Georgy Belogurov
PhD
gebelo@utu.fi +358 29 450 4775 +358 50 475 7149 Tykistökatu 6 Turku Office: 6057 ORCID identifier: https://orcid.org/0000-0002-3070-6843 |
Transcription, nucleic acids enzymes, enzyme kinetics, protein chemistry, molecular modeling, nucleoside analogue inhibitors, phylogenomics.
Ph.D. - University of Turku, Dept. of Biochemistry, Finland, 2005
Postdoc - Ohio State Univesity, Dept. of Microbiology, USA, 2006-2009
Principal investigator - University of Turku, Dept. of Biochemistry, Finland, 2009-2020
Principal investigator - University of Turku, Dept. of Life Technologies, Finland, 2020-
Associate Professor - University of Turku, Dept. of Life Technologies, Finland, 2023-
The properties of a cell are determined by the information encoded in its genome. Understanding how such information is differentially and dynamically retrieved in response to environmental changes and cellular needs is a major challenge facing molecular biology. The focal point of our research is a multisubunit RNA polymerase, the enzyme that carries out the first step in gene expression, synthesis of RNA. We study several classes of RNA polymerases with the aim of understanding the fundamental aspects of transcription regulation, catalytic mechanism, and developing medically relevant transcription inhibitors.
Molecular Biology, Bioproduction, Bioinformatics, Enzyme kinetics
- Catalytically important ionizations along the reaction pathway of yeast pyrophosphatase (2000)
- Biochemistry
(A1 Refereed original research article in a scientific journal)
