MD/PhD Olli Raitakari - UTU Tutkimustietojärjestelmä

Olli Raitakari
MD/PhD

- professori,
sydäntutkimuskeskus (väestötutkimuskeskus)
- ,
InFLAMES Lippulaiva (lääketieteellinen tiedekunta)

olli.raitakari@utu.fi

+358 29 450 2304

Kiinamyllynkatu 10

Turku

ORCID-tunniste: https://orcid.org/0000-0001-9365-3702

10_representative_publications.pdf

Asiantuntijuusalueet

cardiovascular and metabolic diseases; risk factors; vascular epidemiology; genetic epidemiology; epidemiology; dietary intervention; cohort studies; follow-up studies

Biografia

EDUCATION AND DEGREES

2001   Docent in Clinical Physiology
1997-1999  Postdoc training, Royal Prince Alfred Hospital, Sydney, Australia
1997   Docent in Epidemiology
1996   Specialist in Clinical Physiology
1995   Doctorate, PhD
1989   Licentiate in Medicine, MD

CURRENT POSITIONS

2017- Professor in Cardiovascular Medicine, Director of the Research Centre of Applied and
Preventive Cardiovascular Medicine, University of Turku, Finland

PAST POSITIONS

2012-2016 Academy Professor, University of Turku

2007-2016 Professor in Cardiovascular Medicine (part time), University of Turku

2007-2008 Senior Scientist Grant, Academy of Finland

2004-2016 Chief Physician, Department of Clinical Physiology and Nuclear Medicine, Turku
University Hospital (leave of absence 2012-2016)

2002-2004 Consultant in Clinical Physiology and Nuclear Medicine, Turku University Hospital

2002 (1 mo) Head of Nuclear Medicine Department, Turku University Hospital

2000-2003 (3 mo) Head of Clinical Physiology Department, Turku University Hospital

2000-2005 Senior Fellow Post, Academy of Finland

1998-2000 Postdoctoral Research Post, Academy of Finland

1996-1997 Consultant in Clinical Physiology, Turku University Hospital

1991-1996 Positions as Resident in Clinical Chemistry, Nuclear Medicine, and Clinical
Physiology, Turku University Hospital

1988-1990 Positions as General Practioner and Resident in Internal Medicine or Surgery

Tutkimus

Evidence suggest that many non-communicable disease outcomes have roots in childhood and may even stem of adverse ancestral exposures. Improved knowledge how various ancestral and early-life exposures lead to adult disease outcomes is essential in developing better preventive practices and policies that lead to improved public health. My mission has been to contribute to this knowledge-base by working in epidemiologic cohort studies with follow-up from childhood to adulthood. I am the Principal Investigator of the Cardiovascular Risk in Young Finns Study (YFS), the largest study in Europe with a follow-up of cardiovascular risk factors from childhood to adulthood. I am also the Director of the STRIP Study, which is a leading long-term pediatric dietary intervention study testing the hypothesis that modifying the fat quality diet will have beneficial effects on cardiovascular risk early in life. During the past years, I have organized several field studies in these cohorts, and introduced novel technologies, such as imaging studies, genetic epidemiology methods and metabolomics approaches in these unique population resources. Our research has contributed to the understanding of pre-clinical development of atherosclerosis in children and young adults, including the effects of diet, life-style, metabolic risk factors, psychological traits and psychosocial factors, inflammation, hormones and genetic markers. For example, by applying non-invasive imaging methods in the Young Finns Study, we have demonstrated that exposure to adverse lipids, elevated blood pressure and obesity in childhood is related to atherosclerosis development in adulthood (JAMA 2003). Subsequent work stemmed from this initial observation has led to numerous original publications that have shown in detail how exposure to a large range of aetiogenic factors early in life contribute to the development of cardio-metabolic outcomes in adulthood. For example, by pooling international i3C Consortium data, we have demonstrated that overweight or obese children who became non-obese by adulthood had similar risks of many cardio-metabolic adult outcomes as individuals who were never obese (NEJM 2011). Thus, the results of our studies have clearly demonstrated that individual’s exposure to various stressors in early life is contributing to his/her adult phenotype and disease risk. The results have had significant impact on preventive practices. As a concrete demonstration of the international recognition and impact of my team’s work, many of our studies are widely cited in all updated paediatric guidelines on cardiovascular prevention both in Europe and in US.

Julkaisut

34/51

Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humans (2015)
- Arteriosclerosis, Thrombosis, and Vascular Biology
Rinne P, Ahola-Olli A, Nuutinen S, Koskinen E, Kaipio K, Eerola K, Juonala M, Kahonen M, Lehtimaki T, Raitakari OT, Savontaus E
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Determinants of serum 25(OH)D concentration in young and middle-aged adults. The Cardiovascular Risk in Young Finns Study (2015)
- Annals of Medicine
Atte J. W. Voipio, Katja A. Pahkala, Jorma S. A. Viikari, Vera Mikkilä, Costan G. Magnussen, Nina Hutri-Kähönen, Mika Kähönen, Terho Lehtimäki, Satu Männistö, Britt-Marie Loo, Antti Jula, Jukka Marniemi, Markus Juonala, Olli T. Raitakari
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents (2015)
- Diabetes
Qi QB, Downer MK, Kilpelainen TO, Taal HR, Barton SJ, Ntalla I, Standl M, Boraska V, Huikari V, Kiefte-de Jong JC, Korner A, Lakka TA, Liu GF, Magnusson J, Okuda M, Raitakari O, Richmond R, Scott RA, Bailey MES, Scheuermann K, Holloway JW, Inskip H, Isasi CR, Mossavar-Rahmani Y, Jaddoe VWV, Laitinen J, Lindi V, Melen E, Pitsiladis Y, Pitkanen N, Snieder H, Heinrich J, Timpson NJ, Wang T, Yuji H, Zeggini E, Dedoussis GV, Kaplan RC, Wylie-Rosett J, Loos RJF, Hu FB, Qi L
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Directional dominance on stature and cognition in diverse human populations (2015)
- Nature
Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang WH, Okada Y, Stancakova A, Faul JD, Zhao W, Bartz TM, Concas MP, Franceschini N, Enroth S, Vitart V, Trompet S, Guo XQ, Chasman DI, O'Connel JR, Corre T, Nongmaithem SS, Chen Y, Mangino M, Ruggiero D, Michela T, Farmaki AE, Kacprowski T, Bjonnes A, van der Spek A, Wu Y, Giri AK, Yanek LR, Wang LH, Hofer E, Rietveld CA, McLeod O, Cornelis MC, Pattaro C, Verweij N, Baumbach C, Abdellaoui A, Warren HR, Vuckovic D, Mei H, Bouchard C, Perry JRB, Cappellani S, Mirza SS, Benton MC, Broeckel U, Medland SE, Lind P, Malerba G, Drong A, Yengo L, Bielak LF, Zhi DG, van der Most PJ, Shriner D, Magi R, Hemani G, Karaderi T, Wang ZM, Liu T, Demuth I, Zhao JH, Meng WH, Lataniotis L, van der Laan SW, Bradfield JP, Wood AR, Bonnefond A, Ahluwalia TS, Hall L, Salvi E, Yazar S, Carstensen L, de Haan HG, Abney M, Afzal U, Allison MA, Amin N, Asselbergs FW, Bakker SJL, Barr RG, Baumeister SE, Benjamin DJ, Bergmann S, Boerwinkle E, Bottinger EP, Campbell A, Chakravarti A, Chan YL, Chanock SJ, Chen C, Chen YDI, Collins FS, Connell J, Correa A, Cupples LA, Smith GD, Davies G, Dorr M, Ehret G, Ellis SB, Feenstra B, Feitosa MF, Ford I, Fox CS, Frayling TM, Friedrich N, Geller F, Scotland G, Gillham-Nasenya I, Gottesman O, Graff M, Grodstein F, Gu C, Haley C, Hammond CJ, Harris SE, Harris TB, Hastie ND, Heard-Costa NL, Heikkila K, Hocking LJ, Homuth G, Hottenga JJ, Huang JY, Huffman JE, Hysi PG, Ikram MA, Ingelsson E, Joensuu A, Johansson A, Jousilahti P, Jukema JW, Kahonen M, Kamatani Y, Kanoni S, Kerr SM, Khan NM, Koellinger P, Koistinen HA, Kooner MK, Kubo M, Kuusisto J, Lahti J, Launer LJ, Lea RA, Lehne B, Lehtimaki T, Liewald DCM, Lind L, Loh M, Lokki ML, London SJ, Loomis SJ, Loukola A, Lu YC, Lumley T, Lundqvist A, Mannisto S, Marques-Vidal P, Masciullo C, Matchan A, Mathias RA, Matsuda K, Meigs JB, Meisinger C, Meitinger T, Menni C, Mentch FD, Mihailov E, Milani L, Montasser ME, Montgomery G, Morrison A, Myers RH, Nadukuru R, Navarro P, Nelis M, Nieminen MS, Nolte IM, O'Connor GT, Ogunniyi A, Padmanabhan S, Palmas WR, Pankow JS, Patarcic I, Pavani F, Peyser PA, Pietilainen K, Poulter N, Prokopenko I, Ralhan S, Redmond P, Rich SS, Rissanen H, Robino A, Rose LM, Rose R, Sala C, Salako B, Salomaa V, Sarin AP, Saxena R, Schmidt H, Scott LJ, Scott WR, Sennblad B, Seshadri S, Sever P, Shrestha S, Smith BH, Smith JA, Soranzo N, Sotoodehnia N, Southam L, Stanton AV, Stathopoulou MG, Strauch K, Strawbridge RJ, Suderman MJ, Tandon N, Tang ST, Taylor KD, Tayo BO, Toglhofer AM, Tomaszewski M, Tsernikova N, Tuomilehto J, Uitterlinden AG, Vaidya D, Vlieg AV, van Setten J, Vasankari T, Vedantam S, Vlachopoulou E, Vozzi D, Vuoksimaa E, Waldenberger M, Ware EB, Wentworth-Shields W, Whitfield JB, Wild S, Willemsen G, Yajnik CS, Yao J, Zaza G, Zhu XF, Salem RM, Melbye M, Bisgaard H, Samani NJ, Cusi D, Mackey DA, Cooper RS, Froguel P, Pasterkamp G, Grant SFA, Hakonarson H, Ferrucci L, Scott RA, Morris AD, Palmer CNA, Dedoussis G, Deloukas P, Bertram L, Lindenberger U, Berndt SI, Lindgren CM, Timpson NJ, Tonjes A, Munroe PB, Sorensen TIA, Rotimi CN, Arnett DK, Oldehinkel AJ, Kardia SLR, Balkau B, Gambaro G, Morris AP, Eriksson JG, Wright MJ, Martin NG, Hunt SC, Starr JM, Deary IJ, Griffiths LR, Tiemeier H, Pirastu N, Kaprio J, Wareham NJ, Peerusse L, Wilson JG, Girotto G, Caulfield MJ, Raitakari O, Boomsma DI, Gieger C, van der Harst P, Hicks AA, Kraft P, Sinisalo J, Knekt P, Johannesson M, Magnusson PKE, Hamsten A, Schmidt R, Borecki IB, Vartiainen E, Becker DM, Bharadwaj D, Mohlke KL, Boehnke M, van Duijn CM, Sanghera DK, Teumer A, Zeggini E, Metspalu A, Gasparini P, Ulivi S, Ober C, Toniolo D, Rudan I, Porteous DJ, Ciullo M, Spector TD, Hayward C, Dupuis J, Loos RJF, Wright AF, Chandak GR, Vollenweider P, Shuldiner AR, Ridker PM, Rotter JI, Sattar N, Gyllensten U, North KE, Pirastu M, Psaty BM, Weir DR, Laakso M, Gudnason V, Takahashi A, Chambers JC, Kooner JS, Strachan DP, Campbell H, Hirschhorn JN, Perola M, Polasek O, Wilson JF
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation (2015)
- PLoS Genetics
Horikoshi M, Magi R, van de Bunt M, Surakka I, Sarin AP, Mahajan A, Marullo L, Thorleifsson G, Hagg S, Hottenga JJ, Ladenvall C, Ried JS, Winkler TW, Willems SM, Pervjakova N, Esko T, Beekman M, Nelson CP, Willenborg C, Wiltshire S, Ferreira T, Fernandez J, Gaulton KJ, Steinthorsdottir V, Hamsten A, Magnusson PKE, Willemsen G, Milaneschi Y, Robertson NR, Groves CJ, Bennett AJ, Lehtimaki T, Viikari JS, Rung J, Lyssenko V, Perola M, Heid IM, Herder C, Grallert H, Muller-Nurasyid M, Roden M, Hypponen E, Isaacs A, van Leeuwen EM, Karssen LC, Mihailov E, Houwing-Duistermaat JJ, de Craen AJM, Deelen J, Havulinna AS, Blades M, Hengstenberg C, Erdmann J, Schunkert H, Kaprio J, Tobin MD, Samani NJ, Lind L, Salomaa V, Lindgren CM, Slagboom PE, Metspalu A, van Duijn CM, Eriksson JG, Peters A, Gieger C, Jula A, Groop L, Raitakari OT, Power C, Penninx BWJH, de Geus E, Smit JH, Boomsma DI, Pedersen NL, Ingelsson E, Thorsteinsdottir U, Stefansson K, Ripatti S, Prokopenko I, McCarthy MI, Morris AP; ENGAGE Consortium
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Distensibility of the Aorta and Carotid Artery and Left Ventricular Mass From Childhood to Early Adulthood. (2015)
- Hypertension
Hanna Mikola, Katja Pahkala, Tapani Rönnemaa, Jorma S.A. Viikari, Harri Niinikoski, Eero Jokinen, Pia Salo, Olli Simell, Markus Juonala, Olli T. Raitakari
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: The Cardiovascular Risk in Young Finns Study (2015)
- Atherosclerosis
Burgner DP, Sabin MA, Magnussen CG, Cheung M, Sun C, Kahonen M, Hutri-Kahonen N, Lehtimaki T, Jokinen E, Laitinen T, Viikari JSA, Raitakari OT, Juonala M
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns Study (2015)
- Journal of Hypertension
Juonala M, Cheung MMH, Sabin MA, Burgner D, Skilton MR, Kahonen M, Hutri-Kahonen N, Lehtimaki T, Jula A, Laitinen T, Jokinen E, Taittonen L, Tossavainen P, Viikari JSA, Magnussen CG, Raitakari OT
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants (2015)
- Lancet Diabetes and Endocrinology
Danaei G, Fahimi S, Lu Y, Zhou B, Hajifathalian K, Di Cesare M, Lo WC, Reis-Santos B, Cowan MJ, Shaw JE, Bentham J, Lin JK, Bixby H, Magliano D, Bovet P, Miranda JJ, Khang YH, Stevens GA, Riley LM, Ali MK, Ezzati M, Abdeen ZA, Kadir KA, Abu-Rmeileh NM, Acosta-Cazares B, Aekplakorn W, Aguilar-Salinas CA, Ahmadvand A, Al Nsour M, Alkerwi A, Amouyel P, Andersen LB, Anderssen SA, Andrade DS, Anjana RM, Aounallah-Skhiri H, Aris T, Arlappa N, Arveiler D, Assah FK, Avdicova M, Balakrishna N, Bandosz P, Barbagallo CM, Barcelo A, Batieha AM, Baur LA, Ben Romdhane H, Bernabe-Ortiz A, Bhargava SK, Bi YF, Bjerregaard P, Bjorkelund C, Blake M, Blokstra A, Bo S, Boehm BO, Boissonnet CP, Bovet P, Brajkovich I, Breckenkamp J, Brewster LM, Brian GR, Bruno G, Bugge A, de Leon AC, Can G, Candido APC, Capuano V, Carvalho MJ, Casanueva FF, Caserta CA, Castetbon K, Chamukuttan S, Chaturvedi N, Chen CJ, Chen F, Chen S, Cheng CY, Chetrit A, Chiou ST, Cho Y, Chudek J, Cifkova R, Claessens F, Concin H, Cooper C, Cooper R, Costanzo S, Cottel D, Cowell C, Crujeiras AB, D'Arrigo G, Dallongeville J, Dankner R, Dauchet L, de Gaetano G, De Henauw S, Deepa M, Dehghan A, Dhana K, Di Castelnuovo AF, Djalalinia S, Doua K, Drygas W, Du Y, Egbagbe EE, Eggertsen R, El Ati J, Elosua R, Erasmus RT, Erem C, Ergor G, Eriksen L, la Penaa JED, Fall CH, Farzadfar F, Felix-Redondo FJ, Ferguson TS, Fernandez-Berges D, Ferrari M, Ferreccio C, Finn JD, Foger B, Foo LH, Fouad HM, Francis DK, Franco MDC, Franco OH, Frontera G, Furusawa T, Gaciong Z, Galbarczyk A, Garnett SP, Gaspoz JM, Gasull M, Gates L, Geleijnse JM, Ghasemain A, Giampaoli S, Gianfagna F, Giovannelli J, Gross MG, Rivas JPG, Gorbea MB, Gottrand F, Grant JF, Grodzicki T, Grontved A, Gruden G, Gu DF, Guan OP, Guerrero R, Guessous I, Guimaraes AL, Gutierrez L, Hardy R, Kumar RH, He J, Heidemann C, Hihtaniemi IT, Ho SY, Ho SC, Hofman A, Russo ARV, Hormiga CM, Horta BL, Houti L, Hussieni AS, Huybrechts I, Hwalla N, Iacoviello L, Iannone AG, Ibrahim MM, Ikeda N, Ikram MA, Irazola VE, Islam M, Iwasaki M, Jacobs JM, Jafar T, Jasienska G, Jiang CQ, Jonas JB, Joshi P, Kafatos A, Kalter-Leibovici O, Kasaeian A, Katz J, Kaur P, Kavousi M, Kelishadi R, Kengne AP, Kersting M, Khader YS, Khang YH, Kiechl S, Kim J, Kiyohara Y, Kolsteren P, Korrovits P, Koskinen S, Kratzer W, Kromhout D, Kula K, Kurjata P, Kyobutungi C, Lachat C, Laid Y, Lam TH, Landrove O, Lanska V, Lappas G, Laxmaiah A, Leclercq C, Lee J, Lee J, Lehtimaaki T, Lekhraj R, Leon-Munoz LM, Li Y, Lim WY, Lima-Costa MF, Lin HH, Lin X, Lissner L, Lorbeer R, Lozano JE, Lundqvist A, Lytsy P, Ma G, Machado-Coelho GLL, Machi S, Maggi S, Magliano D, Makdisse M, Rao KM, Manios Y, Manzato E, Margozzini P, Marques-Vidal P, Martorell R, Masoodi SR, Matsha TE, Mbanya JCN, McFarlane SR, McGarvey ST, McLachlan S, McNulty BA, Mediene-Benchekor S, Meirhaeghe A, Menezes AMB, Merat S, Meshram II, Mi J, Miquel JF, Miranda JJ, Mohamed MK, Mohammad K, Mohan V, Yusoff MFM, Moller NC, Molnar D, Mondo CK, Moreno LA, Morgan K, Moschonis G, Mossakowska M, Mostafa A, Mota J, Muiesan ML, Muller-Nurasyid M, Mursu J, Nagel G, Namesna J, Nang EEK, Nangia VB, Navarrete-Munoz EM, Ndiaye NC, Nervi F, Nguyen ND, Nieto-Martinez RSE, Ning G, Ninomiya T, Noale M, Noto D, Ochoa-Aviles AM, Oh K, Onat A, Osmond C, Otero JA, Palmieri L, Panda-Jonas S, Panza F, Parsaeian M, Peixoto SV, Pereira AC, Peters A, Peykari N, Pilav A, Pitakaka F, Piwonska A, Piwonski J, Plans-Rubio P, Porta M, Portegies MLP, Poustchi H, Pradeepa R, Price JF, Punab M, Qasrawi RF, Qorbani M, Raitakari O, Rao SR, Ramachandran A, Ramos R, Rampal S, Rathmann W, Redon J, Reganit PFM, Rigo F, Robinson SM, Robitaille C, Rodriguez LA, Rodriguez-Artalejo F, Rodriguez-Perez MDC, Rojas-Martinez R, Romaguera D, Rosengren A, Rubinstein A, Rui O, Ruiz-Betancourt BS, Rutkowski M, Sabanayagam C, Sachdev HS, Saidi O, Sakarya S, Salanave B, Salonen JT, Salvetti M, Sanchez-Abanto J, Nunes R, Santos R, Sardinha LB, Scazufca M, Schargrodsky H, Scheidt-Nave C, Shaw JE, Shibuya K, Shin Y, Shiri R, Siantar R, Sibai AM, Simon M, Simons J, Simons LA, Sjostrom M, Slowikowska-Hilczer J, Slusarczyk P, Smeeth L, Snijder MB, Solfrizzi V, Sonestedt E, Soumare A, Staessen JA, Steene-Johannessen J, Stehle P, Stein AD, Stessman J, Stockl D, Stokwiszewski J, Strufaldi MW, Sun CA, Sundstrom J, Suriyawongpaisal P, Sy RG, Tai ES, Tarawneh M, Tarqui-Mamani CB, Thijs L, Tolstrup JS, Topbas M, Torrent M, Traissac P, Trinh OTH, Tulloch-Reid MK, Tuomainen TP, Turley ML, Tzourio C, Ueda P, Ukoli FM, Ulmer H, Valdivia G, Van Valkengoed IGM, Vanderschueren D, Vanuzzo D, Vega T, Velasquez-Melendez G, Veronesi G, Verschuren M, Vioque J, Virtanen J, Visvikis-Siest S, Viswanathan B, Vollenweider P, Voutilainen S, Wade AN, Wagner A, Walton J, Mohamud WNW, Wang MD, Wang YX, Wannamethee SG, Weerasekera D, Whincup PH, Widhalm K, Wiecek A, Wilks RJ, Willeit J, Wojtyniak B, Wong TY, Woo J, Woodward M, Wu AG, Wu FC, Wu SL, Xu HQ, Yang XG, Ye XW, Yoshihara A, Younger-Coleman NO, Zambon S, Zargar AH, Zdrojewski T, Zhao WH, Zheng YF
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Exposure to parental smoking in childhood is associated with increased risk of carotid atherosclerotic plaque in adulthood: the Cardiovascular Risk in Young Finns Study (2015)
- Circulation
West HW, Juonala M, Gall SL, Kähönen M, Laitinen T, Taittonen L, Viikari JS, Raitakari OT, Magnussen CG
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Factors associated with six-year weight change in young and middle-aged adults in the Young Finns Study (2015)
- Scandinavian Journal of Clinical and Laboratory Investigation
Kaikkonen JE, Mikkila V, Juonala M, Keltikangas-Jarvinen L, Hintsanen M, Pulkki-Raback L, Viikari JSA, Kahonen M, Lehtimaki T, Telama R, Raitakari OT
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C (2015)
- npj aging and mechanisms of disease
van Leeuwen EM, Huffman JE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Feitosa MF, Duan Q, Schraut KE, Navarro P, van Vliet-Ostaptchouk JV, Zhu G, Mbarek H, Trompet S, Verweij N, Lyytikainen LP, Deelen J, Nolte IM, van der Laan SW, Davies G, Vermeij-Verdoold AJM, van Oosterhout AALJ, Vergeer-Drop JM, Arking DE, Trochet H, Scotland G, Medina-Gomez C, Rivadeneira F, Uitterlinden AG, Dehghan A, Franco OH, Sijbrands EJ, Hofman A, White CC, Mychaleckyj JC, Peloso GM, Swertz MA, Willemsen G, de Geus EJ, Milaneschi Y, Penninx BWJH, Ford I, Buckley BM, de Craen AJM, Starr JM, Deary IJ, Pasterkamp G, Oldehinkel AJ, Snieder H, Slagboom PE, Nikus K, Kahonen M, Lehtimaki T, Viikari JS, Raitakari OT, van der Harst P, Jukema JW, Hottenga JJ, Boomsma DI, Whitfield JB, Montgomery G, Martin NG, Polasek O, Vitart V, Hayward C, Kolcic I, Wright AF, Rudan I, Joshi PK, Wilson JF, Lange LA, Wilson JG, Gudnason V, Harris TB, Morrison AC, Borecki IB, Rich SS, Padmanabhan S, Psaty BM, Rotter JI, Smith BH, Boerwinkle E, Cupples LA, van Duijn C
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits (2015)
- Diabetes Care
Dashti HS, Follis JL, Smith CE, Tanaka T, Garaulet M, Gottlieb DJ, Hruby A, Jacques PF, Kiefte-de Jong JC, Lamon-Fava S, Scheer FAJL, Bartz TM, Kovanen L, Wojczynski MK, Frazier-Wood AC, Ahluwalia TS, Perala MM, Jonsson A, Muka T, Kalafati IP, Mikkila V, Ordovas JM; for the CHARGE Nutrition Study Group
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Genetic analysis for a shared biological basis between migraine and coronary artery disease (2015)
- Neurology-Genetics
Winsvold BS, Nelson CP, Malik R, Gormley P, Anttila V, Vander Heiden J, Elliott KS, Jacobsen LM, Palta P, Amin N, de Vries B, Hämäläinen E, Freilinger T, Ikram MA, Kessler T, Koiranen M, Ligthart L, McMahon G, Pedersen LM, Willenborg C, Won HH, Olesen J, Artto V, Assimes TL, Blankenberg S, Boomsma DI, Cherkas L, Davey Smith G, Epstein SE, Erdmann J, Ferrari MD, Göbel H, Hall AS, Jarvelin MR, Kallela M, Kaprio J, Kathiresan S, Lehtimäki T, McPherson R, März W, Nyholt DR, O'Donnell CJ, Quaye L, Rader DJ, Raitakari O, Roberts R, Schunkert H, Schürks M, Stewart AF, Terwindt GM, Thorsteinsdottir U, van den Maagdenberg AM, van Duijn C, Wessman M, Kurth T, Kubisch C, Dichgans M, Chasman DI, Cotsapas C, Zwart JA, Samani NJ, Palotie A
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Genetic studies of body mass index yield new insights for obesity biology (2015)
- Nature
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Felix R, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan JA, Magi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman AK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham L, Buyske S, Demirkan A, Deng GH, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stancakova A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Settee J, Van Vliet-Ostaptchouk JV, Wang ZM, Yengo L, Zhang WH, Isaacs A, Albrecht E, Arnlov J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Bluher M, Bohringer 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Gene x dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry (2015)
- Human Molecular Genetics
Nettleton JA, Follis JL, Ngwa JS, Smith CE, Ahmad S, Tanaka T, Wojczynski MK, Voortman T, Lemaitre RN, Kristiansson K, Nuotio ML, Houston DK, Perala MM, Qi QB, Sonestedt E, Manichaikul A, Kanoni S, Ganna A, Mikkila V, North KE, Siscovick DS, Harald K, Mckeown NM, Johansson I, Rissanen H, Liu YM, Lahti J, Hu FB, Bandinelli S, Rukh G, Rich S, Booij L, Dmitriou M, Ax E, Raitakari O, Mukamal K, Mannisto S, Hallmans G, Jula A, Ericson U, Jacobs DR, Van Rooij FJA, Deloukas P, Sjogren P, Kahonen M, Djousse L, Perola M, Barroso I, Hofman A, Stirrups K, Viikari J, Uitterlinden AG, Kalafati IP, Franco OH, Mozaffarian D, Salomaa V, Borecki IB, Knekt P, Kritchevsky SB, Eriksson JG, Dedoussis GV, Qi L, Ferrucci L, Orho-Melander M, Zillikens MC, Ingelsson E, Lehtimaki T, Renstrom F, Cupples LA, Loos RJF, Franks PW
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium (2015)
- Human Genetics
Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJM, Ikram MK, Hohn R, Vitart V, Hewitt AW, Oexle K, Makela KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, St Pourcain B, McMahon G, Kemp JP, Northstone K, Rahi JS, Cumberland PM, Martin NG, Sanfilippo PG, Lu Y, Wang YX, Hayward C, Polasek O, Campbell H, Bencic G, Wright AF, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip SP, Yap MKH, Ried JS, Gieger C, Murgia F, Wilson JF, Fleck B, Yazar S, Vingerling JR, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra BA, Zhou X, Teo YY, Tai ES, Vithana E, Barathi V, Zheng YF, Siantar RG, Neelam K, Shin YC, Lam J, Yonova-Doing E, Venturini C, Hosseini SM, Wong HS, Lehtimaki T, Kahonen M, Raitakari O, Timpson NJ, Evans DM, Khor CC, Aung T, Young TL, Mitchell P, Klein B, van Duijn CM, Meitinger T, Jonas JB, Baird PN, Mackey DA, Wong TY, Saw SM, Parssinen O, Stambolian D, Hammond CJ, Klaver CCW, Williams C, Paterson AD, Bailey-Wilson JE, Guggenheim JA
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Genome-wide association study of kidney function decline in individuals of European descent (2015)
- Kidney International
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(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci (2015)
- Human Molecular Genetics
Rahmioglu N, Macgregor S, Drong AW, Hedman ÅK, Harris HR, Randall JC, Prokopenko I, Nyholt DR, Morris AP, Montgomery GW, Missmer SA, Lindgren CM, Zondervan KT; The International Endogene Consortium (IEC); The GIANT Consortium
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption (2015)
- Molecular Psychiatry
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(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )