Olli Tenovuo
MD, PhD, Prof. of Neurotraumatology
Department of Neurosciences ollten@utu.fi ORCID identifier: https://orcid.org/0000-0003-1876-3180 |
traumatic brain injury; rehabilitation; biomarkers; imaging
Pathophysiology, diagnostics, treatment, and prognosis of traumatic brain injury
I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.
The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.
Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.
- Digital Gaming for Improving the Functioning of People With Traumatic Brain Injury: Randomized Clinical Feasibility Study (2018)
- Journal of Medical Internet Research
(A1 Refereed original research article in a scientific journal) - Emergency department overcrowding: a survey among European neurotrauma centres (2018)
- Emergency Medicine Journal
(B1 Non-refereed article in a scientific journal) - Mortality after traumatic brain injury and the effect of posttraumatic epilepsy (2018)
- Neurology
(A1 Refereed original research article in a scientific journal) - Prehospital Trauma Care among 68 European Neurotrauma Centers: Results of the CENTER-TBI Provider Profiling Questionnaires (2018)
- Journal of Neurotrauma
(A1 Refereed original research article in a scientific journal) - Quantitative EEG parameters for prediction of outcome in severe traumatic brain injury: Development study (2018)
- Clinical EEG and Neuroscience
(A1 Refereed original research article in a scientific journal) - Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury (2018)
- Journal of Neurotrauma
(A1 Refereed original research article in a scientific journal) - Traumatic brain injury: Patient experience and satisfaction with discharge from trauma hospital (2018)
- Journal of Rehabilitation Medicine
(A1 Refereed original research article in a scientific journal) - USABILITY OF WORLD HEALTH ORGANIZATION DISABILITY ASSESSMENT SCHEDULE IN CHRONIC TRAUMATIC BRAIN INJURY (2018)
- Journal of Rehabilitation Medicine
(A1 Refereed original research article in a scientific journal) - Variation in Blood Transfusion and Coagulation Management in Traumatic Brain Injury at the Intensive Care Unit: A Survey in 66 Neurotrauma Centers Participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study (2018)
- Journal of Neurotrauma
(A1 Refereed original research article in a scientific journal) - Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers in participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study (2018)
- Critical Care
(A1 Refereed original research article in a scientific journal) - GFAP and UCH-I1 as predictors of outcome in mild and moderate traumatic brain injury (2017)
- Brain Injury
(Other publication) - Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 Are Not Specific Biomarkers for Mild CT-Negative Traumatic Brain Injury (2017)
- Journal of Neurotrauma
(A1 Refereed original research article in a scientific journal) - Health professionals' perception on the traumatic brain injury care pathways: A SWOT analysis (2017)
- Brain Injury
(Other publication) - High angular resolution diffusion-weighted imaging in mild traumatic brain injury (2017)
- NeuroImage: Clinical
(A1 Refereed original research article in a scientific journal) - Management of mild traumatic brain injury at the emergency department and hospital admission in Europe: A survey of 71 neurotrauma centers participating in the CENTER-TBI study (2017)
- Journal of Neurotrauma
(A1 Refereed original research article in a scientific journal) - Metabolomics profiling as a diagnostic tool in severe traumatic brain injury (2017)
- Frontiers in Neurology
(A2 Refereed review article in a scientific journal ) - Neuroinflammation following traumatic brain injury: A positron emission tomography study (2017)
- Brain Injury
(Other publication) - Pediatric TBI in Finland: An examination of hospital discharges (1998-2012) (2017)
- European Journal of Paediatric Neurology
(A1 Refereed original research article in a scientific journal) - Regional brain morphometry in patients with traumatic brain injury based on acute- and chronic-phase magnetic resonance imaging (2017)
- PLoS ONE
(A1 Refereed original research article in a scientific journal) - Rehabilitation after traumatic brain injury: A survey in 70 European neurotrauma centres participating in the CENTER-TBI study (2017)
- Journal of Rehabilitation Medicine
(A1 Refereed original research article in a scientific journal)



