J., Lyytikäinen L.-P., Cavadino A., Metrustry S., Cousminer D.L., Wu Y., Thiering E., Wang C.A., Have C.T., Vilor-Tejedor N., Joshi P.K., Painter J.N., Ntalla I., Myhre R., Pitkänen N., van Leeuwen E.M., Joro R., Lagou V., Richmond R.C., Espinosa A., Barton S.J., Inskip H.M., Holloway J.W., Santa-Marina L., Estivill X., Ang W., Marsh J.A., Reichetzeder C., Marullo L., Hocher B., Lunetta K.L., Murabito J.M., Relton C.L., Kogevinas M., Chatzi L., Allard C., Bouchard L., Hivert M.-F., Zhang G., Muglia L.J., Heikkinen J., Morgen C.S., van Kampen A.H.C., van Schaik B.D.C., Mentch F.D., Langenberg C., Luan J., Scott R.A., Zhao J.H., Hemani G., Ring S.M., Bennett A.J., Gaulton K.J., Fernandez-Tajes J., van Zuydam N.R., Medina-Gomez C., de Haan H.G., Rosendaal F.R., Kutalik Z., Marques-Vidal P., Das S., Willemsen G., Mbarek H., Müller-Nurasyid M., Standl M., Appel E.V.R., Fonvig C.E., Trier C., van Beijsterveldt C.E.M., Murcia M., Bustamante M., Bonas-Guarch S., Hougaard D.M., Mercader J.M., Linneberg A., Schraut K.E., Lind P.A., Medland S.E., Shields B.M., Knight B.A., Chai J.-F., Panoutsopoulou K., Bartels M., Sánchez F., Stokholm J., Torrents D., Vinding R.K., Willems S.M., Atalay M., Chawes B.L., Kovacs P., Prokopenko I., Tuke M.A., Yaghootkar H., Ruth K.S., Jones S.E., Loh P.-R., Murray A., Weedon M.N., Tönjes A., Stumvoll M., Michaelsen K.F., Eloranta A.-M., Lakka T.A., van Duijn C.M., Kiess W., Körner A., Niinikoski H., Pahkala K., Raitakari O.T., Jacobsson B., Zeggini E., Dedoussis G.V., Teo Y.-Y., Saw S.-M., Montgomery G.W., Campbell H., Wilson J.F., Vrijkotte T.G.M., Vrijheid M., de Geus E.J.C.N., Hayes M.G., Kadarmideen H.N., Holm J.-C., Beilin L.J., Pennell C.E., Heinrich J., Adair L.S., Borja J.B., Mohlke K.L., Eriksson J.G., Widén E.E., Hattersley A.T., Spector T.D., Kähönen M., Viikari J.S., Lehtimäki T., Boomsma D.I., Sebert S., Vollenweider P., Sørensen T.I.A., Bisgaard H., Bønnelykke K., Murray J.C., Melbye M., Nohr E.A., Mook-Kanamori D.O., Rivadeneira F., Hofman A., Felix J.F., Jaddoe V.W.V., Hansen T., Pisinger C., Vaag A.A., Pedersen O., Uitterlinden A.G., Järvelin M.-R., Power C., Hyppönen E., Scholtens D.M., Lowe W.L., Jr, Davey Smith G., Timpson N.J., Morris A.P., Wareham N.J., Hakonarson H., Grant S.F.A., Frayling T.M., Lawlor D.A., Njølstad P.R., Johansson S., Ong K.K., McCarthy M.I., Perry J.R.B., Evans D.M., Freathy R.M.; EGG Consortium
(A1 Refereed original research article in a scientific journal)
- Abnormal coagulation and enhanced fibrinolysis due to lysinuric protein intolerance associates with bleeds and renal impairment (2018) Zuurveld M., Kopatz W., Brinkman H., Meijers J., Lassila R., Pitkänen H., Kärki M., Niinikoski H., Tanner L., Näntö-Salonen K., Pikta M.
(A1 Refereed original research article in a scientific journal)
- Effect of Dietary Counseling on a Comprehensive Metabolic Profile from Childhood to Adulthood (2018) Miia Lehtovirta, Katja Pahkala, Harri Niinikoski, Antti J. Kangas, Pasi Soininen, Hanna Lagström, Jorma S.A. Viikari, Tapani Rönnemaa, Antti Jula, Mika Ala-Korpela, Peter Würtz, Olli T. Raitakari
(A1 Refereed original research article in a scientific journal)
- Lysinuric Protein Intolerance (2018) Virginia Nunes, Harri Niinikoski
(A2 Refereed review article in a scientific journal )
- Maternal and fetal genetic contribution to gestational weight gain (2018)
- International Journal of Obesity
Warrington NM, Richmond R, Fenstra B, Myhre R, Gaillard R, Paternoster L, Wang CA, Beaumont RN, Das S, Murcia M, Barton SJ, Espinosa A, Thiering E, Atalay M, Pitkanen N, Ntalla I, Jonsson AE, Freathy R, Karhunen V, Tiesler CMT, Allard C, Crawford A, Ring SM, Melbye M, Magnus P, Rivadeneira F, Skotte L, Hansen T, Marsh J, Guxens M, Holloway JW, Grallert H, Jaddoe VWV, Lowe WL, Roumeliotaki T, Hattersley AT, Lindi V, Pahkala K, Panoutsopoulou K, Standl M, Flexeder C, Bouchard L, Nohr E, Marina L, Kogevinas M, Niinikoski H, Dedoussis G, Heinrich J, Reynolds RM, Lakka T, Zeggini E, Raitakari OT, Chatzi L, Inskip HM, Bustamante M, Hivert MF, Jarvelin MR, Sorensen TIA, Pennell C, Felix JF, Jacobsson B, Geller F, Evans DM, Lawlor DA
(A1 Refereed original research article in a scientific journal)
- Success in Achieving the Targets of the 20-Year Infancy-Onset Dietary Intervention: Association With Insulin Sensitivity and Serum Lipids (2018) Laitinen TT, Nuotio J, Juonala M, Niinikoski H, Rovio S, Viikari JSA, Ronnemaa T, Magnussen CG, Jokinen E, Lagstrom H, Jula A, Simell O, Raitakari OT, Pahkala K
(A1 Refereed original research article in a scientific journal)
- Synnynnäisen hypotyreoosin seulonta vastasyntyneiltä kuiva- ja napaverinäytteistä (2018) Anna Linko-Parvinen, Annika Kouki, Johanna Uitto, Riikka Kurkijärvi, Britt-Marie Loo, Tiina Heinonen, Kirsti Näntö-Salonen, Harri Niinikoski, Ilkka Mononen
(A1 Refereed original research article in a scientific journal)
- Vastasyntyneiden aineenvaihduntasairauksien seulonta (2018) Risto Lapatto, Harri Niinikoski, Kirsti Näntö-Salonen, Ilkka Mononen
(A2 Refereed review article in a scientific journal )
- Cardiometabolic Determinants of Carotid and Aortic Distensibility From Childhood to Early Adulthood (2017) Mikola H, Pahkala K, Niinikoski H, Ronnemaa T, Viikari JSA, Jula A, Juonala M, Raitakari OT
(A1 Refereed original research article in a scientific journal)
- Ideal cardiovascular health in childhood-Longitudinal associations with cardiac structure and function: The Special Turku Coronary Risk Factor Intervention Project (STRIP) and the Cardiovascular Risk in Young Finns Study (YFS) (2017)
- International Journal of Cardiology
Laitinen TT, Ruohonen S, Juonala M, Magnussen CG, Mikkila V, Mikola H, Hutri-Kahonen N, Laitinen T, Tossavainen P, Jokinen E, Niinikoski H, Jula A, Viikari JSA, Ronnemaa T, Raitakari OT, Pahkala K
(A1 Refereed original research article in a scientific journal)
- Inhaled Sargramostim Induces Resolution of Pulmonary Alveolar Proteinosis in Lysinuric Protein Intolerance (2017) Laura M. Tanner, Johanna Kurko, Maaria Tringham, Heikki Aho, Juha Mykkänen, Kirsti Näntö-Salonen, Harri Niinikoski, Heikki Lukkarinen
(A1 Refereed original research article in a scientific journal)
- Longitudinal child-oriented dietary intervention: Association with parental diet and cardio-metabolic risk factors. The Special Turku Coronary Risk Factor Intervention Project (2017)
- European Journal of Preventive Cardiology
Jaakkola JM, Pahkala K, Rönnemaa T, Viikari J, Niinikoski H, Jokinen E, Lagström H, Jula A, Raitakari O
(A1 Refereed original research article in a scientific journal)
- Advanced dental maturity of Finnish 6-to 12-yr-old children is associated with high energy intake (2016)
- European Journal of Oral Sciences
Jaasaari P, Tolvanen M, Niinikoski H, Karjalainen S
(A1 Refereed original research article in a scientific journal)
