Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 ORCID identifier: https://orcid.org/0000-0001-9498-364X |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study (2011)
- International Journal of Epidemiology
(A1 Refereed original research article in a scientific journal) - Fetal growth and preterm birth influence cardiovascular risk factors and arterial health in young adults: the Cardiovascular Risk in Young Finns Study (2011)
- Arteriosclerosis, Thrombosis, and Vascular Biology
(A1 Refereed original research article in a scientific journal) - Genetic Variants and Blood Pressure in a Population-Based Cohort The Cardiovascular Risk in Young Finns Study (2011)
- Hypertension
(A1 Refereed original research article in a scientific journal) - Metabolic syndrome in childhood and increased arterial stiffness in adulthood: the Cardiovascular Risk In Young Finns Study (2011)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - Plasma osteopontin is not associated with vascular markers of subclinical atherosclerosis in a population of young adults without symptoms of cardiovascular disease. The Cardiovascular Risk in Young Finns Study (2011)
- Scandinavian Journal of Clinical and Laboratory Investigation
(A1 Refereed original research article in a scientific journal) - Relations between carotid artery distensibility and heart rate variability: The Cardiovascular Risk in Young Finns Study (2011)
- Autonomic Neuroscience: Basic and Clinical
(A1 Refereed original research article in a scientific journal) - Adiponectin is related with carotid artery intima-media thickness and brachial flow-mediated dilatation in young adults-The Cardiovascular Risk in Young Finns Study (2010)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - ADMA concentration changes across the menstrual cycle and during oral contraceptive use. The Cardiovascular Risk in Young Finns Study (2010)
- European Journal of Endocrinology
(A1 Refereed original research article in a scientific journal) - Arterial structure and function after recovery from the metabolic syndrome: the cardiovascular risk in Young Finns Study. (2010)
- Circulation
(A1 Refereed original research article in a scientific journal) - Cardiovascular risk scores in the prediction of subclinical atherosclerosis in young adults: evidence from the cardiovascular risk in a young Finns study (2010)
- European Journal of Cardiovascular Prevention and Rehabilitation
(A1 Refereed original research article in a scientific journal) - Childbearing, Child-Rearing, Cardiovascular Risk Factors, and Progression of Carotid Intima-Media Thickness. The Cardiovascular Risk in Young Finns Study (2010)
- Stroke
(A1 Refereed original research article in a scientific journal) - Early atherosclerosis and cardiac autonomic responses to mental stress: a population-based study of the moderating influence of impaired endothelial function (2010)
- BMC Cardiovascular Disorders
(A1 Refereed original research article in a scientific journal) - Follow-ups of the Cardiovascular Risk in Young Finns Study in 2001 and 2007: Levels and 6-year changes in risk factors (2010)
- Journal of Internal Medicine
(A1 Refereed original research article in a scientific journal) - Genetic Variants and Their Interactions in the Prediction of Increased Pre-Clinical Carotid Atherosclerosis: The Cardiovascular Risk in Young Finns Study (2010)
- PLoS Genetics
(A1 Refereed original research article in a scientific journal) - Increased cancer incidence in acromegaly - a nationwide survey (2010)
- Clinical Endocrinology
(B1 Non-refereed article in a scientific journal) - Influence of age on associations between childhood risk factors and carotid intima-media thickness in adulthood. The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium (2010)
- Circulation
(A1 Refereed original research article in a scientific journal) - Interleukin-18 gene polymorphism and markers of subclinical atherosclerosis. The Cardiovascular Risk in Young Finns Study (2010)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study (2010)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Lifetime Fruit and Vegetable Consumption and Arterial Pulse Wave Velocity in Adulthood: The Cardiovascular Risk in Young Finns Study (2010)
- Circulation
(A1 Refereed original research article in a scientific journal) - Lifetime Risk Factors and Arterial Pulse Wave Velocity in Adulthood. The Cardiovascular Risk in Young Finns Study (2010)
- Hypertension
(A1 Refereed original research article in a scientific journal)