MD, PhD, Professor Emeritus Mika Scheinin - UTU Research Portal

Mika Scheinin
MD, PhD, Professor Emeritus

Institute of Biomedicine (Faculty of Medicine)

mschein@utu.fi

: https://orcid.org/0000-0001-7579-9126

Bioanalytics; Clinical Pharmacology; Drug Development; Positron Emission Tomography; Research Ethics

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Involvement of α2-adrenoceptor subtypes A and C in glucose homeostasis and adrenaline-induced hyperglycaemia. (2012)
- NeuroendocrinologyEuropean Journal of Pain
Ruohonen ST, Ruohonen S, Gilsbach R, Savontaus E, Scheinin M, Hein L
Lääkeaineiden vaikutusmekanismit: reseptorit (2012) Farmakologia ja toksikologia Scheinin Mika
Might the observed α2A-adrenoceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? (2012)
- Bioorganic and Medicinal Chemistry
Diamanti Eleonora, Del Bello Fabio, Carbonara Giuseppe, Carrieri Antonio, Fracchiolla Giuseppe, Giannella Mario, Mammoli Valerio, Piergentili Alessandro, Pohjanoksa Katariina, Quaglia Wilma, Scheinin Mika, Pigini Maria
Pharmacokinetics of [F-18]flutemetamol in wild-type rodents and its binding to beta amyloid deposits in a mouse model of Alzheimer's disease (2012)
- European Journal of Nuclear Medicine and Molecular ImagingBiochemical Pharmacology
Snellman A, Rokka J, Lopez-Picon FR, Eskola O, Wilson I, Farrar G, Scheinin M, Solin O, Rinne JO, Haaparanta-Solin M
Synthesis and biological activities of 2- [(heteroaryl)methyl]imidazolines (2012)
- Bioorganic and Medicinal Chemistry
Saczewski Jaroslaw, Hudson Alan, Scheinin Mika, Rybcynska Apolonia, Ma Daqing, Saczewski Franciszek, Laird Shayna, Laurila Jonne M, Boblewski Konrad, Lehmann Artur, Gu Jianteng, Watts Helena
Synthesis and biological activities of 2-[(heteroaryl)methyl]imidazolines (2012)
- Bioorganic and Medicinal Chemistry
Saczewski J, HUDSON A, SCHEININ M, RYBCZYNSKA A, MA DQ, SACZEWSKI F, LAIRD S, LAURILA JM, Boblewski K, LEHMANN A, GU JT, WATTS H
Tietoruutu L2. Lääkeaineiden sitoutuminen reseptoriin (2012) Farmakologia ja toksikologia Scheinin Mika
3-[(Imidazolidin-2-yl)imino]indazole ligands with selectivity for the ?2-adrenoceptor compared to the imidazoline I1 receptorHomogeneous GTP binding assay employing QRET technology (2011)
- Bioorganic and Medicinal ChemistryJournal of Biomolecular Screening
Saczewski Franciszek, Kornicka Anita, Hudson Alan L, Laird Shayna, Scheinin Mika, Laurila Jonne M, Rybczynska Apolonia, Boblewski Konrad, Lehmann Artur, Gdaniec Maria
alpha(2)-Adrenoceptor Regulation of Blood Glucose Homeostasis (2011)
- Basic and Clinical Pharmacology and Toxicology. Supplement
Fagerholm V, Haaparanta M, Scheinin M
Dietary sodium modulates the interaction between efferent and afferent renal nerve activity by altering activation of α2-adrenoceptors on renal sensory nerves (2011)
- AJP - Regulatory, Integrative and Comparative Physiology
Kopp UC, Cicha MZ, Smith LA, Ruohonen S, Scheinin M, Fritz N, Hökfelt T
Different metabolic responses of human brown adipose tissue to activation by cold and insulin (2011)
- Cell Metabolism
Janne Orava, Pirjo Nuutila, Martin E Lidell, Vesa Oikonen, Tommi Noponen, Tapio Viljanen, Mika Scheinin, Markku Taittonen, Tarja Niemi, Sven Enerbäck, Kirsi A Virtanen
Dorsal hand vein responses to the α₁-adrenoceptor agonist phenylephrine do not predict responses to the α₂-adrenoceptor agonist dexmedetomidine. (2011)
- European Journal of Pharmacology
Posti JP, Valve L, Ruohonen S, Akkila J, Scheinin M, Snapir A
Genetic Variations in the ?2A-Adrenoreceptor Are Associated With Blood Pressure Response to the Agonist Dexmedetomidine (2011)
- Circulation: Cardiovascular Genetics
Kurnik Daniel, Muszkat Mordechai, Li Chun, Sofowora Gbenga G, Friedman Eitan A, Scheinin Mika, Wood Alastair J J, Stein C Michael
Involvement of the first transmembrane segment of human alpha(2)-adrenoceptors in the subtype-selective binding of chlorpromazine, spiperone and spiroxatrine (2011)
- British Journal of Pharmacology
Laurila JMM, Wissel G, Xhaard H, Ruuskanen JO, Johnson MS, Scheinin M
Kliinisten lääketutkimusten etiikka (2011) Kliininen farmakologia ja lääkehoito Scheinin Mika, Halila Ritva
Antinociceptive Synergism of MD-354 and Clonidine. Part II. The alpha(2)-Adrenoceptor Component (2010)
- Basic and Clinical Pharmacology and Toxicology. Supplement
Young S, Vainio M, Scheinin M, Dukat M
Effects of variation in the human alpha2A- and alpha2C-adrenoceptor genes on cognitive tasks and pain perception (2010)
Kohli U, Muszkat M, Sofowora G G, Harris P A, Friedman E A, Dupont W D, Scheinin M, Wood A J, Stein C M, Kurnik D
Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report (2010)
- Journal of Medical Case Reports
Iirola T, Laitio R, Kentala E, Aantaa R, Kurvinen J-P, Scheinin M, Olkkola KT
(2010)
Rozwandowicz-Jansen A, Laurila J, Martikkala E, Frang H, Hemmilä I, Scheinin M, Hänninen P, Härmä H
Identification of a novel 12-nucleotide insertion polymorphism in the promoter region of ADRA2B: full linkage with the 9-nucleotide deletion in the coding region and influence on transcriptional activity (2010)
Crassous P A, Blaise R, Marquette A, Snapir A, Scheinin M, Paris H, Schaak S