Virpi Talman
PhD (Pharm), Title of Docent
virpi.talman@utu.fi +358 29 450 2952 +358 50 590 6676 : C639 |
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- Protein kinase C (PKC) as drug target — design, synthesis, structure-activity relationships and pharmacology of novel C1 domain ligands (2014)
- Dosis
- The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cells (2013)
- Pharmacological Research
- C1 domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cells (2011)
- PLoS ONE
- Current status and future prospects of C1 domain ligands as drug candidates (2011)
- Current Topics in Medicinal Chemistry
- Stereoselective synthesis of (3-aminodecahydro-1,4-methanonaphthalen-2-yl) methanols targeted to the C1 domain of protein kinase C (2011)
- Tetrahedron
- Design, Synthesis, and Biological Activity of Isophthalic Acid Derivatives Targeted to the C1 Domain of Protein Kinase C (2009)
- Journal of Medicinal Chemistry
- Screening of natural compounds and their derivatives as potential protein kinase C inhibitors (2004)
- Drug Development Research
UTU Research Portal