Anu Airaksinen - UTU Research Portal

Anu Airaksinen

- Professor,
Turku PET Centre (Independent units)

Turku PET Centre

anu.airaksinen@utu.fi

+358 29 450 2199

+358 50 470 7622

Radiopharmaceutical Chemistry Research Group

radiopharmaceutical chemistry; PET radiochemistry; image guided drug delivery; pretargeted PET imaging; theranostics; nanotheranostics

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Comparison of Ga-68-DOTA-Siglec-9 and F-18-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry (2017)
- Contrast Media and Molecular Imaging
Virtanen H, Silvola JMU, Autio A, Li XG, Liljenback H, Hellberg S, Siitonen R, Stahle M, Kakela M, Airaksinen AJ, Helariutta K, Tolvanen T, Veres TZ, Saraste A, Knuuti J, Jalkanen S, Roivainen A, Roivainen A
Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling (2017)
- Small
Ferreira MPA, Ranjan S, Kinnunen S, Correia A, Talman V, Mäkilä E, Barrios-Lopez B, Kemell M, Balasubramanian V, Salonen J, Hirvonen J, Ruskoaho H, Airaksinen AJ, Santos HA
Pretargeted PET Imaging of trans-Cyclooctene-Modified Porous Silicon Nanoparticles (2017)
- ACS Omega
Keinanen O, Makila EM, Lindgren R, Virtanen H, Liljenback H, Oikonen V, Sarparanta M, Molthoff C, Windhorst AD, Roivainen A, Salonen JJ, Airaksinen AJ
Pretargeting of internalizing trastuzumab and cetuximab with a F-18-tetrazine tracer in xenograft models (2017)
- EJNMMI Research
Keinanen O, Fung K, Pourat J, Jallinoja V, Vivier D, Pillarsetty NK, Airaksinen AJ, Lewis JS, Zeglis BM, Sarparanta M
Adenoviral Delivery of Tumor Necrosis Factor-alpha and Interleukin-2 Enables Successful Adoptive Cell Therapy of Immunosuppressive Melanoma (2016)
- Molecular Therapy
Siurala M, Havunen R, Saha D, Lumen D, Airaksinen AJ, Tähtinen S, Cervera-Carrascon V, Bramante S, Parviainen S, Vähä-Koskela M, Kanerva A, Hemminki A
A new highly reactive and low lipophilicity fluorine-18 labeled tetrazine derivative for pretargeted PET imaging (2016)
- ACS Medicinal Chemistry Letters
Outi Keinänen, Xiang-Guo Li, Naveen K Chenna, Dave Lumen, Jennifer Ott, Carla FM Molthoff, Mirkka Sarparanta, Kerttuli Helariutta, Tapani Vuorinen, Albert D Windhorst, Anu J Airaksinen
Comparison of Somatostatin Receptor 2-Targeting PET Tracers in the Detection of Mouse Atherosclerotic Plaques (2016)
- Molecular Imaging and Biology
Petteri Rinne, Sanna Hellberg, Max Kiugel, Jenni Virta, Xiang-Guo Li, Meeri Käkelä, Kerttuli Helariutta, Pauliina Luoto, Heidi Liljenbäck, Harri Hakovirta, Maria Gardberg, Anu J. Airaksinen, Juhani Knuuti, Antti Saraste, Anne Roivainen
In vitro and in vivo assessment of heart-homing porous silicon nanoparticles (2016)
- Biomaterials
Mónica P.A. Ferreira, Sanjeev Ranjan, Alexandra M.R. Correia, Ermei M. Mäkilä, Sini M. Kinnunen, Hongbo Zhang, Mohammad-Ali Shahbazi, Patrick V. Almeida, Jarno J. Salonen, Heikki J. Ruskoaho, Anu J. Airaksinen, Jouni T. Hirvonen, Hélder A. Santos
MICROLOCALIZED TRANSPORT OF AGENTS INTO ARTICULAR CARTILAGE USING HIGH INTENSITY ULTRASOUND (2016)
- Osteoarthritis and Cartilage
Nieminen HJ, Lampsijärvi E, Salmi A, Airaksinen A, Saarakkala S, Pritzker KP, Haeggström E
Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor (2015)
- Cancer Immunology Research
Tahtinen S, Gronberg-Vaha-Koskela S, Lumen D, Merisalo-Soikkeli M, Siurala M, Airaksinen AJ, Vaha-Koskela M, Hemminki A
Combination of adenovirus and adoptive T-cell therapy breaks tumor tolerance by recruiting immune cells to and promoting their activity in the tumor (2015)
- Cancer Immunology Research
Tahtinen S, Gronberg-Vaha-Koskela S, Lumen D, Siurala M, Airaksinen AJ, Vaha-Koskela M, Hemminki A
Dual Indium-111 and Fluorescent Labeling of iRGD-Targeted Undecylenic-acid -modified Thermally Hydrocarbonized Porous Silicon (UnTHCPSi) Particles for Drug Delivery System Evaluation In Vivo (2015)
- Journal of Labelled Compounds and Radiopharmaceuticals
Sarparanta M, Wang CF, Makila E, Hyvonen M, Laakkonen P, Salonen J, Hirvonen J, Santos H, Airaksinen AJ
Multifunctional porous silicon nanoparticles for cancer theranostics (2015)
- Biomaterials
Chang-Fang Wang, Mirkka P. Sarparanta, Ermei M. Mäkilä, Maija L.K. Hyvönen, Pirjo M. Laakkonen, Jarno J. Salonen, Jouni T. Hirvonen, Anu J. Airaksinen, Hélder A. Santos
Oncolytic Adenovirus Breaks Tumor Tolerance To Adoptive T-Cell Therapy By Recruiting Immune Cells To and Promoting Their Activity in the Tumor (2015)
- Molecular Therapy
Tahtinen S, Gronberg-Vaha-Koskela S, Lumen D, Merisalo-Soikkeli M, Siurala M, Airaksinen AJ, Vaha-Koskela M, Hemminki A
Oxidative Stress Protection by Exogenous Delivery of rhHsp70 Chaperone to the Retinal Pigment Epithelium (RPE), a Possible Therapeutic Strategy Against RPE Degeneration (2015)
- Pharmaceutical Research
Subrizi A, Toropainen E, Ramsay E, Airaksinen AJ, Kaarniranta K, Urtti A
SPECT/CT imaging and ex vivo biodistribution of peptide modified In-111-labelled Silicon nanoparticles in a rat model of myocardial infarction (2015)
- Journal of Labelled Compounds and Radiopharmaceuticals
Ranjan S, Ferreira M, Kinnunen S, Balasubramanian V, Muje S, Correia A, Makila E, Talman V, Salonen J, Hirvonen J, Ruskoaho H, Santos H, Airaksinen AJ
Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists (2015)
- European Journal of Pharmaceutical Sciences
Yrjola S, Sarparanta M, Airaksinen AJ, Hytti M, Kauppinen A, Pasonen-Seppanen S, Adinolfi B, Nieri P, Manera C, Keinanen O, Poso A, Nevalainen TJ, Parkkari T
Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake (2014)
- Biomaterials
Wang C-, Mäkilä EM, Kaasalainen MH, Liu D, Sarparanta MP, Airaksinen AJ, Salonen JJ, Hirvonen JT, Santos HA
Detection of atherosclerotic plaques with a novel vascular adhesion protein-1 targeting [18F]FDR-Siglec-9 peptide (2014)
- Journal of Nuclear Medicine
Johanna MU Silvola, Helena Ahtinen, Xiang-Guo Li, Sanna Hellberg, Heidi Liljenbäck, Anu J. Airaksinen, Sirpa Jalkanen, Juhani Knuuti, Antti Saraste, Anne Roivainen
In vivo evaluation of porous silicon and porous silicon solid lipid nanocomposites for passive targeting and imaging (2014)
- Molecular Pharmaceutics
Annukka M. Kallinen, Mirkka P. Sarparanta, Dongfei Liu, Ermei M. Mäkilä, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos, Anu J. Airaksinen