Anu Airaksinen - UTU Research Portal

Anu Airaksinen

- Professor,
Turku PET Centre (Independent units)

Turku PET Centre

anu.airaksinen@utu.fi

+358 29 450 2199

+358 50 470 7622

Radiopharmaceutical Chemistry Research Group

radiopharmaceutical chemistry; PET radiochemistry; image guided drug delivery; pretargeted PET imaging; theranostics; nanotheranostics

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Exploring the Biochemical Foundations of a Successful GLUT1-Targeting Strategy to BNCT: Chemical Synthesis and In Vitro Evaluation of the Entire Positional Isomer Library of ortho-Carboranylmethyl-Bearing Glucoconjugates (2021)
- Molecular Pharmaceutics
Matovic Jelena, Järvinen Juulia, Sokka Iris K, Imlimthan Surachet, Raitanen Jan-Erik, Montaser Ahmed, Maaheimo Hannu, Huttunen Kristiina M, Peräniemi Sirpa, Airaksinen Anu J, Sarparanta Mirkka, Johansson Mikael P, Rautio Jarkko, Ekholm Filip S
First-in-Human Study of 68 Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1 (2021)
- Journal of Nuclear MedicineContrast Media and Molecular Imaging
Viitanen Riikka, Moisio Olli Antero, Lankinen Petteri, Li Xiang-Guo, Koivumäki Mikko, Suilamo Sami, Tolvanen Tuula, Taimen Kirsi, Mali Markku, Kohonen Ia, Koskivirta Ilpo, Oikonen Vesa, Virtanen Helena, Santalahti Kristiina, Autio Anu, Saraste Antti, Pirilä Laura, Nuutila Pirjo, Knuuti Juhani, Jalkanen Sirpa, Roivainen Anne
Investigation of silicon nanoparticles produced by centrifuge chemical vapor deposition for applications in therapy and diagnostics (2021)
- European Journal of Pharmaceutics and Biopharmaceutics
Lumen Dave, Wang Shiqi, Mäkilä Ermei, Imlimthan Surachet, Sarparanta Mirkka, Correia Alexandra, Westerveld Haug Christina, Hirvonen Jouni, Santos Hélder A, Airaksinen Anu J, Filtvedt Werener, Salonen Jarno
Radiolabeling of Theranostic Nanosystems (2021) Bio-Nanomedicine for Cancer Therapy Das Sudeep, Imlimthan Surachet, Airaksinen Anu J., Sarparanta Mirkka
Addressing the Biochemical Foundations of a Glucose-Based "Trojan Horse"-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment (2020)
- Molecular Pharmaceutics
Jelena Matović, Juulia Järvinen, Helena C. Bland, Iris K. Sokka, Surachet Imlimthan, Ruth Mateu Ferrando, Kristiina M. Huttunen, Juri Timonen, Sirpa Peräniemi, Olli Aitio, Anu J. Airaksinen, Mirkka Sarparanta, Mikael P. Johansson, Jarkko Rautio, Filip S. Ekholm
Comparison of Clinically Relevant Oncolytic Virus Platforms for Enhancing T Cell Therapy of Solid Tumors (2020)
- Molecular Therapy - Oncolytics
Victor Cervera-Carrascon, Dafne C.A. Quixabeira, Riikka Havunen, Joao M. Santos, Emma Kutvonen, James H.A. Clubb, Mikko Siurala, Camilla Heiniö, Sadia Zafar, Teija Koivula, Dave Lumen, Marjo Vaha, Arturo Garcia-Horsman, Anu J.Airaksinen, Suvi Sorsa, Marjukka Anttila, Veijo Hukkanen, Anna Kanerva, Akseli Hemminki
Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke (2020)
- Biomaterials
Vimalkumar Balasubramanian, Andrii Domanskyi, Juho-Matti Renko, Mirkka Sarparanta, Chang-Fang Wang, Alexandra Correia, Ermei Mäkilä, Osku S. Alanen, Jarno Salonen, Anu J. Airaksinen, Raimo Tuominen, Jouni Hirvonen, Mikko Airavaara, Hélder A. Santos
Evaluation of organo [18F]fluorosilicon tetrazine as a prosthetic group for the synthesis of PET radiotracers (2020)
- Molecules
Sofia Otaru, Surachet Imlimthan, Mirkka Sarparanta, Kerttuli Helariutta, Kristiina Wähälä, Anu J. Airaksinen
Hexosome engineering for targeting of regional lymph nodes (2020)
- Materialia
Helvig SY, Andersen H, Antopolsky M, Airaksinen AJ, Urtti A, Yaghmur A, Moghimi SM
Metabolism of a Bioorthogonal PET Tracer Candidate [F-19/F-18]SiFA-Tetrazine in Mouse Liver Microsomes: Biotransformation Pathways and Defluorination Investigated by UHPLC-HRMS (2020)
- Molecular Pharmaceutics
Otaru S, Niemikoski H, Sarparanta M, Airaksinen AJ
Preparation and in vivo evaluation of red blood cell membrane coated porous silicon nanoparticles implanted with Tb-155 (2020)
- Nuclear Medicine and Biology
Ulrika Jakobsson, Ermei Mäkilä, Antti Rahikkala, Surachet Imlimthan, Jarkko Lampuoti, Sanjeev Ranjana, Jouni Heino, Pasi Jalkanen, Ulli Köster, Kenichiro Mizohata, Hélder A. Santos, Jarno Salonen, Anu J. Airaksinen, Mirkka Sarparanta, Kerttuli Helariutta
Systematic in vitro biocompatibility studies of multimodal cellulose nanocrystal and lignin nanoparticles (2020)
- Journal of Biomedical Materials Research Part A
Imlimthan S, Correia A, Figueiredo P, Lintinen K, Balasubramanian V, Airaksinen AJ, Kostiainen MA, Santos HA, Sarparanta M
Intravitreal Pharmacokinetics in Mice: SPECT/CT Imaging and Scaling to Rabbits and Humans (2019)
- Molecular Pharmaceutics
Schmitt M, Hippeläinen E, Ravina M, Arango-Gonzalez B, Antopolsky M, Vellonen KS, Airaksinen AJ, Urtti A
Localized delivery of compounds into articular cartilage by using high-intensity focused ultrasound (2019)
- Scientific Reports
Nieminen HJ, Lampsijarvi E, Barreto G, Finnila MAJ, Salmi A, Airaksinen AJ, Eklund KK, Saarakkala S, Pritzker KPH, Haeggstrom E
Porous silicon as a platform for radiation theranostics together with a novel RIB-based radiolanthanoid (2019)
Helariutta K., Jakobsson U., Mäkilä E., Airaksinen A., Alanen O., Etilé A., Köster U., Ranjan S., Salonen J., Santos H.
Radiolabeled Molecular Imaging Probes for the In Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications (2019)
- Biomacromolecules
Imlimthan S, Otaru S, Keinanen O, Correia A, Lintinen K, Santos HA, Airaksinen AJ, Kostiainen MA, Sarparanta M
Recycling of O-18 enriched water used in F-18 cyclotron production (2019)
- Applied Radiation and Isotopes
Todorov B, Belovezhdova I, Alanen O, Airaksinen AJ, Djingova R
Site-Specific In-111-Radiolabeling of Dual-PEGylated Porous Silicon Nanoparticles and Their In Vivo Evaluation in Murine 4T1 Breast Cancer Model (2019)
- Pharmaceutics
Dave Lumen, Simo Näkki, Surachet Imlimthan, Elisavet Lambidis, Mirkka Sarparanta, Wujun Xu,Vesa-Pekka Lehto, Anu J. Airaksinen
Synthesis and biological evaluation of [F-18]fluorovinpocetine, a potential PET radioligand for TSPO imaging (2019)
- Bioorganic and Medicinal Chemistry Letters
Nag S, Krasikova R, Airaksinen AJ, Arakawa R, Petukhovd M, Gulyas B
Abscopal Effect in Non-injected Tumors Achieved with Cytokine-Armed Oncolytic Adenovirus (2018)
- Molecular Therapy - Oncolytics
Havunen R, Santos JM, Sorsa S, Rantapero T, Lumen D, Siurala M, Airaksinen AJ, Cervera-Carrascon V, Tähtinen S, Kanerva A, Hemminki A