PhD Markus Matilainen - UTU Research Portal

Markus Matilainen
PhD

- Senior Researcher,
Clinical Neurosciences (Department of Clinical Medicine)

Turku PET Centre

manmat@utu.fi

+358 29 450 4739

+358 50 472 8469

Itäinen Pitkäkatu 4

Turku

: https://orcid.org/0000-0002-5597-2670

Statistics; Biostatistics; Blind Source Separation

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Broad rim lesions are a new pathological and imaging biomarker for rapid disease progression in multiple sclerosis (2025)
- Nature Medicine
Klotz, Luisa; Smolders, Joost; Lehto, Jussi; Matilainen, Markus; Lütje, Lukas; Buchholz, Luzia; Albrecht, Stefanie; Walter, Carolin; Varghese, Julian; Wiendl, Heinz; Nylund, Marjo; Thomas, Christian; Gardberg, Maria; van den Bosch, Aletta M. R.; Airas, Laura; Huitinga, Inge; Kuhlmann, Tanja
Hemispheric asymmetry of [11C](R)PK11195 binding to translocator protein 18 kDa (TSPO) in normal brain (2025)
- Journal of Cerebral Blood Flow and Metabolism
Alfaifi, Bandar Q.; Tuisku, Jouni; Matilainen, Markus; Anton-Rodriguez, Jose; Lewis, Daniel; Jackson, Alan; Coope, David J.; Airas, Laura; Deakin, Bill; Herholz, Karl; Gerhard, Alexander; Hinz, Rainer
Integrating TSPO-PET imaging with metabolomics for enhanced prognostic accuracy in multiple sclerosis (2025)
- BMJ neurology open
Radford-Smith, Daniel E.; Yates, Abi G.; Kacerova, Tereza; Nylund, Marjo; Sucksdorff, Marcus; Matilainen, Markus; Willemse, Eline; Oechtering, Johanna; Maceski, Aleksandra Maleska; Leppert, David; Kuhle, Jens; Probert, Fay; Anthony, Daniel C.; Airas, Laura
Longitudinal accumulation of glial activation measured by TSPO-PET predicts later brain atrophy in multiple sclerosis (2025)
- Journal of Neuroinflammation
Nylund, Marjo; Lehto, Jussi; Matilainen, Markus; Rajander, Johan; Wahlroos, Saara; Sucksdorff, Marcus; Kuhlmann, Tanja; Airas, Laura
Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis (2025)
- Journal of Neurology, Neurosurgery and Psychiatry
Ahola, Venla; Saraste, Maija; Nylund, Marjo; Matilainen, Markus; Luoma, Amelie; Vuorimaa, Anna; Lehto, Jussi; Laaksonen, Sini; Brockmann, Eeva-Christine; Kuhle, Jens; Leppert, David; Soukka, Tero; Lamminmäki, Urpo; Airas, Laura
Serum glial fibrillary acid protein associates with TSPO-expressing lesions in multiple sclerosis brain (2025) Sjöros, Tanja; Saraste, Maija; Matilainen, Markus; Nylund, Marjo; Koivumäki, Mikko; Kuhle, Jens; Leppert, David; Airas, Laura
Synaptic Density in Multiple Sclerosis (2025)
- Neurology, Neuroimmunology and Neuroinflammation
Luoma, Amelie; Matilainen, Markus; Tuisku, Jouni Mikael; Aarnio, Richard; Nikkilä, Taru; Laaksonen, Sini; Koivumäki, Mikko; Honkonen, Eveliina; Nylund, Marjo; Wahlroos, Saara; Solin, Olof; Chen, Ming-Kai; Toyonaga, Takuya; Lehto, Jussi; Snellman, Anniina; Rinne, Juha O.; Airas, Laura M.
A Novel Comprehensive Epigenomic Liquid Biopsy Assay Reveals Disease Biology in Multiple Sclerosis Patients from 1 mL of Plasma (2024)
- Multiple Sclerosis
Beagan, Jonathan; Nylund, Marjo; Painter, Corrie; Saraste, Maija; Chmielecki, Juliann; Tran, Vy; Tamakloe, Tyrone; Matilainen, Markus; Eaton, Matthew; Barrett, Carl; Airas, Laura
Changing treatment of hip fractures in Finland (2024)
- Archives of Orthopaedic and Trauma Surgery
Leino, Oskari K.; Forsbacka, Nora; Laaksonen, Inari E.; Mäkelä, Keijo T.; Matilainen, Markus; Ekman, Elina M.
Correction to: Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA (EJNMMI Research, (2024), 14, 1, (25), 10.1186/s13550-024-01085-7) (2024)
- EJNMMI Research
Alzghool Obada M., Aarnio Richard, Helin Jatta S., Wahlroos Saara, Keller Thomas, Matilainen Markus, Solis Junel, Danon Jonathan J., Kassiou Michael, Snellman Anniina, Solin Olof, Rinne Juha O., Haaparanta‑Solin Merja
Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA (2024)
- EJNMMI Research
Alzghool Obada M., Aarnio Richard, Helin Jatta S., Wahlroos Saara, Keller Thomas, Matilainen Markus, Solis Junel, Danon Jonathan J., Kassiou Michael, Snellman Anniina, Solin Olof, Rinne Juha O., Haaparanta-Solin Merja
Lonkkamurtumien ilmaantuvuus ja hoito Suomessa 1997-2018 (2024)
- Suomen ortopedia ja traumatologia
Leino, Oskari; Forsbacka, Nora; Laaksonen, Inari; Mäkelä, Keijo; Matilainen, Markus; Ekman, Elina
Plasma CHI3L1 associates with increased TSPO-PET measurable microglial activation in patients with progressive multiple sclerosis (2024)
- Multiple Sclerosis
40th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), 18-20 September 2024, Copenhagen, Denmark Ahola, Venla; Saraste, Maija; Matilainen, Markus; Brockmann, Eeva-Christine; Lamminmaki, Urpo; Airas, Laura
Proximal Humeral Fractures in Finland - Regional Differences in Incidence and Methods of Treatment (2024)
- Journal of Shoulder and Elbow Surgery
Roivas, Ida A,: Leino, Oskari K.; Lehtimäki, Kaisa K.; Matilainen, Markus; Ekman, Elina
Regional variations in incidence and treatment trends of Achilles tendon ruptures in Finland : a nationwide study (2024)
- Acta Orthopaedica
Hallinen, Marjukka; Sallinen, Henri; Keskinen, Heli; Matilainen, Markus; Ekman, Elina
Sex-driven variability in TSPO-expressing microglia in MS patients and healthy individuals (2024)
- Frontiers in Neurology
Laaksonen Sini, Saraste Maija, Nylund Marjo, Hinz Rainer, Snellman Anniina, Rinne Juha, Matilainen Markus, Airas Laura
Stationary subspace analysis based on second-order statistics (2024)
- Journal of Computational and Applied Mathematics
Flumian Lea, Matilainen Markus, Nordhausen Klaus, Taskinen Sara
Synaptic density in multiple sclerosis: An in vivo study using [11C]UCB-J-PET imaging (2024)
- Multiple Sclerosis
Luoma, Amelie; Matilainen, Markus; Tuisku, Jouni; Aarnio, Richard; Nikkila, Taru; Laaksonen, Sini; Koivumaki, Mikko; Honkonen, Eveliina; Nylund, Marjo; Wahlroos, Saara; Toyonaga, Takuya; Chen, Ming-Kai; Lehto, Jussi; Snellman, Anniina; Rinne, Juha; Airas, Laura
TSPO-PET-measurable microglial activity remains unaltered in cladribine-treated RRMS patients (2024)
- Multiple Sclerosis
Rajalehto, Olli; Saraste, Maija; Matilainen, Markus; Nylund, Marjo; Honkonen, Eveliina; Lehto, Jussi; Airas, Laura
Adenosine A2A receptor availability in cerebral gray and white matter of patients with Parkinson's disease (2023)
- Parkinsonism and Related Disorders
Waggan Imran, Rissanen Eero, Tuisku Jouni, Matilainen Markus, Parkkola Riitta, Rinne Juha O, Airas Laura