Markus Juonala
 Professor


mataju@utu.fi

+358 29 450 2754

+358 50 478 3572




ORCID identifierhttps://orcid.org/0000-0001-9498-364X





Areas of expertise
Internal medicine; endocrinology; cardiovascular risk

Research community or research topic
Cardiovascular epidemiology, Young Finns Study, i3c consortium

Biography

Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI). 

His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal). 



Research

Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.

 




Teaching

Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs

Special interest areas: Acute internal medicine, endocrinology, lipidology

  



Publications
  
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  • Dietary Pattern Trajectories from Youth to Adulthood and Adult Risk of Impaired Fasting Glucose: A 31-year Cohort Study  (2021)  
    • Journal of Clinical Endocrinology and Metabolism
     Wu Feitong, Pahkala Katja, Juonala Markus, Rovio Suvi P., Sabin Matthew A., Rönnemaa Tapani, Buscot Marie-Jeanne, Smith Kylie J., Männistö Satu, Jula Antti, Lehtimäki Terho, Hutri-Kähönen Nina, Kähönen Mika, Laitinen Tomi, Viikari Jorma S.A., Raitakari Olli T., Magnussen Costan G.
    (
    A1 Refereed original research article in a scientific journal)


  • Diet quality trajectories and cardiovascular phenotypes/metabolic syndrome risk by 11-12 years  (2021)  
    • International Journal of Obesity
     Kerr Jessica A, Liu Richard S, Gasser Constantine E, Mensah Fiona K, Burgner David, Lycett Kate, Gillespie Alanna N, Juonala Markus, Clifford Susan A, Olds Tim, Saffery Richard, Gold Lisa, Liu Mengjiao, Azzopardi Peter, Edwards Ben, Dwyer Terence, Wake Melissa
    (
    A1 Refereed original research article in a scientific journal)


  • Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts  (2021)  
    • Scientific Reports
     Laaksonen Jaakko, Mishra Pashupati P., Seppälä Ilkka, Lyytikäinen Leo-Pekka, Raitoharju Emma, Mononen Nina, Lepistö Maija, Almusa Henrikki, Ellonen Pekka, Hutri-Kähönen Nina, Juonala Markus, Raitakari Olli, Kähönen Mika, Salonen Jukka T., Lehtimäki Terho
    (
    A1 Refereed original research article in a scientific journal)


  • Fatty liver index predicts incident risk of prediabetes, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD)  (2021)  
    • Annals of Medicine
     Cuthbertson Daniel J., Koskinen Juha, Brown Emily ,Magnussen Costan G. Hutri-Kähönen Nina,Sabin Matthew, Tossavainen Päivi , Jokinen Eero, Laitinen Tomi, Viikari Jorma, Raitakari Olli T, Juonala Markus
    (
    A1 Refereed original research article in a scientific journal)


  • Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries  (2021)  
    • Nature Communications
     Gharahkhani Puya, Jorgenson Eric, Hysi Pirro, Khawaja Anthony P., Pendergrass Sarah, Han Xikun, Ong Jue Sheng, Hewitt Alex W., Segrè Ayellet V., Rouhana John M., Hamel Andrew R., Igo Jr Robert P., Choquet Helene, Qassim Ayub, Josyula Navya S., Bailey Jessica N. Cooke, Bonnemaijer Pieter W. M., Iglesias Adriana, Siggs Owen M., Young Terri L., Vitart Veronique, Thiadens Alberta A. H. J., Karjalainen Juha, Uebe Steffen, Melles Ronald B., Nair K. Saidas, Luben Robert, Simcoe Mark, Amersinghe Nishani, Cree Angela J., Hohn Rene, Poplawski Alicia, Chen Li Jia, Rong Shi-Song, Aung Tin, Eranga Nishanthie Vithana, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team, Tamiya Gen, Shiga Yukihiro, Yamamoto Masayuki, Nakazawa Toru, Currant Hannah, Birney Ewan, Wang Xin, Auton Adam, Lupton Michelle K., Martin Nicholas G., Ashaye Adeyinka, Olawoye Olusola, Williams Susan E., Akafo Stephen, Ramsay Michele, Hashimoto Kazuki, Kamatani Yoichiro, Akiyama Masato, Momozawa Yukihide, Foster Paul J., Khaw Peng T., Morgan James E., Strouthidis Nicholas G., Kraft Peter, Kang Jae H., Pang Chi Pui, Pasutto Francesca, Mitchell Paul, Lotery Andrew J., Palotie Aarno, van Duijn Cornelia, Haines Jonathan L., Hammond Chris, Pasquale Louis R., Klaver Caroline C. W., Hauser Michael, Khor Chiea Chuen, Mackey David A., Kubo Michiaki, Cheng Ching-Yu, Craig Jamie E., MacGregor Stuart, Wiggs Janey L.; FinnGen Study
    (
    A1 Refereed original research article in a scientific journal)


  • Hyperkolesterolemian uudet hoitosuositukset  (2021)  
    • Erikoislääkäri
     Nelimarkka Lassi, Juonala Markus
    (
    D1 Article in a professional journal)


  • IDO activity forecasts obesity in males and premenopausal females in a 10-year follow-up study:The Cardiovascular Risk in Young Finns Study  (2021)  
    • Atherosclerosis
     Niinisalo Petri, Raitakari Olli T, Kähönen Mika, Hurme Mikko, Lehtimäki Terho, Magnussen Costan, Viikari Jorma, Juonala Markus, Kaaja Risto
    (
    A1 Refereed original research article in a scientific journal)


  • Influence of early-life body mass index and systolic blood pressure on left ventricle in adulthood - the Cardiovascular Risk in Young Finns Study  (2021)  
    • Annals of Medicine
     Heiskanen Jarkko S, Hernesniemi Jussi A, Ruohonen Saku, Hutri-Kähönen Nina, Kähonen Mika, Jokinen Eero, Tossavainen Päivi, Kallio Merja, Laitinen Tomi, Lehtimäki Terho, Viikari Jorma, Juonala Markus, Nevalainen Jaakko, Raitakari Olli T
    (
    A1 Refereed original research article in a scientific journal)


  • Influence of early life risk factors and lifestyle on systemic vascular resistance in later adulthood: the cardiovascular risk in young Finns study  (2021)  
    • Blood Pressure
     Kähönen Emilia, Aatola Heikki, Lehtimaki Terho, Haarala Atte, Sipilä Kalle, Juonala Markus, Raitakari Olli T, Kähönen Mika, Hutri-Kähönen Nina
    (
    A1 Refereed original research article in a scientific journal)


  • Influential Periods in Longitudinal Clinical Cardiovascular Health Scores   (2021)  
    • American Journal of Epidemiology
     Krefman Amy E, Labarthe Darwin, Greenland Philip, Pool Lindsay, Aguayo Liliana, Juonala Markus, Kähönen Mika, Lehtimäki Terho, Day R Sue, Bazzano Lydia, Muggeo Vito M R, Van Horn Linda, Liu Lei, Webber Larry S, Pahkala Katja, Laitinen Tomi T, Raitakari Olli, Lloyd-Jones Donald M, Allen Norrina B
    (
    A1 Refereed original research article in a scientific journal)



Last updated on 12/07/2023 12:00:11 PM