Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 ORCID identifier: https://orcid.org/0000-0001-9498-364X |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- High birth weight is associated with obesity and increased carotid wall thickness in young adults: The cardiovascular risk in young finns study (2014)
- Arteriosclerosis, Thrombosis, and Vascular Biology
(A1 Refereed original research article in a scientific journal) - Interleukin-6 gene polymorphism, chronic stress and atherosclerosis Interleukin-6-174G>C polymorphism, chronic stress and risk of early atherosclerosis in the Cardiovascular Risk in Young Finns Study (2014)
- Journal of Psychosomatic Research
(A1 Refereed original research article in a scientific journal) - P806 prevalence and determinants of fatty liver in normal weight and overweight young adults. The cardiovascular risk in young finns study (2014)
- Journal of Hepatology
(Other publication) - Preconception metabolic indicators predict gestational diabetes and offspring birthweight (2014)
- Gynecological Endocrinology
(A1 Refereed original research article in a scientific journal) - Prospective Relationship of Change in Ideal Cardiovascular Health Status and Arterial Stiffness: The Cardiovascular Risk in Young Finns Study (2014)
- Journal of the American Heart Association
(A1 Refereed original research article in a scientific journal) - Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque (2014)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Youth Overweight and Metabolic Disturbances in Predicting Carotid Intima-Media Thickness, Type 2 Diabetes, and Metabolic Syndrome in Adulthood – The Cardiovascular Risk in Young Finns Study (2014)
- Diabetes Care
(A1 Refereed original research article in a scientific journal) - Association of Fitness With Vascular Intima-Media Thickness and Elasticity in Adolescence (2013)
- Pediatrics
(A1 Refereed original research article in a scientific journal) - Body-image dissatisfaction is strongly associated with chronic dysphoria (2013)
- Journal of Affective Disorders
(A1 Refereed original research article in a scientific journal) - Childhood lifestyle and clinical determinants of adult ideal cardiovascular health: The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Princeton Follow-up Study. (2013)
- International Journal of Cardiology
(A1 Refereed original research article in a scientific journal) - Childhood Serum Fatty Acid Quality Is Associated with Adult Carotid Artery Intima Media Thickness in Women but Not in Men (2013)
- Journal of Nutrition
(A1 Refereed original research article in a scientific journal) - Cohort Profile: The International Childhood Cardiovascular Cohort (i3C) Consortium (2013)
- International Journal of Epidemiology
(A1 Refereed original research article in a scientific journal) - Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk (2013)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Does childhood nutrition influence adult cardiovascular disease risk?-Insights from the Young Finns Study (2013)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing fetal origins of disease? The Cardiovascular Risk in Young Finns Study (2013)
- American Journal of Clinical Nutrition
(A1 Refereed original research article in a scientific journal) - Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events AtheroRemo Consortium (2013)
- Circulation: Cardiovascular Genetics
(A1 Refereed original research article in a scientific journal) - Higher Maternal Body Mass Index Is Associated with an Increased Risk for Later Type 2 Diabetes in Offspring (2013)
- Journal of Pediatrics
(A1 Refereed original research article in a scientific journal) - Ideal Cardiovascular Health in Adolescence Effect of Lifestyle Intervention and Association With Vascular Intima-Media Thickness and Elasticity (The Special Turku Coronary Risk Factor Intervention Project for Children [STRIP] Study) (2013)
- Circulation
(A1 Refereed original research article in a scientific journal) - Ideal cardiovascular health in young adult populations from the United States, Finland, and Australia and its association with cIMT: the international childhood cardiovascular cohort consortium. (2013)
- Journal of the American Heart Association
(A1 Refereed original research article in a scientific journal) - Main findings from the prospective Cardiovascular Risk in Young Finns Study (2013)
- Current Opinion in Lipidology
(A2 Refereed review article in a scientific journal )