Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 ORCID identifier: https://orcid.org/0000-0001-9498-364X |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults (2017)
- PLoS Genetics
(A1 Refereed original research article in a scientific journal) - Ideal cardiovascular health in childhood-Longitudinal associations with cardiac structure and function: The Special Turku Coronary Risk Factor Intervention Project (STRIP) and the Cardiovascular Risk in Young Finns Study (YFS) (2017)
- International Journal of Cardiology
(A1 Refereed original research article in a scientific journal) - Influence of Child and Adult Elevated Blood Pressure on Adult Arterial Stiffness The Cardiovascular Risk in Young Finns Study (2017)
- Hypertension
(A1 Refereed original research article in a scientific journal) - Intergenerational Continuity in Qualities of the Parent-Child Relationship: Mediating and Moderating Mechanisms (2017)
- Journal of Child and Family Studies
(A1 Refereed original research article in a scientific journal) - Intergenerational transmission of socioeconomic position and ideal cardiovascular health: 32-year follow-up study (2017)
- Health Psychology
(A1 Refereed original research article in a scientific journal) - Interrelationships between indices of longitudinal movement of the common carotid artery wall and the conventional measures of subclinical arteriosclerosis (2017)
- Clinical Physiology and Functional Imaging
(A1 Refereed original research article in a scientific journal) - Low Childhood Cholesterol Absorption Predisposes to Gallstone Disease. The Cardiovascular Risk in Young Finns Study (2017)
- Journal of Pediatric Gastroenterology and Nutrition
(A1 Refereed original research article in a scientific journal) - Low serum adiponectin levels in childhood and adolescence predict increased intima-media thickness in adulthood. The Cardiovascular Risk in Young Finns Study (2017)
- Annals of Medicine
(A1 Refereed original research article in a scientific journal) - Metabolic profiling of fatty liver in young and middle-aged adults: Cross-sectional and prospective analyses of the Young Finns Study (2017)
- Hepatology
(A1 Refereed original research article in a scientific journal) - Positive Psychosocial Factors in Childhood Predicting Lower Risk for Adult Type 2 Diabetes: The Cardiovascular Risk in Young Finns Study, 1980-2012 (2017)
- American Journal of Preventive Medicine
(A1 Refereed original research article in a scientific journal) - Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors - The Cardiovascular Risk in Young Finns Study (2017)
- Circulation: Cardiovascular Genetics
(A1 Refereed original research article in a scientific journal) - Prediction of adulthood obesity using genetic and childhood clinical risk factors in the Cardiovascular Risk in Young Finns Study (2017)
- Circulation: Cardiovascular Genetics
(A1 Refereed original research article in a scientific journal) - Pregnancy complications and later vascular ultrasound measures: A cohort study (2017)
- Pregnancy Hypertension
(A1 Refereed original research article in a scientific journal) - Psychosocial environment in childhood and body mass index growth over 32 years (2017)
- Preventive Medicine
(A1 Refereed original research article in a scientific journal) - Self-rated health as an indicator of ideal cardiovascular health among working-aged women (2017)
- Scandinavian Journal of Primary Health Care
(A1 Refereed original research article in a scientific journal) - Socioeconomic Position Is Associated With Carotid Intima-Media Thickness in Mid-Childhood: The Longitudinal Study of Australian Children (2017)
- Journal of the American Heart Association
(A1 Refereed original research article in a scientific journal) - Socioeconomic status in childhood and C reactive protein in adulthood: a systematic review and meta-analysis (2017)
- Journal of Epidemiology and Community Health
(A2 Refereed review article in a scientific journal ) - The Association Between Social Support, Body Mass Index and Increased Risk of Prediabetes: the Cardiovascular Risk in Young Finns Study (2017)
- International Journal of Behavioral Medicine
(A1 Refereed original research article in a scientific journal) - The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis (2017)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Vascular ultrasound measures before pregnancy and pregnancy complications: A prospective cohort study (2017)
- Hypertension in Pregnancy
(A1 Refereed original research article in a scientific journal)