Olli Tenovuo
MD, PhD, Prof. of Neurotraumatology
Department of Neurosciences ollten@utu.fi ORCID identifier: https://orcid.org/0000-0003-1876-3180 |
traumatic brain injury; rehabilitation; biomarkers; imaging
Pathophysiology, diagnostics, treatment, and prognosis of traumatic brain injury
I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.
The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.
Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.
- Early Predictors of Employment Status One Year Post Injury in Individuals with Traumatic Brain Injury in Europe (2020)
- Journal of Clinical Medicine
(A1 Refereed original research article in a scientific journal) - End-of-life practices in traumatic brain injury patients: Report of a questionnaire from the CENTER-TBI study (2020)
- Journal of Critical Care
(A1 Refereed original research article in a scientific journal) - Epidemiological Aspects (2020) Management of Severe Traumatic Brain Injury Majdan Marek, Ingebrigtsen Tor, Tenovuo Olli
(B2 Non-refereed book chapter or chapter in a compilation book) - Evaluation of the relationship between slow-waves of intracranial pressure, mean arterial pressure and brain tissue oxygen in TBI: a CENTER-TBI exploratory analysis. (2020)
- Journal of Clinical Monitoring and Computing
(A1 Refereed original research article in a scientific journal) - Factorial Structure and Validity of Depression (PHQ-9) and Anxiety (GAD-7) Scales after Traumatic Brain Injury (2020)
- Journal of Clinical Medicine
(A1 Refereed original research article in a scientific journal) - Global Characterisation of Coagulopathy in Isolated Traumatic Brain Injury (iTBI): A CENTER-TBI Analysis (2020)
- Neurocritical Care
(A1 Refereed original research article in a scientific journal) - Health-related quality of life after traumatic brain injury: deriving value sets for the QOLIBRI-OS for Italy, The Netherlands and The United Kingdom (2020)
- Quality of Life Research
(A1 Refereed original research article in a scientific journal) - How do 66 European institutional review boards approve one protocol for an international prospective observational study on traumatic brain injury? Experiences from the CENTER-TBI study (2020)
- BMC Medical Ethics
(A2 Refereed review article in a scientific journal ) - Impact of antithrombotic agents on radiological lesion progression in acute traumatic brain injury: A CENTER-TBI propensity-matched cohort analysis (2020)
- Journal of Neurotrauma
(A1 Refereed original research article in a scientific journal) - Impact of duration and magnitude of raised intracranial pressure on outcome after severe traumatic brain injury: A CENTER-TBI high-resolution group study (2020)
- PLoS ONE
(A1 Refereed original research article in a scientific journal)



