Olli Tenovuo
MD, PhD, Prof. of Neurotraumatology
Department of Neurosciences ollten@utu.fi ORCID identifier: https://orcid.org/0000-0003-1876-3180 |
traumatic brain injury; rehabilitation; biomarkers; imaging
Pathophysiology, diagnostics, treatment, and prognosis of traumatic brain injury
I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.
The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.
Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.
- Injury profiles, demography and representativeness of patients with TBI attending a regional emergency department (2016)
- Brain Injury
(A1 Refereed original research article in a scientific journal) - Peripheral nervous system involvement in primary burning mouth syndromeresults of a pilot study (2016)
- Oral Diseases
(A1 Refereed original research article in a scientific journal) - Pohjoismainen hoitosuositus avuksi pään vammojen arviointiin (2016)
- Lääkärilehti
(D1 Article in a professional journal) - Prediction of Outcome after Traumatic Brain Injury: Comparison of Disease State Index and IMPACT Calculator (2016)
- Studies in Health Technology and Informatics
(A1 Refereed original research article in a scientific journal) - Reproducibility of Tract-based and Region-of-Interest DTI Analysis of Long Association Tracts (2016)
- Clinical Neuroradiology
(A1 Refereed original research article in a scientific journal) - Scandinavian guidelines for initial management of minor and moderate head trauma in children (2016)
- BMC Medicine
(A1 Refereed original research article in a scientific journal) - The Cholinergic Potential, the Vagus Nerve and Challenges in Treatment of Traumatic Brain Injury (2016)
- Current Pharmaceutical Design
(A1 Refereed original research article in a scientific journal) - The Levels of Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury: Correlations With Clinical and Imaging Findings (2016)
- Neurosurgery
(A1 Refereed original research article in a scientific journal) - Variation in structure and process of care in traumatic brain injury: Provider profiles of European Neurotrauma Centers participating in the CENTER-TBI study (2016)
- PLoS ONE
(A1 Refereed original research article in a scientific journal) - Clinical correlates of retrograde amnesia in mild traumatic brain injury (2015)
- Brain Injury
(A1 Refereed original research article in a scientific journal) - Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): A Prospective Longitudinal Observational Study. (2015)
- Neurosurgery
(A1 Refereed original research article in a scientific journal) - Outcomes from mild and moderate traumatic brain injuries among children and adolescents: A systematic review of studies from 2008-2013 (2015)
- Brain Injury
(A2 Refereed review article in a scientific journal ) - Aivovammojen diagnostiikka on kehittymässä (2014)
- Lääkärilehti
(D1 Article in a professional journal) - Automatic Quantification of CT Images for Traumatic Brain Injury (2014)
- International Symposium on Biomedical Imaging
(A4 Refereed article in a conference publication ) - Blood Metabolic Patterns Correlate With the Severity of Traumatic Brain Injury (2014)
- Neurosurgery
(Other publication) - Consistent and Robust 4D Whole-Brain Segmentation: Application to Traumatic Brain Injury (2014)
- International Symposium on Biomedical Imaging
(A4 Refereed article in a conference publication ) - Diffusion tensor tractography-based analysis of the cingulum: clinical utility and findings in traumatic brain injury with chronic sequels. (2014)
- Neuroradiology
(A1 Refereed original research article in a scientific journal) - Interpretation of magnetic resonance imaging in the chronic phase of traumatic brain injury – What is missed in the original reports? (2014)
- Brain Injury
(A1 Refereed original research article in a scientific journal) - Smoking and outcome of traumatic brain injury (2014)
- Brain Injury
(A1 Refereed original research article in a scientific journal) - Sport concussion assessment tool 2 in a civilian trauma sample with mild traumatic brain injury (2014)
- Journal of Neurotrauma
(A1 Refereed original research article in a scientific journal)