Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 ORCID identifier: https://orcid.org/0000-0001-9498-364X |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Carotid artery intima-media thickness, distensibility and elasticity: population epidemiology and concordance in Australian children aged 11-12 years old and their parents (2019)
- BMJ Open
(A1 Refereed original research article in a scientific journal) - Childhood Exposure to Passive Smoking and Bone Health in Adulthood: The Cardiovascular Risk in Young Finns Study (2019)
- Journal of Clinical Endocrinology and Metabolism
(A1 Refereed original research article in a scientific journal) - Childhood Psychosocial Environment and Adult Cardiac Health: A Causal Mediation Approach (2019)
- American Journal of Preventive Medicine
(A1 Refereed original research article in a scientific journal) - Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts (2019)
- Diabetologia
(A1 Refereed original research article in a scientific journal) - Coronary heart disease risk factor levels in eastern and western Finland from 1980 to 2011 in the cardiovascular risk in Young Finns study (2019)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Cross-sectional associations between Ideal Cardiovascular Health scores and vascular phenotypes in 11- to 12-year-olds and their parents: The Longitudinal Study of Australian Children (2019)
- International Journal of Cardiology
(A1 Refereed original research article in a scientific journal) - CVD risk factors and surrogate markers - Urban-rural differences (2019)
- Scandinavian Journal of Public Health
(A1 Refereed original research article in a scientific journal) - Determinants of left ventricular diastolic function-The Cardiovascular Risk in Young Finns Study (2019)
- Echocardiography
(A1 Refereed original research article in a scientific journal) - Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study (2019)
- Human Molecular Genetics
(A1 Refereed original research article in a scientific journal) - Exome sequencing of Finnish isolates enhances rare-variant association power (2019)
- Nature
(A1 Refereed original research article in a scientific journal) - Genetic architecture of human plasma lipidome and its link to cardiovascular disease (2019)
- Nature Communications
(A1 Refereed original research article in a scientific journal) - Glycoprotein acetyls (GlycA) at 12 months are associated with high-sensitivity C-reactive protein and early life inflammatory immune measures (2019)
- Pediatric Research
(B1 Non-refereed article in a scientific journal) - Health of adults aged 22 to 35 years conceived by assisted reproductive technology (2019)
- Fertility and Sterility
(A1 Refereed original research article in a scientific journal) - IDO activity forecasts obesity in females in 10-year follow-up study: the Cardiovascular Risk in Young Finns study (2019)
- Thrombosis Research
(Other publication) - Inflammatory diet and preclinical cardiovascular phenotypes in 11–12 year-olds and mid-life adults: A cross-sectional population-based study (2019)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - In Memoriam for Gerald Berenson (2019)
- Hypertension
(B1 Non-refereed article in a scientific journal) - Lasten karies ja ientulehdus lisäävät valtimotaudin riskiä aikusiällä (2019)
- Suuhygienisti
(D1 Article in a professional journal) - Longitudinal analysis of risk of Non-Alcoholic Fatty Liver Disease (NAFLD) in adulthood (2019)
- Liver International
(A1 Refereed original research article in a scientific journal) - Long-Term Burden of Increased Body Mass Index from Childhood on Adult Dyslipidemia: The i3C Consortium Study (2019)
- Journal of Clinical Medicine
(A1 Refereed original research article in a scientific journal) - Metabolomics: population epidemiology and concordance in Australian children aged 11-12 years and their parents (2019)
- BMJ Open
(A1 Refereed original research article in a scientific journal)