Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 ORCID identifier: https://orcid.org/0000-0001-9498-364X |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study (2018)
- Journal of the American Heart Association
(A1 Refereed original research article in a scientific journal) - Childhood adiposity, adult adiposity, and the ACE gene insertion/deletion polymorphism: evidence of gene-environment interaction effects on adult blood pressure and hypertension status in adulthoodGenetic polymorphism of sterol transporters in children with future gallstones (2018)
- Journal of Hypertension
(A1 Refereed original research article in a scientific journal) - Childhood cardiorespiratory fitness, muscular fitness and adult measures of glucose homeostasis2018
- Journal of Science and Medicine in SportScandinavian Journal of Public Health
(A1 Refereed original research article in a scientific journal) - Childhood socioeconomic status and lifetime health behaviors: The Young Finns Study (2018)
- International Journal of Cardiology
(A1 Refereed original research article in a scientific journal) - Distinct child-to-adult body mass index trajectories are associated with different levels of adult cardiometabolic risk (2018)
- European Heart Journal
(A1 Refereed original research article in a scientific journal) - Early life determinants of cardiovascular health in adulthood. The Australian Aboriginal Birth Cohort study (2018)
- International Journal of Cardiology
(A1 Refereed original research article in a scientific journal) - Education as a moderator of genetic risk for higher body mass index: prospective cohort study from childhood to adulthoodIs the Association Between Depressive Symptoms and Glucose Bidirectional? A Population-Based Study2018
- International Journal of ObesityHealth Psychology
(A1 Refereed original research article in a scientific journal) - Fatty liver is associated with blood pathways of inflammatory response, immune system activation and prothrombotic state in Young Finns Study (2018)
- Scientific ReportsDuodecim
(A1 Refereed original research article in a scientific journal) - (2018)
- Digestive and Liver DiseaseDuodecim
(A1 Refereed original research article in a scientific journal) - Geographic origin as a determinant of left ventricular mass and diastolic function – the Cardiovascular Risk in Young Finns Study (2018)
(A1 Refereed original research article in a scientific journal) - Impact of Ideal Cardiovascular Health in Childhood on the Retinal Microvasculature in Midadulthood: Cardiovascular Risk in Young Finns Study (2018)
- Journal of the American Heart Association
(A1 Refereed original research article in a scientific journal) - Impact of Lipid Measurements in Youth in Addition to Conventional Clinic-Based Risk Factors on Predicting Preclinical Atherosclerosis in Adulthood: The International Childhood Cardiovascular Cohort (i3C) Consortium (2018)
- CirculationMedicine and Science in Sports and Exercise
(A1 Refereed original research article in a scientific journal) - Influence of cardiovascular risk factors on longitudinal motion of the common carotid artery wall2018
- AtherosclerosisHypertension
(A1 Refereed original research article in a scientific journal) - (2018)
(A1 Refereed original research article in a scientific journal) - Lapsuuden elintavat ja diabeteksen ehkäisy: kuinka panostaa tuleviin sukupolviin? (2018)
(D1 Article in a professional journal) - Lihavuuden lääkehoito (2018)
(A2 Refereed review article in a scientific journal ) - Low childhood high density lipoprotein cholesterol levels and subsequent risk for chronic inflammatory bowel disease (2018)
- Digestive and Liver Disease
(A1 Refereed original research article in a scientific journal) - Neighbourhood socioeconomic disadvantage, risk factors, and diabetes from childhood to middle age in the Young Finns Study: a cohort study (2018)
- Lancet Public Health
(A1 Refereed original research article in a scientific journal) - Physical Inactivity from Youth to Adulthood and Risk of Impaired Glucose Metabolism (2018)
(A1 Refereed original research article in a scientific journal) - Pulse Wave Velocity Predicts the Progression of Blood Pressure and Development of Hypertension in Young Adults (2018)
(A1 Refereed original research article in a scientific journal)