Aleksi Tornio - UTU Research Portal

Aleksi Tornio

- Associate Professor,
Institute of Biomedicine (Faculty of Medicine)

aleksi.tornio@utu.fi

+358 29 450 4608

+358 50 476 5715

Kiinamyllynkatu 10

Turku

ORCID identifier: https://orcid.org/0000-0001-5713-5692

Areas of expertise

Clinical Pharmacology; Pharmacokinetics; Drug-drug interactions; Pharmacogenetics

Publications

7 of 9

Cytochrome P450 in Pharmacogenetics: An Update (2018)
- Advances in Pharmacology
Tornio A, Backman JT
(C1 Refereed scientific book)
Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects (2018)
- Basic and Clinical Pharmacology and Toxicology
Neuvonen M, Tarkiainen EK, Tornio A, Hirvensalo P, Tapaninen T, Paile-Hyvarinen M, Itkonen MK, Holmberg MT, Karja V, Mannisto VT, Neuvonen PJ, Pihlajamaki J, Backman JT, Niemi M
(A1 Refereed original research article in a scientific journal)
Implications of intercorrelation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: a case study with repaglinide (2018)
- British Journal of Clinical Pharmacology
Doki K, Darwich AS, Achour B, Tornio A, Backman JT, Rostami-Hodjegan A
(A1 Refereed original research article in a scientific journal)
Investigating Real-World Clopidogrel Pharmacogenetics in Stroke Using a Bioresource Linked to Electronic Medical Records (2018)
- Clinical Pharmacology and Therapeutics
Tornio A, Flynn R, Morant S, Velten E, Palmer CNA, MacDonald TM, Doney ASF
(A1 Refereed original research article in a scientific journal)
Response to "Influence of Diabetes on Antiplatelet Drug Efficacy" (2018) Tornio A, Palmer CNA, Doney ASF
(Other publication)
A commonmissense variant of LILRB5 is associated with statin intolerance andmyalgia (2017)
- European Heart Journal
Siddiqui MK, Maroteau C, Veluchamy A, Tornio A, Tavendale R, Carr F, Abelega NU, Carr D, Bloch K, Hallberg P, Yue QY, Pearson ER, Colhoun HM, Morris AD, Dow E, George J, Pirmohamed M, Ridker PM, Doney ASF, Alfirevic A, Wadelius M, Maitland-van der Zee AH, Chasman DI, Palmer CNA
(A1 Refereed original research article in a scientific journal)
Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters (2017)
- Expert Opinion on Drug Metabolism and Toxicology
Tornio A, Neuvonen PJ, Niemi M, Backman JT
(A2 Refereed review article in a scientific journal )
Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone (2016)
- Drug Metabolism and Disposition
Itkonen MK, Tornio A, Neuvonen M, Neuvonen PJ, Niemi M, Backman JT
(A1 Refereed original research article in a scientific journal)
High Frequency of CYP2D6 Ultrarapid Metabolizer Genotype in the Finnish Population (2016)
- Basic and Clinical Pharmacology and Toxicology
Pietarinen P, Tornio A, Niemi M
(A1 Refereed original research article in a scientific journal)
Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans (2015)
- Clinical Pharmacology and Therapeutics
Tarkiainen EK, Holmberg MT, Tornio A, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M
(A1 Refereed original research article in a scientific journal)