Tharun Kotammagari
PhD
tkkota@utu.fi Office: Aurum ORCID identifier: https://orcid.org/0000-0003-1288-0124 |
Carbohydrate Chemistry, Biomimetic synthesis, Modified nucleosides, Oligonucleotide chemistry, Nucleic acids, metalated oligonucleotides, hybridization probes
I was born and raised in Nandyal (Andhra Pradesh), India. I pursued my master's degree in organic chemistry at the Jawaharlal Nehru Technological University, Anantapur, India. I received my Ph.D. in chemical science from the CSIR-National Chemical Laboratory, Pune, India. Where my research was focused on the biomimetic total Synthesis of complex natural products mainly bioactive lactones from carbohydrate scaffolds and Artemisinic acid glycoconjugates synthesis. I later moved to the University at Albany, State University of New York (SUNY), USA for my postdoctoral research, where I worked on α-functionalization of Cysteine type amino acids with various alkyl halides using photocatalysis and dimeric compounds synthesis through dearomatization reactions. After that, I spent a year working as an Associate Scientist at GVK Biosciences, a CRO based in Hyderabad, India. I am currently working as a TCSMT postdoctoral researcher at the Department of chemistry, University of Turku, Finland. My research focuses on the synthesis of modified nucleosides, oligonucleotides, metallated oligonucleotides, and their conjugation to develop hybridization probes.
Modified nucleosides and nucleic acids, Oligonucleotide chemistry, developing covalently mercurated hybridization probes.
- An accelerated Rauhut-Currier dimerization enabled synthesis of (±)-Incarvilleatone and anticancer studies (2023)
- Beilstein Journal of Organic Chemistry
(Refereed journal article or data article (A1)) - An accelerated Rauhut-Currier dimerization enabled synthesis of (±)-Incarvilleatone and anticancer studies (2022) Kotammagari TK, Misra S, Paul S, Kunte S, Gonnade RG, Santra MK, Bhattacharya AK
(Other (O2)) - Oligonucleotides Featuring a Covalently Mercurated 6-Phenylcarbazole Residue as High-Affinity Hybridization Probes for Thiopyrimidine-Containing Sequences (2022)
- Chemistry - A European Journal
(Refereed journal article or data article (A1)) - Synthesis of artemisinic acid derived glycoconjugates and their anticancer studies (2020)
- Organic and Biomolecular Chemistry
(Refereed journal article or data article (A1)) - Synthesis of artemisinin derived glycoconjugates inspired by click chemistry (2019)
- New Journal of Chemistry
(Refereed journal article or data article (A1)) - Unusual Epimerization in Styryllactones: Synthesis of (-)-5-Hydroxygoniothalamin, (-)-5-Acetylgoniothalamin, and O-TBS-Goniopypyrone (2019)
- ACS Omega
(Refereed journal article or data article (A1)) - Biomimetic Total Synthesis of Angiopterlactone B and Other Potential Natural Products (2017)
- Organic Letters
(Refereed journal article or data article (A1)) - Synthesis of naturally occurring (+)-osmundalactone and 4-epi-(+)-osmundalactone from triacetyl-O-D-glucal (2015)
- Tetrahedron Letters
(Refereed journal article or data article (A1)) - 2,4,6-Trichlorobenzoyl Chloride (Yamaguchi Reagent) (2014)
- Synlett
(Article or data-article in scientific journal (B1))