Terho Heikkinen
 Professor of Paediatrics, MD, PhD


teheikki@utu.fi




ORCID identifierhttps://orcid.org/0000-0001-6504-0116





Areas of expertise
Paediatric infectious diseases; respiratory infections; respiratory viruses; vaccinations; influenza; respiratory syncytial virus; otitis media

Research community or research topic
Respiratory infections in children; RESCEU (EU/IMI-funded project 2017-2021); INFORM study

Biography



Professor Terho Heikkinen graduated from the Medical School at the
University of Turku in 1984, where he also specialized in Paediatrics and Paediatric
Infectious Diseases. He defended his thesis on Development and prevention of acute
otitis media in children in 1994. Having received the European Society for
Paediatric Infectious Diseases Fellowship Award, he worked in 1996-1998 as
a post-doc Research Fellow at the University of Texas Medical Branch at
Galveston, USA. Subsequently, he worked as a Senior Clinical Researcher and
Clinical Lecturer at the Department of Paediatrics, University of Turku. Since
2016, he has been Professor of Paediatrics at
the Faculty of Medicine, University of Turku.

During the years, Terho Heikkinen has served as the chairman or a board member
of several international and domestic societies in the field of paediatric
infectious diseases, including the President of the World Society for
Pediatric Infectious Diseases. He is currently a board member of the European Scientific
Working Group on Influenza (ESWI), a scientific advisory board and executive committee member of the global Respiratory Syncytial Virus Network (ReSViNET), and the chairman of the Nordic Research Network for Paediatric Infectious Diseases (NORDPID).



Research



Terho Heikkinen´s major research interest lies in respiratory infections,
especially those caused by influenza or respiratory syncytial viruses. In year 2000, he founded his own research group and initiated a long-term research project on respiratory virus infections in children,
including the etiology, epidemiology, diagnosis, treatment, prevention, and
overall societal impact of these infections and their complications.

Terho Heikkinen has been
actively involved in international research collaboration. In 2014, he was a founding member of ReSViNET, a global respiratory syncytial virus research network.
He is also a principal investigator in RESCEU (Respiratory syncytial virus
consortium in Europe) that in 2017 received 5-year EU/IMI funding for research
on the burden of respiratory syncytial virus infections in Europe. He was also a founding member of the Nordic Research Network for Paediatric Infectious Diseases (NORDPID) that was established in 2018.



 



Teaching

Since 1999, Terho Heikkinen has worked as a full-time
teacher of paediatrics at the Department of Paediatrics, University of Turku. He
is also responsible for the organization of the biannual International Course
of Paediatrics & Adolescent Medicine for international Erasmus students. He
has given 188 invited lectures at various international and domestic academic
meetings.






Publications
  
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  • The genomic evolutionary dynamics and global circulation patterns of respiratory syncytial virusRespiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape  (2024)  
    • Nature CommunicationsLancet Infectious Diseases
     Langedijk Annefleur C., Vrancken Bram, Lebbink Robert Jan, Wilkins Deidre, Kelly Elizabeth J., Baraldi Eugenio, Mascareñas de Los Santos Abiel Homero, Danilenko Daria M., Choi Eun Hwa, Palomino María Angélica, Chi Hsin, Keller Christian, Cohen Robert, Papenburg Jesse, Pernica Jeffrey, Greenough Anne, Richmond Peter, Martinón-Torres Federico, Heikkinen Terho, Stein Renato T., Hosoya Mitsuaki, Nunes Marta C., Verwey Charl, Evers Anouk, Kragten-Tabatabaie Leyla, Suchard Marc A., Kosakovsky Pond Sergei L., Poletto Chiara, Colizza Vittoria, Lemey Philippe, Bont Louis J., Priante Elena, Komissarova Kseniya, Yun Ki Wook, Clement Pascale, Bauck Monica, Gupta Atul, Wadia Ushma, Rivero-Calle Irene, Lumertz Magalia, Hasimoto Koichi, Madhi Shabir A.; on behalf of the INFORM-RSV Study Group
    (
    A1 Refereed original research article in a scientific journal)


  • The respiratory microbiome is linked to the severity of RSV infections and the persistence of symptoms in childrenThe burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study  (2024)  
    • Cell Reports Medicine
     Kristensen, Maartje; de Steenhuijsen, Piters Wouter A.A.; Wildenbeest, Joanne; van Houten, Marlies A.; Zuurbier, Roy P.; Hasrat, Raiza; Arp, Kayleigh; Chu, Mei Ling J.N.; Billard, Marie; Heikkinen, Terho; Cunningham, Steve; Snape, Matthew; Drysdale, Simon B.; Thwaites, Ryan S.; Martinon-Torres, Federico; Pollard, Andrew J.; Openshaw, Peter J.M.; Aerssen, Jeroen; Binkowska, Justyna; Bont, Louis; Bogaert, Debby; REspiratory Syncytial virus Consortium in EUrope (RESCEU) investigators
    (
    A1 Refereed original research article in a scientific journal)


  • Uudet keinot käyttöön RSV:n ehkäisyssä  (2024)  
    • Duodecim
     Heinonen, Santtu; Heikkinen, Terho
    (
    D1 Article in a professional journal)


  • Burden of Respiratory Syncytial Virus in the European Union: estimation of RSV-associated hospitalizations in children under 5 years  (2023)  
    • Journal of Infectious Diseases
     Del Riccio M, Spreeuwenberg P, Osei-Yeboah R, Johannesen CK, Fernandez LV, Teirlinck AC, Wang X, Heikkinen T, Bangert M, Caini S, Campbell H, Paget J; RESCEU investigators
    (
    A1 Refereed original research article in a scientific journal)


  • Cost-effectiveness of monoclonal antibody and maternal immunization against respiratory syncytial virus (RSV) in infants: Evaluation for six European countries  (2023)  
    • VaccineThe Lancet Respiratory Medicine
     Getaneh Abraham M, Li Xiao, Mao Zhuxin, Johannesen Caroline K, Barbieri Eelisa, van Summeren Jojanneke, Wang Xin, Tong Sabine, Baraldi Eugenio, Phijffer Emily, Rizzo Caterina, van Wijhe Maarten, Heikkinen Terho, Bont Louis, Willem Lander, Jit Mark, Beutels Philippe, Bilcke Joke; for Respiratory Syncytial Virus Consortium in Europe (RESCEU) investigators
    (
    A1 Refereed original research article in a scientific journal)


  • Economic burden and health-related quality-of-life among infants with respiratory syncytial virus infection: A multi-country prospective cohort study in Europe  (2023)  
    • Vaccine
     Mao Zhuxin, Li Xiao, Dacosta-Urbieta Ana, Billard Marie-Noëlle, Wildenbeest Joanne, Korsten Koos, Martinón-Torres Federico, Heikkinen Terho, Cunningham Steve, Snape Matthew D, Robinson Hannah, Pollard Andrew J, Postma Maarten, Dervaux Benoit, Hens Niels, Bont Louis, Bilcke Joke, Beutels Philippe, for RESCEU investigators
    (
    A1 Refereed original research article in a scientific journal)


  • Hengitystieinfektiot: influenssa  (2023)  Lastentaudit Peltola Ville, Heikkinen Terho
    (
    D2 Article in a professional compilation book)


  • Nirsevimab binding-site conservation in respiratory syncytial virus fusion glycoprotein worldwide between 1956 and 2021: an analysis of observational study sequencing data  (2023)  
    • Lancet Infectious Diseases
     Wilkins Deidre, Langedijk Annefleur C, Lebbink Robert Jan, Morehouse Christopher, Abram Michael E, Ahani Bahar, Aksyuk Anastasia A, Baraldi Eugenio, Brady Tyler, Tian Chen Albert, Chi Hsin, Choi Eun Hwa, Cohen Robert, Danilenko Daria M, Gopalakrishnan Vancheswaran, Greenough Anne, Heikkinen Terho, Hosoya Mitsuaki, Keller Christian, Kelly Elizabeth J, Kragten-Tabatabaie Leyla, Martinón-Torres Federico, Homero Mascareñas de Los Santos Abiel, Nunes Marta C, Palomino María Angélica, Papenburg Jesse, Pernica Jeffrey M, Richmond Peter, Stein Renato T, Tuffy Kevin M, Verwey Charl, Esser Mark T, Tabor David E, Bont Louis J; INFORM-RSV Study Group
    (
    A1 Refereed original research article in a scientific journal)


  •   (2023)  
       Mazur Natalie I, Terstappen Jonne, Baral Ranju, Bardají Azucena, Beutels Philippe, Buchholz Ursula J, Cohen Cheryl, Crowe James E, Cutland Clare L, Eckert Linda, Feikin Daniel, Fitzpatrick Tiffany, Fong Youyi, Graham Barney S, Heikkinen Terho, Higgins Deborah, Hirve Siddhivinayak, Klugman Keith P, Kragten-Tabatabaie Leyla, Lemey Philippe, Libster Romina, Löwensteyn Yvette, Mejias Asuncion, Munoz Flor M, Munywoki Patrick K, Mwananyanda Lawrence, Nair Harish, Nunes Marta C, Ramilo Octavio, Richmond Peter, Ruckwardt Tracy J, Sande Charles, Srikantiah Padmini, Thacker Naveen, Waldstein Kody A, Weinberger Dan, Wildenbeest Joanne, Wiseman Dexter, Zar Heather J, Zambon Maria, Bont Louis
      (
      A2 Refereed review article in a scientific journal )


    •   (2023)  
         Wildenbeest Joanne G, Billard Marie-Noëlle, Zuurbier Roy P, Korsten Koos, Langedijk Annefleur C, van de Ven Peter M, Snape Matthew D, Drysdale Simon B, Pollard Andrew J, Robinson Hannah, Heikkinen Terho, Cunningham Steve, O'Neill Thomas, Rizkalla Bishoy, Dacosta-Urbieta Ana, Martinón-Torres Federico, van Houten Marlies A, Bont Louis J, RESCEU Investigators
        (
        A1 Refereed original research article in a scientific journal)



      Last updated on 12/07/2023 12:37:11 PM