Petri Susi
PhD, docent in molecular virology (University of Turku)
pesusi@utu.fi +358 29 450 4556 +358 46 922 7336 Kiinamyllynkatu 10 Turku Työhuone: D7062 ORCID-tunniste: https://orcid.org/0000-0002-9245-3271 |
Picornavirus; enterovirus; rhinovirus; parechovirus; virus evolution; bioinformatics; respiratory pathogens; clinical virology; diagnostics; protein production technologies; bioprocesses; cell culture techniques; molecular biology; gene technology; biosecurity; research data management;
I studied biochemistry and plant biology as major subjects at University of Turku (Turku, Finland) and graduated with MSc degree in biology in 1994. The following five years (1995-1999) I worked as doctoral student at University of Helsinki (Helsinki, Finland) with prof. Eija Pehu and Dr. Kirsi Lehto, and visited Agrotechnological Research Institute (Wageningen, Netherlands; with Dr. Chris van der Schoot) and The James Hutton Institute (Dundee, UK; with Dr. Lesley Torrance) to learn new techniques. I obtained my PhD degree in the field of plant virology in 1999. As a post-doc, I first did a short visit to cancer cell biology in Turku Bioscience (in 2000; with Dr. Päivi Koskinen), before a four-year period as Academy of Finland post-doctoral researcher. During those years, I worked with FLP/FRT gene editing system in plants with a twist to plant virus movement processes in Joint Biotechnology Laboratory at University of Turku. Following that period, I switched from plant virology to human picornavirus research, and joined the group of prof. Timo Hyypiä. This started by career as a university staff member in Institute of Biomedicine (Faculty of Medicine, University of Turku). Currently, I am in a position of university lecturer in medical biotechnology and microbiology. My work history also includes research visits to diagnostic companies in Finland (2015 and 2017) and abroad (2015), two years as project manager at Turku University of Applied Sciences (2012-2013), and expert work in Tykslab clinical virology unit (2006-2012). I have co-founded two start-up companies.
I am interested in the relationship between picornavirus genome evolution, cellular infectivity and disease mechanisms, which are the key elements in therapy development. My current projects include NGS sequencing of human picornaviruses, receptor research on entero- and parechoviruses, and development of novel diagnostics to picornaviruses and novel enterovirus vectors for cancer therapy.
- Obatoclax inhibits alphavirus membrane fusion by neutralizing the acidic environment of endocytic compartments (2017)
- Antimicrobial Agents and Chemotherapy
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test (2016)
- New Microbes and New Infections
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Human Parechovirus 1 Infection Occurs via alpha V beta 1 Integrin (2016)
- PLoS ONE
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Integrins are not essential for entry of coxsackievirus A9 into SW480 human colon adenocarcinoma cells (2016)
- Virology Journal
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Role of Heparan Sulfate in Cellular Infection of Integrin-Binding Coxsackievirus A9 and Human Parechovirus 1 Isolates (2016)
- PLoS ONE
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Therapeutic Use of Native and Recombinant Enteroviruses (2016)
- Viruses
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Amino-terminus of oleosin protein defines the size of oil bodies - Topological model of oleosin-oil body complex (2015)
- Journal of Plant Biochemistry and Physiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Diagnostiikka ja teollinen mikrobiologia –tutkimusryhmän fokus (2015) Innostavia työelämän kehittämisratkaisuja Susi P
(D2 Artikkeli ammatillisessa kokoomateoksessa) - Differential effects of viral coat protein on induction of hypersensitive response and systemic movement of Tobacco mosaic virus and Tobacco mild green mosaic virus in Nicotiana megalosiphon. (2015)
- Journal of Plant Pathology & Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Elicitation of T-cell responses by structural and non-structural proteins of coxsackievirus B4 (2015)
- Journal of General Virology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Generation and characterization of a single-chain anti-EphA2 antibody (2014)
- Growth Factors
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Genome Sequence of Coxsackievirus A6, Isolated during a Hand-Foot-and-Mouth Disease Outbreak in Finland in 2008. (2014) Österback R, Koskinen S, Merilahti P, Pursiheimo JP, Blomqvist S, Roivainen M, Laiho A, Susi P, Waris M
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Isolation and identification of cyclic lipopeptides from Paenibacillus ehimensis, strain IB-X-b (2014)
- Journal of Chromatography B
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Complete genome sequences of three strains of coxsackievirus A7 (2013) Ylä-Pelto J, Koskinen S, Karelehto E, Sittig E, Roivainen M, Hyypiä T, Susi P
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - High-level expression of a full-length Eph receptor (2013)
- Protein Expression and Purification
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Simultaneous Detection and Differentiation of Human Rhino- and Enteroviruses in Clinical Specimens by Real-Time PCR with Locked Nucleic Acid Probes (2013)
- Journal of Clinical Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Status and prospects of plant virus control through interference with vector transmission (2013)
- Annual Review of Phytopathology
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Structural and functional analysis of coxsackievirus A9 integrin αVβ6 binding and uncoating (2013)
- Journal of Virology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Endocytosis of integrin-binding human picornaviruses (2012)
- Advances in Virology
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Structural analysis of coxsackievirus A7 reveals conformational changes associated with uncoating (2012)
- Journal of Virology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )