Olli Raitakari
 MD/PhD


olli.raitakari@utu.fi

+358 29 450 2304

Kiinamyllynkatu 10

Turku


ORCID-tunniste: https://orcid.org/0000-0001-9365-3702

Asiantuntijuusalueet
cardiovascular and metabolic diseases; risk factors; vascular epidemiology; genetic epidemiology; epidemiology; dietary intervention; cohort studies; follow-up studies

Biografia

EDUCATION AND DEGREES
 
2001   Docent in Clinical Physiology
1997-1999  Postdoc training, Royal Prince Alfred Hospital, Sydney, Australia
1997   Docent in Epidemiology
1996   Specialist in Clinical Physiology 
1995   Doctorate, PhD
1989   Licentiate in Medicine, MD

CURRENT POSITIONS

2017-                 Professor in Cardiovascular Medicine, Director of the Research Centre of Applied and 
                          Preventive Cardiovascular Medicine, University of Turku, Finland                         

 

PAST POSITIONS

2012-2016                          Academy Professor, University of Turku

2007-2016                          Professor in Cardiovascular Medicine (part time), University of Turku

2007-2008                          Senior Scientist Grant, Academy of Finland

2004-2016                          Chief Physician, Department of Clinical Physiology and Nuclear Medicine, Turku
                                           University Hospital (leave of absence 2012-2016)

2002-2004                          Consultant in Clinical Physiology and Nuclear Medicine, Turku University Hospital

2002 (1 mo)                        Head of Nuclear Medicine Department, Turku University Hospital

2000-2003 (3 mo)               Head of Clinical Physiology Department, Turku University Hospital

2000-2005                          Senior Fellow Post, Academy of Finland

1998-2000                          Postdoctoral Research Post, Academy of Finland

1996-1997                          Consultant in Clinical Physiology, Turku University Hospital

1991-1996                          Positions as Resident in Clinical Chemistry, Nuclear Medicine, and Clinical 
                                           Physiology, Turku University Hospital

1988-1990                          Positions as General Practioner and Resident in Internal Medicine or Surgery




Tutkimus

Evidence suggest that many non-communicable disease outcomes have roots in childhood and may even stem of adverse ancestral exposures. Improved knowledge how various ancestral and early-life exposures lead to adult disease outcomes is essential in developing better preventive practices and policies that lead to improved public health. My mission has been to contribute to this knowledge-base by working in epidemiologic cohort studies with follow-up from childhood to adulthood. I am the Principal Investigator of the Cardiovascular Risk in Young Finns Study (YFS), the largest study in Europe with a follow-up of cardiovascular risk factors from childhood to adulthood. I am also the Director of the STRIP Study, which is a leading long-term pediatric dietary intervention study testing the hypothesis that modifying the fat quality diet will have beneficial effects on cardiovascular risk early in life. During the past years, I have organized several field studies in these cohorts, and introduced novel technologies, such as imaging studies, genetic epidemiology methods and metabolomics approaches in these unique population resources. Our research has contributed to the understanding of pre-clinical development of atherosclerosis in children and young adults, including the effects of diet, life-style, metabolic risk factors, psychological traits and psychosocial factors, inflammation, hormones and genetic markers. For example, by applying non-invasive imaging methods in the Young Finns Study, we have demonstrated that exposure to adverse lipids, elevated blood pressure and obesity in childhood is related to atherosclerosis development in adulthood (JAMA 2003). Subsequent work stemmed from this initial observation has led to numerous original publications that have shown in detail how exposure to a large range of aetiogenic factors early in life contribute to the development of cardio-metabolic outcomes in adulthood. For example, by pooling international i3C Consortium data, we have demonstrated that overweight or obese children who became non-obese by adulthood had similar risks of many cardio-metabolic adult outcomes as individuals who were never obese (NEJM 2011). Thus, the results of our studies have clearly demonstrated that individual’s exposure to various stressors in early life is contributing to his/her adult phenotype and disease risk. The results have had significant impact on preventive practices. As a concrete demonstration of the international recognition and impact of my team’s work, many of our studies are widely cited in all updated paediatric guidelines on cardiovascular prevention both in Europe and in US.



Julkaisut
  
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  • IMI - Myopia Genetics Report  (2019)  
    • Investigative Ophthalmology & Visual Science
     Tedja MS, Haarman AEG, Meester-Smoor MA, Kaprio J, Mackey DA, Guggenheim JA, Hammond CJ, Verhoeven VJM, Klaver CCW, Bailey-Wilson JE, Baird PN, Veluchamy AB, Biino G, Burdon KP, Campbell H, Chen LJ, Cheng CY, Chew EY, Craig JE, Cumberland PM, Deangelis MM, Delcourt C, Ding XH, van Duijn CM, Evans DM, Fan Q, Fossarello M, Foster PJ, Gharahkhani P, Iglesias AI, Guol XB, Haller T, Han XK, Hayward C, He MG, Hewitt AW, Hoang Q, Hysi PG, Igo RP, Iyengar SK, Jonas JB, Kahonen M, Khawaja AP, Klein BE, Klein R, Lass JH, Lee K, Lehtimaki T, Lewis D, Li Q, Li SM, Lyytikainen LP, MacGregor S, Martin NG, Meguro A, Metspalu A, Middlebrooks C, Miyake M, Mizuki N, Musolf A, Nickels S, Oexle K, Pang CP, Parssinen O, Paterson AD, Pfeiffer N, Polasek O, Rahi JS, Raitakari O, Rudan I, Sahebjada S, Saw SM, Stambolian D, Simpson CL, Tai ES, Tideman JWL, Tsujikawa A, Verhoeven VJM, Vitart V, Wang NL, Wedenoja J, Wei WB, Williams C, Williams KM, Wilson JF, Wojciechowski R, Wang YX, Yamashiro K, Yam JCS, Yap MKH, Yazar S, Yip SP, Young TL, Zhou XT, Young TL, Yip SP, Zhou XT, Yazar S
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration Evidence from the EYE-RISK and European Eye Epidemiology Consortia  (2019)  
    • Ophthalmology: Journal of The American Academy of Ophthalmology
     Johanna M. Colijn, Anneke I. den Hollander, Ayse Demirkan, Audrey Cougnard-Grégoire, Timo Verzijden, Eveline Kersten, Magda A. Meester-Smoor, Benedicte M.J. Merle, Grigorios Papageorgiou, Shahzad Ahmad, Monique T. Mulder, Miguel Angelo Costa, Pascale Benlian, Geir Bertelsen, Alain M. Bron, Birte Claes, Catherine Creuzot-Garcher, Maja Gran Erke, Sascha Fauser, Paul J. Foster, Christopher J. Hammond, Hans-Werner Hense, Carel B. Hoyng, Anthony P. Khawaja, Jean-Francois Korobelnik, Stefano Piermarocchi, Tatiana Segato, Rufino Silva, Eric H. Souied, Katie M. Williams, Cornelia M. van Duijn, Cécile Delcourt, Caroline C.W. Klaver; for the European Eye Epidemiology Consortium and EYE-RISK Consortium
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • In Memoriam for Gerald Berenson  (2019)  
    • Hypertension
     Dwyer T, Viikari J, Sinaiko A, Burns T, Daniels S, Juonala M, Woo J, Urbina E, Steinberger J, Hu T, Raitakari O
    (    B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä )


  • Is It Good To Be Good? Dispositional Compassion and Health Behaviors  (2019)  
    • Annals of Behavioral Medicine
     Gluschkoff K., Pulkki-Råback L., Elovainio M., Saarinen A., Tammelin T., Hirvensalo M., Lehtimäki T., Keltikangas-Järvinen L., Raitakari O., Hintsanen M.
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition  (2019)  
    • PLoS Biology
     Kettunen J, Holmes MV, Allara E, Anufrieva O, Ohukainen P, Oliver-Williams C, Wang Q, Tillin T, Hughes AD, Kähönen M, Lehtimäki T, Viikari J, Raitakari OT, Salomaa V, Järvelin MR, Perola M, Davey Smith G, Chaturvedi N, Danesh J, Di Angelantonio E, Butterworth AS, Ala-Korpela M
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Longitudinal analysis of risk of Non-Alcoholic Fatty Liver Disease (NAFLD) in adulthood  (2019)  
    • Liver International
     Cuthbertson Daniel J., Brown Emily, Koskinen Juha, Magnussen Costan G., Hutri-Kähönen Nina, Sabin Matthew, Tossavainen Päivi, Jokinen Eero, Laitinen Tomi, Viikari Jorma, Raitakari Olli T., Juonala Markus
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Longitudinal effect of 20-year infancy-onset dietary intervention on food consumption and nutrient intake: the randomized controlled STRIP study  (2019)  
    • European Journal of Clinical Nutrition
     Laurie A. Matthews, Suvi P. Rovio, Johanna M Jaakkola, Harri Niinikoski, Hanna Lagström, Antti Jula, Jorma S. A. Viikari, Tapani Rönnemaa, Olli Simell, Olli T. Raitakari, Katja Pahkala
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative surveys  (2019)  
    • Lancet
     Zhou B, Danaei G, Stevens GA, Bixby H, Taddei C, Carrillo-Larco RM, Solomon B, Riley LM, Di Cesare M, Iurilli MLC, Rodriguez-Martinez A, Zhu A, Hajifathalian K, Amuzu A, Banegas JR, Bennett JE, Cameron C, Cho Y, Clarke J, Craig CL, Cruz JJ, Gates L, Giampaoli S, Gregg EW, Hardy R, Hayes AJ, Ikeda N, Jackson RT, Jennings G, Joffres M, Khang YH, Koskinen S, Kuh D, Kujala UM, Laatikainen T, Lehtimaki T, Lopez-Garcia E, Lundqvist A, Maggi S, Magliano DJ, Mann JI, McLean RM, McLean SB, Miller JC, Morgan K, Neuhauser HK, Niiranen TJ, Noale M, Oh K, Palmieri L, Panza F, Parnell WR, Peltonen M, Raitakari O, Rodriguez-Artalejo F, Roy JGR, Salomaa V, Sarganas G, Servais J, Shaw JE, Shibuya K, Solfrizzi V, Stavreski B, Tan EJ, Turley ML, Vanuzzo D, Viikari-Juntura E, Weerasekera D, Ezzati M, Weerasekera D, Ezzati M
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Long-Term Burden of Increased Body Mass Index from Childhood on Adult Dyslipidemia: The i3C Consortium Study  (2019)  
    • Journal of Clinical Medicine
     Yan Y, Bazzano LA, Juonala M, Raitakari OT, Viikari JSA, Prineas R, Dwyer T, Sinaiko A, Burns TL, Daniels SR, Woo JG, Khoury PR, Urbina EM, Jacobs DR Jr, Hu T, Steinberger J, Venn A, Chen W
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents  (2019)  
    • Acta Paediatrica
     Sergey Sadov, Helena E. Virtanen, Katharina M. Main, Anna‐Maria Andersson, Anders Juul, Antti Jula, Olli T. Raitakari, Katja Pahkala, Harri Niinikoski, Jorma Toppari
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors  (2019)  
    • Nature Genetics
     Warrington N.M., Beaumont R.N., Horikoshi M., Day F.R., Helgeland Ø., Laurin C., Bacelis J., Peng S., Hao K., Feenstra B., Wood A.R., Mahajan A., Tyrrell J., Robertson N.R., Rayner N.W., Qiao Z., Moen G.-H., Vaudel M., Marsit C.J., Chen J., Nodzenski M., Schnurr T.M., Zafarmand M.H., Bradfield J.P., Grarup N., Kooijman M.N., Li-Gao R., Geller F., Ahluwalia T.S., Paternoster L., Rueedi R., Huikari V., Hottenga J.-J., Lyytikäinen L.-P., Cavadino A., Metrustry S., Cousminer D.L., Wu Y., Thiering E., Wang C.A., Have C.T., Vilor-Tejedor N., Joshi P.K., Painter J.N., Ntalla I., Myhre R., Pitkänen N., van Leeuwen E.M., Joro R., Lagou V., Richmond R.C., Espinosa A., Barton S.J., Inskip H.M., Holloway J.W., Santa-Marina L., Estivill X., Ang W., Marsh J.A., Reichetzeder C., Marullo L., Hocher B., Lunetta K.L., Murabito J.M., Relton C.L., Kogevinas M., Chatzi L., Allard C., Bouchard L., Hivert M.-F., Zhang G., Muglia L.J., Heikkinen J., Morgen C.S., van Kampen A.H.C., van Schaik B.D.C., Mentch F.D., Langenberg C., Luan J., Scott R.A., Zhao J.H., Hemani G., Ring S.M., Bennett A.J., Gaulton K.J., Fernandez-Tajes J., van Zuydam N.R., Medina-Gomez C., de Haan H.G., Rosendaal F.R., Kutalik Z., Marques-Vidal P., Das S., Willemsen G., Mbarek H., Müller-Nurasyid M., Standl M., Appel E.V.R., Fonvig C.E., Trier C., van Beijsterveldt C.E.M., Murcia M., Bustamante M., Bonas-Guarch S., Hougaard D.M., Mercader J.M., Linneberg A., Schraut K.E., Lind P.A., Medland S.E., Shields B.M., Knight B.A., Chai J.-F., Panoutsopoulou K., Bartels M., Sánchez F., Stokholm J., Torrents D., Vinding R.K., Willems S.M., Atalay M., Chawes B.L., Kovacs P., Prokopenko I., Tuke M.A., Yaghootkar H., Ruth K.S., Jones S.E., Loh P.-R., Murray A., Weedon M.N., Tönjes A., Stumvoll M., Michaelsen K.F., Eloranta A.-M., Lakka T.A., van Duijn C.M., Kiess W., Körner A., Niinikoski H., Pahkala K., Raitakari O.T., Jacobsson B., Zeggini E., Dedoussis G.V., Teo Y.-Y., Saw S.-M., Montgomery G.W., Campbell H., Wilson J.F., Vrijkotte T.G.M., Vrijheid M., de Geus E.J.C.N., Hayes M.G., Kadarmideen H.N., Holm J.-C., Beilin L.J., Pennell C.E., Heinrich J., Adair L.S., Borja J.B., Mohlke K.L., Eriksson J.G., Widén E.E., Hattersley A.T., Spector T.D., Kähönen M., Viikari J.S., Lehtimäki T., Boomsma D.I., Sebert S., Vollenweider P., Sørensen T.I.A., Bisgaard H., Bønnelykke K., Murray J.C., Melbye M., Nohr E.A., Mook-Kanamori D.O., Rivadeneira F., Hofman A., Felix J.F., Jaddoe V.W.V., Hansen T., Pisinger C., Vaag A.A., Pedersen O., Uitterlinden A.G., Järvelin M.-R., Power C., Hyppönen E., Scholtens D.M., Lowe W.L., Jr, Davey Smith G., Timpson N.J., Morris A.P., Wareham N.J., Hakonarson H., Grant S.F.A., Frayling T.M., Lawlor D.A., Njølstad P.R., Johansson S., Ong K.K., McCarthy M.I., Perry J.R.B., Evans D.M., Freathy R.M.; EGG Consortium
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits  (2019)  
    • Nature Communications
     Eleonora Porcu, Sina Rüeger, Kaido Lepik; eQTLGen Consortium; BIOS Consortium; Federico A. Santoni, Alexandre Reymond, Zoltán Kutalik
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Migraine polygenic risk score associates with efficacy of migraine-specific drugs  (2019)  
    • Neurology-Genetics
     Kogelman LJA, Esserlind AL, Christensen AF, Awasthi S, Ripke S, Ingason A, Davidsson OB, Erikstrup C, Hjalgrim H, Ullum H, Olesen J, Hansen TF, Gudbjartsson D, Gastafsson O, Stefansson K, Stefansson H, Porsteinsdottir U, Andersen S, Banasik K, Brunak S, Buil A, Burgdorf K, Gregor J, Jennum P, Nielsen KR, Nyegaard M, Paarup HM, Pedersen OB, Sorensen E, Werge T, Anttila V, Artto V, Belin AC, de Boer I, Boomsma DI, Borte S, Chasman DI, Cherkas L, Cormand B, Cuenca-Leon E, Davey-Smith G, Dichgans M, van Duijn C, Esko T, Ferrari M, Frants RR, Freilinger T, Furlotte N, Gormley P, Griffiths L, Hamalainen E, Hiekkala M, Ikram MA, Jarvelin MR, Kajanne R, Kallela M, Kaprio J, Kaunisto M, Kubisch C, Kurki M, Kurth T, Launer L, Lehtimaki T, Lessel D, Ligthart L, Litterman N, van den Maagdenberg A, Macaya A, Malik R, Mangino M, McMahon G, Muller-Myhsok B, Neale BM, Northover C, Nyholt DR, Palotie A, Palta P, Pedersen L, Pedersen N, Posthuma D, Pozo-Rosich P, Pressman A, Raitakari O, Schurks M, Sintas C, Steinberg S, Strachan D, Terwindt G, Vila-Pueyo M, Wessman M, Winsvold BS, Zhao HY, Zwart JA, Zwart JA, Zhao HY, Winsvold BS
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions  (2019)  
    • American Journal of Epidemiology
     de Vries P.S., Brown M.R., Bentley A.R., Sung Y.J., Winkler T.W., Ntalla I., Schwander K., Kraja A.T., Guo X., Franceschini N., Cheng C.-Y., Sim X., Vojinovic D., Huffman J.E., Musani S.K., Li C., Feitosa M.F., Richard M.A., Noordam R., Aschard H., Bartz T.M., Bielak L.F., Deng X., Dorajoo R., Lohman K.K., Manning A.K., Rankinen T., Smith A.V., Tajuddin S.M., Evangelou E., Graff M., Alver M., Boissel M., Chai J.F., Chen X., Divers J., Gandin I., Gao C., Goel A., Hagemeijer Y., Harris S.E., Hartwig F.P., He M., Horimoto A.R.V.R., Hsu F.-C., Jackson A.U., Kasturiratne A., Komulainen P., Kühnel B., Laguzzi F., Lee J.H., Luan J., Lyytikäinen L.-P., Matoba N., Nolte I.M., Pietzner M., Riaz M., Said M.A., Scott R.A., Sofer T., Stančáková A., Takeuchi F., Tayo B.O., van der Most P.J., Varga T.V., Wang Y., Ware E.B., Wen W., Yanek L.R., Zhang W., Zhao J.H., Afaq S., Amin N., Amini M., Arking D.E., Aung T., Ballantyne C., Boerwinkle E., Broeckel U., Campbell A., Canouil M., Charumathi S., Chen Y.-D.I., Connell J.M., de Faire U., de Las Fuentes L., de Mutsert R., de Silva H.J., Ding J., Dominiczak A.F., Duan Q., Eaton C.B., Eppinga R.N., Faul J.D., Fisher V., Forrester T., Franco O.H., Friedlander Y., Ghanbari M., Giulianini F., Grabe H.J., Grove M.L., Gu C.C., Harris T.B., Heikkinen S., Heng C.-K., Hirata M., Hixson J.E., Howard B.V., Ikram M.A., InterAct Consortium, Jacobs D.R., Johnson C., Jonas J.B., Kammerer C.M., Katsuya T., Khor C.C., Kilpeläinen T.O., Koh W.-P., Koistinen H.A., Kolcic I., Kooperberg C., Krieger J.E., Kritchevsky S.B., Kubo M., Kuusisto J., Lakka T.A., Langefeld C.D., Langenberg C., Launer L.J., Lehne B., Lemaitre R.N., Li Y., Liang J., Liu J., Liu K., Loh M., Louie T., Mägi R., Manichaikul A.W., McKenzie C.A., Meitinger T., Metspalu A., Milaneschi Y., Milani L., Mohlke K.L., Mosley T.H., Mukamal K.J., Nalls M.A., Nauck M., Nelson C.P., Sotoodehnia N., O'Connell J.R., Palmer N.D., Pazoki R., Pedersen N.L., Peters A., Peyser P.A., Polasek O., Poulter N., Raffel L.J., Raitakari O.T., Reiner A.P., Rice T.K., Rich S.S., Robino A., Robinson J.G., Rose L.M., Rudan I., Schmidt C.O., Schreiner P.J., Scott W.R., Sever P., Shi Y., Sidney S., Sims M., Smith B.H., Smith J.A., Snieder H., Starr J.M., Strauch K., Tan N., Taylor K.D., Teo Y.Y., Tham Y.C., Uitterlinden A.G., van Heemst D., Vuckovic D., Waldenberger M., Wang L., Wang Y., Wang Z., Wei W.B., Williams C., Wilson G., Wojczynski M.K., Yao J., Yu B., Yu C., Yuan J.-M., Zhao W., Zonderman A.B., Becker D.M., Boehnke M., Bowden D.W., Chambers J.C., Deary I.J., Esko T., Farrall M., Franks P.W., Freedman B.I., Froguel P., Gasparini P., Gieger C., Horta B.L., Kamatani Y., Kato N., Kooner J.S., Laakso M., Leander K., Lehtimäki T., Lifelines Cohort, Groningen, The Netherlands (Lifelines Cohort Study), Magnusson P.K.E., Penninx B., Pereira A.C., Rauramaa R., Samani N.J., Scott J., Shu X.-O., van der Harst P., Wagenknecht L.E., Wang Y.X., Wareham N.J., Watkins H., Weir D.R., Wickremasinghe A.R., Zheng W., Elliott P., North K.E., Bouchard C., Evans M.K., Gudnason V., Liu C.-T., Liu Y., Psaty B.M., Ridker P.M., van Dam R.M., Kardia S.L.R., Zhu X., Rotimi C.N., Mook-Kanamori D.O., Fornage M., Kelly T.N., Fox E.R., Hayward C., van Duijn C.M., Tai E.S., Wong T.Y., Liu J., Rotter J.I., Gauderman W.J., Province M.A., Munroe P.B., Rice K., Chasman D.I., Cupples L.A., Rao D.C., Morrison A.C.
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids  (2019)  
    • Nature Genetics
     Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo XQ, Liu JM, Lu YC, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li CW, Feitosa MF, Richard MA, Noordam R, Baker J, Chen GJ, Aschard H, Bartz TM, Ding JZ, Dorajoo R, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Zhao W, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He MA, Horimoto ARVR, Hsu FC, Hung YJ, Jackson AU, Kasturiratne A, Komulainen P, Kuhnel B, Leander K, Lin KH, Luan JA, Lyytikainen LP, Matoba N, Nolte IM, Pietzner M, Prins B, Riaz M, Robino A, Said MA, Schupf N, Scott RA, Sofer T, Stancakova A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang TD, Wang YJ, Ware EB, Wen WQ, Xiang YB, Yanek LR, Zhang WH, Zhao JH, Adeyemo A, Afaq S, Amin N, Amini M, Arking DE, Arzumanyan Z, Aung T, Ballantyne C, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Broeckel U, Brown M, Cade BE, Campbell A, Canouil M, Charumathi S, Chen YDI, Christensen K, Concas MP, Connell JM, de las Fuentes L, de Silva HJ, de Vries PS, Doumatey A, Duan Q, Eaton CB, Eppinga RN, Faul JD, Floyd JS, Forouhi NG, Forrester T, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gharib SA, Gigante B, Giulianini F, Grabe HJ, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Ikram MA, Jia YC, Joehanes R, Johnson C, Jonas JB, Justice AE, Katsuya T, Khor CC, Kilpelainen TO, Koh WP, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li YZ, Liang JJ, Lin S, Liu CT, Liu JJ, Liu K, Loh M, Lohman KK, Louie T, Luzzi A, Magi R, Mahajan A, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Morris AP, Murray AD, Nalls MA, Nauck M, Nelson CP, North KE, O'Connell JR, Palmer ND, Papanicolau GJ, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raitakari OT, Reiner AP, Renstrom F, Rice TK, Rich SS, Robinson JG, Rose LM, Rosendaal FR, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Tiemeier H, Turner ST, Uitterlinden AG, van Heemst D, Waldenberger M, Wang HM, Wang L, Wang LH, Wei WB, Williams CA, Wilson G, Wojczynski MK, Yao J, Young K, Yu CZ, Yuan JM, Zhou J, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Cooper RS, de Faire U, Deary IJ, Elliott P, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Juang JMJ, Kamatani Y, Kammerer CM, Kato N, Kooner JS, Laakso M, Laurie CC, Lee IT, Lehtimaki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Pereira AC, Rauramaa R, Redline S, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang JS, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu TC, Zeggini E, Zheng W, Bouchard C, Evans MK, Gudnason V, Kardia SLR, Liu YM, Psaty BM, Ridker PM, van Dam RM, Mook-Kanamori DO, Fornage M, Province MA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Franceschini N, Rotter JI, Zhu XF, Bierut LJ, Gauderman WJ, Rice K, Munroe PB, Morrison AC, Rao DC, Rotimi CN, Cupples LA
    (    A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )


  • Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration  (2019)  
    • Nature Communications
     Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ, Schwander K, Cade BE, Manning A, Aschard H, Brown MR, Chen H, Franceschini N, Musani SK, Richard M, Vojinovic D, Aslibekyan S, Bartz TM, de Las Fuentes L, Feitosa M, Horimoto AR, Ilkov M, Kho M, Kraja A, Li C, Lim E, Liu Y, Mook-Kanamori DO, Rankinen T, Tajuddin SM, van der Spek A, Wang Z, Marten J, Laville V, Alver M, Evangelou E, Graff ME, He M, Kühnel B, Lyytikäinen LP, Marques-Vidal P, Nolte IM, Palmer ND, Rauramaa R, Shu XO, Snieder H, Weiss S, Wen W, Yanek LR, Adolfo C, Ballantyne C, Bielak L, Biermasz NR, Boerwinkle E, Dimou N, Eiriksdottir G, Gao C, Gharib SA, Gottlieb DJ, Haba-Rubio J, Harris TB, Heikkinen S, Heinzer R, Hixson JE, Homuth G, Ikram MA, Komulainen P, Krieger JE, Lee J, Liu J, Lohman KK, Luik AI, Mägi R, Martin LW, Meitinger T, Metspalu A, Milaneschi Y, Nalls MA, O'Connell J, Peters A, Peyser P, Raitakari OT, Reiner AP, Rensen PCN, Rice TK, Rich SS, Roenneberg T, Rotter JI, Schreiner PJ, Shikany J, Sidney SS, Sims M, Sitlani CM, Sofer T, Strauch K, Swertz MA, Taylor KD, Uitterlinden AG, van Duijn CM, Völzke H, Waldenberger M, Wallance RB, van Dijk KW, Yu C, Zonderman AB, Becker DM, Elliott P, Esko T, Gieger C, Grabe HJ, Lakka TA, Lehtimäki T, North KE, Penninx BWJH, Vollenweider P, Wagenknecht LE, Wu T, Xiang YB, Zheng W, Arnett DK, Bouchard C, Evans MK, Gudnason V, Kardia S, Kelly TN, Kritchevsky SB, Loos RJF, Pereira AC, Province M, Psaty BM, Rotimi C, Zhu X, Amin N, Cupples LA, Fornage M, Fox EF, Guo X, Gauderman WJ, Rice K, Kooperberg C, Munroe PB, Liu CT, Morrison AC, Rao DC, van Heemst D, Redline S
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  • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity  (2019)  
    • Nature Communications
     Kilpeläinen T.O., Bentley A.R., Noordam R., Sung Y.J., Schwander K., Winkler T.W., Jakupović H., Chasman D.I., Manning A., Ntalla I., Aschard H., Brown M.R., de las Fuentes L., Franceschini N., Guo X., Vojinovic D., Aslibekyan S., Feitosa M.F., Kho M., Musani S.K., Richard M., Wang H., Wang Z., Bartz T.M., Bielak L.F., Campbell A., Dorajoo R., Fisher V., Hartwig F.P., Horimoto A.R.V.R., Li C., Lohman K.K., Marten J., Sim X., Smith A.V., Tajuddin S.M., Alver M., Amini M., Boissel M., Chai J.F., Chen X., Divers J., Evangelou E., Gao C., Graff M., Harris S.E., He M., Hsu F.-C., Jackson A.U., Zhao J.H., Kraja A.T., Kühnel B., Laguzzi F., Lyytikäinen L.-P., Nolte I.M., Rauramaa R., Riaz M., Robino A., Rueedi R., Stringham H.M., Takeuchi F., van der Most P.J., Varga T.V., Verweij N., Ware E.B., Wen W., Li X., Yanek L.R., Amin N., Arnett D.K., Boerwinkle E., Brumat M., Cade B., Canouil M., Chen Y.-D.I., Concas M.P., Connell J., de Mutsert R., de Silva H.J., de Vries P.S., Demirkan A., Ding J., Eaton C.B., Faul J.D., Friedlander Y., Gabriel K.P., Ghanbari M., Giulianini F., Gu C.C., Gu D., Harris T.B., He J., Heikkinen S., Heng C.-K., Hunt S.C., Ikram M.A., Jonas J.B., Koh W.-P., Komulainen P., Krieger J.E., Kritchevsky S.B., Kutalik Z., Kuusisto J., Langefeld C.D., Langenberg C., Launer L.J., Leander K., Lemaitre R.N., Lewis C.E., Liang J., Alizadeh B.Z., Boezen H.M., Franke L., Navis G., Rots M., Swertz M., Wolffenbuttel B.H.R., Wijmenga C., Liu J., Mägi R., Manichaikul A., Meitinger T., Metspalu A., Milaneschi Y., Mohlke K.L., Mosley T.H., Jr., Murray A.D., Nalls M.A., Nang E.-E.K., Nelson C.P., Nona S., Norris J.M., Nwuba C.V., O’Connell J., Palmer N.D., Papanicolau G.J., Pazoki R., Pedersen N.L., Peters A., Peyser P.A., Polasek O., Porteous D.J., Poveda A., Raitakari O.T., Rich S.S., Risch N., Robinson J.G., Rose L.M., Rudan I., Schreiner P.J., Scott R.A., Sidney S.S., Sims M., Smith J.A., Snieder H., Sofer T., Starr J.M., Sternfeld B., Strauch K., Tang H., Taylor K.D., Tsai M.Y., Tuomilehto J., Uitterlinden A.G., van der Ende M.Y., van Heemst D., Voortman T., Waldenberger M., Wennberg P., Wilson G., Xiang Y.-B., Yao J., Yu C., Yuan J.-M., Zhao W., Zonderman A.B., Becker D.M., Boehnke M., Bowden D.W., de Faire U., Deary I.J., Elliott P., Esko T., Freedman B.I., Froguel P., Gasparini P., Gieger C., Kato N., Laakso M., Lakka T.A., Lehtimäki T., Magnusson P.K.E., Oldehinkel A.J., Penninx B.W.J.H., Samani N.J., Shu X.-O., van der Harst P., Van Vliet-Ostaptchouk J.V., Vollenweider P., Wagenknecht L.E., Wang Y.X., Wareham N.J., Weir D.R., Wu T., Zheng W., Zhu X., Evans M.K., Franks P.W., Gudnason V., Hayward C., Horta B.L., Kelly T.N., Liu Y., North K.E., Pereira A.C., Ridker P.M., Tai E.S., van Dam R.M., Fox E.R., Kardia S.L.R., Liu C.-T., Mook-Kanamori D.O., Province M.A., Redline S., van Duijn C.M., Rotter J.I., Kooperberg C.B., Gauderman W.J., Psaty B.M., Rice K., Munroe P.B., Fornage M., Cupples L.A., Rotimi C.N., Morrison A.C., Rao D.C., Loos R.J.F.; Lifelines Cohort Study
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  • Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy  (2019)  
    • American Journal of Human Genetics
     Nath AP, Ritchie SC, Grinberg NF, Tang HH, Huang QQ, Teo SM, Ahola-Olli AV, Würtz P, Havulinna AS, Santalahti K, Pitkänen N, Lehtimäki T, Kähönen M, Lyytikäinen LP, Raitoharju E, Seppälä I, Sarin AP, Ripatti S, Palotie A, Perola M, Viikari JS, Jalkanen S, Maksimow M, Salmi M, Wallace C, Raitakari OT, Salomaa V, Abraham G, Kettunen J, Inouye M
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  • Natural History of Atherosclerosis and Abdominal Aortic Intima-Media Thickness: Rationale, Evidence, and Best Practice for Detection of Atherosclerosis in the Young  (2019)  
    • Journal of Clinical Medicine
     Michael R. Skilton, David S. Celermajer, Erich Cosmi, Fatima Crispi, Samuel S. Gidding, Olli T. Raitakari, Elaine M. Urbina
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  • New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders  (2019)  
    • Nature Human Behaviour
     Evangelos Evangelou, He Gao, Congying Chu, Georgios Ntritsos, Paul Blakeley, Andrew R. Butts, Raha Pazoki, Hideaki Suzuki, Fotios Koskeridis, Andrianos M. Yiorkas, Ibrahim Karaman, Joshua Elliott, Qiang Luo, Stefanie Aeschbacher, Traci M. Bartz, Sebastian E. Baumeister, Peter S. Braund, Michael R. Brown, Jennifer A. Brody, Toni-Kim Clarke, Niki Dimou, Jessica D. Faul, Georg Homuth, Anne U. Jackson, Katherine A. Kentistou, Peter K. Joshi, Rozenn N. Lemaitre, Penelope A. Lind, Leo-Pekka Lyytikäinen, Massimo Mangino, Yuri Milaneschi, Christopher P. Nelson, Ilja M. Nolte, Mia-Maria Perälä, Ozren Polasek, David Porteous, Scott M. Ratliff, Jennifer A. Smith, Alena Stančáková, Alexander Teumer, Samuli Tuominen, Sébastien Thériault, Jagadish Vangipurapu, John B. Whitfield, Alexis Wood, Jie Yao, Bing Yu, Wei Zhao, Dan E. Arking, Juha Auvinen, Chunyu Liu, Minna Männikkö, Lorenz Risch, Jerome I. Rotter, Harold Snieder, Juha Veijola, Alexandra I. Blakemore, Michael Boehnke, Harry Campbell, David Conen, Johan G. Eriksson, Hans J. Grabe, Xiuqing Guo, Pim van der Harst, Catharina A. Hartman, Caroline Hayward, Andrew C. Heath, Marjo-Riitta Jarvelin, Mika Kähönen, Sharon L. R. Kardia, Michael Kühne, Johanna Kuusisto, Markku Laakso, Jari Lahti, Terho Lehtimäki, Andrew M. McIntosh, Karen L. Mohlke, Alanna C. Morrison, Nicholas G. Martin, Albertine J. Oldehinkel, Brenda W. J. H. Penninx, Bruce M. Psaty, Olli T. Raitakari, Igor Rudan, Nilesh J. Samani, Laura J. Scott, Tim D. Spector, Niek Verweij, David R. Weir, James F. Wilson, Daniel Levy, Ioanna Tzoulaki, Jimmy D. Bell, Paul M. Matthews, Adrian Rothenfluh, Sylvane Desrivières, Gunter Schumann, Paul Elliott
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Last updated on 2023-12-07 at 12:01