Mika Scheinin
 MD, PhD, Professor Emeritus

Publications

  

  

  

20 of 25

  

  

  

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• Potentiation of Glibenclamide Hypoglycaemia in Mice by MK-467, a Peripherally Acting Alpha2-Adrenoceptor Antagonist  (2015)  
  • Basic and Clinical Pharmacology and Toxicology
   Ruohonen ST, Ranta-Panula V, Bastman S, Chrusciel P, Scheinin M, Streng T
  (A1 Refereed original research article in a scientific journal)

  
  

• Sensitivity of [C-11]ORM-13070 to increased extracellular noradrenaline in the CNS - a PET study in human subjects  (2015)  
  • Psychopharmacology
   Lehto J, Johansson J, Vuorilehto L, Luoto P, Arponen E, Scheinin H, Rouru J, Scheinin M
  (A1 Refereed original research article in a scientific journal)

  
  

• Test-retest reliability of (11)C-ORM-13070 in PET imaging of α2C-adrenoceptors in vivo in the human brain  (2015)  
  • European Journal of Nuclear Medicine and Molecular Imaging
   Jussi Lehto, Jere R. Virta, Vesa Oikonen, Anne Roivainen, Pauliina Luoto, Eveliina Arponen, Semi Helin, Johanna Hietamäki, Aila Holopainen, Marita Kailajärvi, Juha M. Peltonen, Juha Rouru, Jukka Sallinen, Kirsi Virtanen, Iina Volanen, Mika Scheinin, Juha O. Rinne
  (A1 Refereed original research article in a scientific journal)

  
  

• Transparency and Registration in Clinical Research in the Nordic Countries – Nordic Trial Alliance report, NordForsk  (2015)   Skoog M, Saarimäki JM, Gluud C, Scheinin M, Erlendsson K, Aamdal S, Cabral Iversen V, Mørkved S, Englund M, Jacobsson E-C
  (D4 Published development or research report or study )

  
  

• Tutkimuksen eettinen ennakkoarviointi  (2015)  Kliinisen tutkimuksen etiikka - Opas tutkijoille ja eettisille toimikunnille Varis T, Scheinin M, Tuominen JP, Pasternack A
  (D2 Article in a professional compilation book)

  
  

• Validation of [11C]ORM-13070 as a PET tracer for alpha2c-adrenoceptors in the human brain  (2015)  
  • Synapse
   Jussi Lehto, Mika M. Hirvonen, Jarkko Johansson, Jukka Kemppainen, Pauliina Luoto, Tarja Naukkarinen, Vesa Oikonen, Eveliina Arponen, Juha Rouru, Jukka Sallinen, Harry Scheinin, Lauri Vuorilehto, Sjoerd J. Finnema, Christer Halldin, Juha O. Rinne, Mika Scheinin
  (A1 Refereed original research article in a scientific journal)

  
  

• ¹¹C-ORM-13070, a novel PET ligand for brain α₂C-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men.  (2014)  
  • European Journal of Nuclear Medicine and Molecular Imaging
   Luoto P, Suilamo S, Oikonen V, Arponen E, Helin S, Herttuainen J, Hietamäki J, Holopainen A, Kailajärvi M, Peltonen JM, Rouru J, Sallinen J, Scheinin M, Virta J, Virtanen K, Volanen I, Roivainen A, Rinne JO
  (A1 Refereed original research article in a scientific journal)

  
  

• A PET Tracer for Brain α2C Adrenoceptors, 11C-ORM-13070: Radiosynthesis and Preclinical Evaluation in Rats and Knockout Mice  (2014)  
  • Journal of Nuclear Medicine
   Arponen E, Helin S, Marjamäki P, Grönroos T, Holm P, Löyttyniemi E, Någren K, Scheinin M, Haaparanta-Solin M, Sallinen J, Solin O
  (A1 Refereed original research article in a scientific journal)

  
  

• Fluorinated analogues of marsanidine, a highly α2-AR/imidazoline I1 binding site-selective hypotensive agent. Synthesis and biological activities.  (2014)  
  • European Journal of Medicinal Chemistry
   Wasilewska A, Sączewski F, Hudson AL, Ferdousi M, Scheinin M, Laurila JM, Rybczyńska A, Boblewski K, Lehmann A
  (A1 Refereed original research article in a scientific journal)

  
  

• In vivo PET imaging of beta-amyloid deposition in mouse models of Alzheimer's disease with a high specific activity PET imaging agent [18F]flutemetamol  (2014)  
  • EJNMMI Research
   Anniina Snellman, Johanna Rokka, Francisco R López-Picón, Olli Eskola, Mario Salmona, Gianluigi Forloni, Mika Scheinin, Olof Solin, Juha O Rinne, Merja Haaparanta-Solin
  (A1 Refereed original research article in a scientific journal)