Maija Itälä-Remes
MD, PhD, Adjunct professor
Haematology; Acute Leukemia; Haematopoietic Stem Cell Transplantation
Academic degrees:
Medical doctor 26.5.1986, University of Turku, Finland
Doctoral thesis (”B-cell Chronic Lymphocytic Leukemia and Increased Susceptibility to Infections”) and 13.9.1996, University of Turku
Doctorate, PhD 4.12.1997, University of Turku
Adjunct professor Internal Medicine/Clinical Haematology 18.4.2005, University of Turku
Professional appointments:
Resident/specialist in Internal Medicine and in Anaesthesia 1986-1997 Turku University Central Hospital.
Clinical haematologist, Turku University Central Hospital 1997-2007.
Medical Adviser, Janssen-Cilag, Nordic Section 2007-2008.
Head of Department of Haematology, Tampere University Central Hospital 2008-2010.
Head of Stem Cell Transplant Unit, Turku University Hospital 2010-2017.
Head of Stem Cell Transplant Unit, Helsinki University Hospital 2017-2018.
Head of Division of Clinical Haematology and Stem Cell Transplant Unit, Programme Director of Stem Cell Transplant Unit, Turku University Central Hospital 2018-
Dissertations:
Supervisor 3, Opponent 2, Reviewer 4
Other academic appontments:
Review of the scientific work for docent application
Appointments in Scientific Societies:
Chair of the Finnish Society of Haematology 2012-2014, member 2014-.
Chair of the Finnish Acute Leukemia Working Group 2015-2018, member 2018-
The Nordic-Dutch Working Group for CLL (Chronic Lymphocytic Leukemia) Group, member 2000-2014.
The Finnish Haematology Registry and Biobank, member of the Steering group 2012-2014.
The European Group for Blood and Marrow Transplantation, member 1997-
Duties with National Authorities:
Consultant of the Parliament (Implementation of EU directives into National legislation) 2006-2007
Consultant of the Ministry of Social Affairs and Health (STM) 2016
Consultant of the Finnish Medicine Agency (Fimea) 2016-2018
EU consultation Brussels 2017
Activities in Quality Management:
Inspector exam of FACT/JACIE Quality Management System 31.5.2011, Rotterdam.
Establishment of the Quality Management System of the Stem Cell Unit of Turku University Hospital 2006; Moderation of initial JACIE accreditation and two re-accreditations 2006-2017 Turku University Central Hospital, Turku.
Scientific publications and text book articles in field of stem cell transplantions and haematological malignancies
Principal Investigator and Sub-investigator of International Multicentre Clinical Trials
GCP training, latest update 22.2.2018
Lectures at Finnish University Hospitals and Central Hospitals
Public lectures
Lectures at International meetings
Education of residents and junior colleagues (Clinical haematology and Stem Cell Transplantations)
Member of Faculty of the International Congress on Stem Cell Transplantation and Cellular Therapies, Berlin 2017
- Copy number alterations define outcome in Philadelphia chromosome-positive acute lymphoblastic leukemia (2022)
- Haematologica
(B1 Non-refereed article in a scientific journal) - Efficacy of conventional-dose cytarabine, idarubicin and thioguanine versus intermediate-dose cytarabine and idarubicin in the induction treatment of acute myeloid leukemia: Long-term results of the prospective randomized nationwide AML-2003 study by the Finnish Leukemia Group (2022)
- European Journal of Haematology
(A1 Refereed original research article in a scientific journal) - Luovuttajan lymfosyytti-infuusiot allogeenisen kantasolujen siirron jälkihoidossa (2022)
- Duodecim
(A1 Refereed original research article in a scientific journal) - Anti-cytokine autoantibodies are rare in chronic graft-versus-host disease (2021)
- Scandinavian Journal of Immunology
(B1 Non-refereed article in a scientific journal) - B-cell receptor stereotyped subsets and outcome for patients with chronic lymphocytic leukemia in the HOVON 68 trial (2021)
- Journal of Translational Genetics and Genomics
(A1 Refereed original research article in a scientific journal) - Discovery of a Novel CIP2A Variant (NOCIVA) with Clinical Relevance in Predicting TKI Resistance in Myeloid Leukemias (2021)
- Clinical Cancer Research
(A1 Refereed original research article in a scientific journal) - Kantasolusiirrot - soluterapia murroksessa (2021)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Seasonal human coronaviruses respiratory tract infection in recipients of allogeneic hematopoietic stem cell transplantation (2021)
- Journal of Infectious Diseases
(A1 Refereed original research article in a scientific journal) - Cytogenetic risk score maintains its prognostic significance inAMLpatients with detectable measurable residual disease undergoing transplantation in remission: On behalf of the acute leukemia working party of the European society for blood and marrow transplantation (2020)
- American Journal of Hematology
(A1 Refereed original research article in a scientific journal) - Meta-Analysis of Genome-Wide Association and Gene Expression Studies Implicates Donor T Cell Function and Cytokine Pathways in Acute GvHD (2020)
- Frontiers in immunology
(A1 Refereed original research article in a scientific journal) - Outcome in patients with diffuse large B-cell lymphoma who relapse after autologous stem cell transplantation and receive active therapy. A retrospective analysis of the Lymphoma Working Party of the European Society for Blood and Marrow Transplantation (EBMT) (2020)
- Bone Marrow Transplantation
(A1 Refereed original research article in a scientific journal) - Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease (2020)
- Nature Communications
(A1 Refereed original research article in a scientific journal) - Total body irradiation plus fludarabine compared to busulfan plus fludarabine as "reduced-toxicity conditioning" for patients with acute myeloid leukemia treated with allogeneic hematopoietic cell transplantation in first complete remission: a study by the Acute Leukemia Working Party of the EBMT (2020)
- Bone Marrow Transplantation
(A1 Refereed original research article in a scientific journal) - Arpp19 Promotes Myc and Cip2a Expression and Associates with Patient Relapse in Acute Myeloid Leukemia (2019)
- Cancers
(A1 Refereed original research article in a scientific journal) - Comparative Outcomes of Myeloablative and Reduced-Intensity Conditioning Allogeneic Hematopoietic Cell Transplantation for Therapy-Related Acute Myeloid Leukemia with Prior Solid Tumor: a report from the ALWP of the EBMT (2019)
- American Journal of Hematology
(A1 Refereed original research article in a scientific journal) - Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCT (2019)
- Frontiers in immunology
(A1 Refereed original research article in a scientific journal) - EBMT prospective observational study on allogeneic hematopoietic stem cell transplantation in T-prolymphocytic leukemia (T-PLL) (2019)
- Bone Marrow Transplantation
(A1 Refereed original research article in a scientific journal) - Genomic prediction of relapse in recipients of allogeneic haematopoietic stem cell transplantation (2019)
- Leukemia
(A1 Refereed original research article in a scientific journal) - Gonadal Function after Busulfan Compared with Treosulfan in Children and Adolescents Undergoing Allogeneic Hematopoietic Stem Cell Transplant (2019)
- Biology of Blood and Marrow Transplantation
(A1 Refereed original research article in a scientific journal) - Haploidentical Stem Cell Transplantation with Posttransplant Cyclophosphamide Therapy vs Other Donor Transplantations in Adults with Hematologic Cancers: A Systematic Review and Meta-analysis (2019)
- JAMA Oncology
(A1 Refereed original research article in a scientific journal)