MD, PhD, Plastic Surgeon Pauliina Hartiala - UTU Research Portal

Pauliina Hartiala
MD, PhD, Plastic Surgeon

- Docent,
Surgery (Department of Clinical Medicine)
- ,
InFLAMES Flagship (Faculty of Medicine)
- Senior Research Fellow,
MediCity (Faculty of Medicine)

pauliina.hartiala@utu.fi

: https://orcid.org/0000-0002-7606-7813

Expertese: lymphedema; lymphangiogenesis; reconstructive microsurgery

Pathophysiology, prediction and treatment of complications after breast cancer treatment

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Fat Grafting With Lymphedema Fat: From Trash to Treasure? (2025)
- Plastic and Reconstructive Surgery Global Open
Hartiala, Pauliina; Steiner, Aida K.; Niemi, Tarja
HSF2 drives breast cancer progression by acting as a stage-specific switch between proliferation and invasion (2025)
- Science Advances
Pessa, Jenny C.; Paavolainen, Oona; Hästbacka, Hendrik S. E.; Puustinen, Mikael C.; Da Silva, Alejandro J.; Pihlström, Sandra; Gramolelli, Silvia; Boström, Pia; Hartiala, Pauliina; Peuhu, Emilia; Joutsen, Jenny; Sistonen, Lea
Phase II study shows potential benefit of adenoviral vascular endothelial growth factor C (VEGF-C) and lymph node transfer in lymphedema (2025)
- Plastic and Reconstructive Surgery
Rannikko, EH; Pajula, S; Suominen, SH; Kiiski, J; Mani, MR; Halle, M; Kaartinen, IS; Lahdenperä, O; Arnardottir, TH; Kauhanen, SM; Kavola, H; Majava, M; Niemi, TS; Brück, NM; Mäki, MT; Seppänen, MP; Saarikko, AM; Hartiala, P
Tissue-Level Effects of Autologous Fat Grafting in Hypertrophic Scars—A Case Series Study (2025)
- Journal of Surgical Research
Laukka, Mervi; Kauhanen, Susanna; Hockerstedt, Anna; Peuhu, Emilia; Hartiala, Pauliina
Breast cancer related lymphedema-novel regenerative therapies: a narrative review (2024)
- Annals of Breast Surgery
Rannikko Eeva, Visuri Mikko, Hartiala Pauliina
Donor-site safety in microvascular lymph node transfer for breast cancer-related lymphedema using reverse lymphatic mapping—A prospective study (2024)
- Journal of Plastic, Reconstructive and Aesthetic Surgery
Pajula, Susanna; Saarikko, Anne; Suominen, Sinikka; Kaartinen, Ilkka; Kiiski, Juha; Mani, Maria; Halle, Martin; Hartiala, Pauliina
Imunesteturvotuksen hoito (2024) Kirurgia Hartiala, Pauliina
Lymphedema: Experimental Research and Future Directions (2024) Modern surgical management of chronic lymphedema Visuri, Mikko; Saarikko, Anne; Hartiala, Pauliina
Volumetric analysis of the terminal ductal lobular unit architecture and cell phenotypes in the human breast (2024)
- Cell Reports
Paavolainen, Oona; Peurla, Markus; Koskinen, Leena M.; Pohjankukka, Jonna; Saberi, Kamyab; Tammelin, Ella; Sulander, Suvi-Riitta; Valkonen, Masi; Mourao, Larissa; Boström, Pia; Brück, Nina; Ruusuvuori, Pekka; Scheele, Colinda L.G.J.; Hartiala, Pauliina; Peuhu, Emilia
IGFBP2 secretion by mammary adipocytes limits breast cancer invasion (2023)
- Science Advances
Conway James RW, Dinc Defne D, Follain Gautier, Paavolainen Oona, Kaivola Jasmin, Boström Pia, Hartiala Pauliina, Peuhu Emilia, Ivaska Johanna
MYO10-filopodia support basement membranes at pre-invasive tumor boundaries (2022)
- Developmental Cell
Peuhu Emilia, Jacquemet Guillaume, Scheele Colinda LGJ, Isomursu Aleksi, Laisne Marie-Catherine, Koskinen Leena M, Paatero Ilkka, Thol Kerstin, Georgiadou Maria, Guzmán Camilo, Koskinen Satu, Laiho Asta, Elo Laura L, Boström Pia, Hartiala Pauliina, van Rheenen Jacco, Ivaska Johanna
Phase 1 Lymfactin® Study: 24-month Efficacy and Safety Results of Combined Adenoviral VEGF-C and Lymph Node Transfer Treatment for Upper Extremity Lymphedema (2022)
- Journal of Plastic, Reconstructive and Aesthetic Surgery
Leppäpuska Ida-Maria, Hartiala Pauliina, Suominen Sinikka, Suominen Erkki, Kaartinen Ilkka, Mäki Maija, Seppänen Marko, Kiiski Juha, Viitanen Tiina, Lahdenperä Outi, Vuolanto Antti, Alitalo Kari, Saarikko Anne M.
Short duration of upper extremity lymphedema correlates with a favorable cytokine response after lymph node transfer surgery (2022)
- Lymphology
Rannikko Eeva H, Leppäpuska Ida M, Laukka Mervi, Saarikko Anne, Hartiala Pauliina
CC chemokine ligand 2 (CCL2) stimulates aromatase gene expression in mammary adipose tissue (2021)
- FASEB Journal
Martínez-Chacón Gabriela, Yatkin Emrah, Polari Lauri, Dinç Deniz D, Peuhu Emilia, Hartiala Pauliina, Saarinen Niina, Mäkelä Sari
Long-term Results of Microvascular Lymph Node Transfer: Correlation of Preoperative Factors and Operation Outcome (2021)
- Plastic and Reconstructive Surgery Global Open
Rannikko Eeva H, Suominen Sinikka H, Saarikko Anne M, Viitanen Tiina P, Mäki Maija T, Seppänen Marko P, Suominen Erkki A, Hartiala Pauliina
Low TGF-β1 in Wound Exudate Predicts Surgical Site Infection After Axillary Lymph Node Dissection (2021)
- Journal of Surgical Research
Leppäpuska Ida M, Rannikko Eeva H, Laukka Mervi, Peuhu Emilia, Veemaa Raili, Viitanen Tiina, Koskivuo Ilkka, Hartiala Pauliina
Phase 1 LymfactinⓇ Study: Short-term Safety of Combined Adenoviral VEGF-C and Lymph Node Transfer Treatment for Upper Extremity Lymphedema (2020)
- Journal of Plastic, Reconstructive and Aesthetic Surgery
Pauliina Hartiala, Sinikka Suominen, Erkki Suominen, Ilkka Kaartinen, Juha Kiiski, Tiina Viitanen, Kari Alitalo, Anne M. Saarikko
Preperitoneal Fat Grafting Inhibits the Formation of Intra-abdominal Adhesions in Mice (2020)
- Journal of Gastrointestinal Surgery
Mervi Laukka, Erika Hoppela, Jemiina Salo, Pia Rantakari, Tove J. Gronroos, Katri Orte, Kaisa Auvinen, Marko Salmi, Heidi Gerke, Kerstin Thol, Emilia Peuhu, Saila Kauhanen, Pirjo Merilahti, Pauliina Hartiala
Combined Surgical Treatment for Chronic Upper Extremity Lymphedema Patients Simultaneous Lymph Node Transfer and Liposuction (2019)
- Annals of Plastic Surgery
Leppäpuska IM, Suominen E, Viitanen T, Rannikko E, Visuri M, Maki M, Saarikko A, Hartiala P
Fat Grafting Can Induce Browning of White Adipose Tissue (2018)
- Plastic and Reconstructive Surgery Global Open
Hoppela E, Gronroos TJ, Saarikko AM, Tervala TV, Kauhanen S, Nuutila P, Kivinen K, Hartiala P