Aleksi Tornio
aleksi.tornio@utu.fi +358 29 450 4608 +358 50 476 5715 Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0001-5713-5692 |
Areas of expertise
Clinical Pharmacology; Pharmacokinetics; Drug-drug interactions; Pharmacogenetics
Clinical Pharmacology; Pharmacokinetics; Drug-drug interactions; Pharmacogenetics
Publications 
3 of 5
- Performance of plasma coproporphyrin I and III as OATP1B1 biomarkers in humans (2021)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - Sex-Based Outcomes After Coronary Artery Bypass Grafting (2021)
- Annals of Thoracic Surgery
(A1 Refereed original research article in a scientific journal) - Effect of High-Dose Esomeprazole on CYP1A2, CYP2C19, and CYP3A4 Activities in Humans: Evidence for Substantial and Long-lasting Inhibition of CYP2C19 (2020)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - Febuxostat, But Not Allopurinol, Markedly Raises the Plasma Concentrations of the Breast Cancer Resistance Protein Substrate Rosuvastatin (2020)
- Clinical and Translational Science
(A1 Refereed original research article in a scientific journal) - Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers (2020)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - Placental transporter-mediated drug interactions and offspring congenital anomalies (2020)
- British Journal of Clinical Pharmacology
(A1 Refereed original research article in a scientific journal) - UGT1A3 and Sex Are Major Determinants of Telmisartan Pharmacokinetics-A Comprehensive Pharmacogenomic Study (2020)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation (2019)
- Clinical Pharmacology and Therapeutics
(A2 Refereed review article in a scientific journal ) - Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans (2019)
- Drug Metabolism and Disposition
(A1 Refereed original research article in a scientific journal) - Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel (2019)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - CYP3A4*22 Impairs the Elimination of Ticagrelor, But Has No Significant Effect on the Bioactivation of Clopidogrel or Prasugrel (2019)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - Enantiospecific Pharmacogenomics of Fluvastatin (2019)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - Farmakogenetiikan merkitys lääkehoidolle (2019) Lääketieteellinen farmakologia ja toksikologia Mikko Niemi, Miia Turpeinen, Aleksi Tornio
(D2 Article in a professional compilation book) - Farmakokinetiikkaan vaikuttavat perintötekijät (2019) Lääketieteellinen farmakologia ja toksikologia Mikko Niemi, Miia Turpeinen, Aleksi Tornio
(D2 Article in a professional compilation book) - Itraconazole Increases Ibrutinib Exposure 10-Fold and Reduces Interindividual Variation-A Potentially Beneficial Drug-Drug Interaction (2019)
- Clinical and Translational Science
(A1 Refereed original research article in a scientific journal) - Muut lääkevasteeseen vaikuttavat perintötekijät (2019) Lääketieteellinen farmakologia ja toksikologia Mikko Niemi, Miia Turpeinen, Aleksi Tornio
(D2 Article in a professional compilation book) - Response to "Interaction of Dasabuvir With Clopidogrel: Did Predictions by Physiologically Based Pharmacokinetics Modeling Pass the Test?" (2019) Itkonen MK, Tornio A, Lapatto-Reiniluoto O, Neuvonen M, Neuvonen PJ, Niemi M, Backman JT
(Other publication) - Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans (2018)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal) - Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions (2018)
- Drug Metabolism and Disposition
(A1 Refereed original research article in a scientific journal) - Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics (2018)
- Clinical Pharmacology and Therapeutics
(A1 Refereed original research article in a scientific journal)
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