Olli Tenovuo
 MD, PhD, Prof. of Neurotraumatology

Department of Neurosciences

ollten@utu.fi




ORCID identifierhttps://orcid.org/0000-0003-1876-3180





Areas of expertise
traumatic brain injury; rehabilitation; biomarkers; imaging

Research community or research topic
Pathophysiology, diagnostics, treatment, and prognosis of traumatic brain injury

Biography

I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.



Research

The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.



Teaching

Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.



Publications
  
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  • Structural Brain Connectivity Correlates with Outcome in Mild Traumatic Brain Injury  (2022)  
    • Journal of Neurotrauma
     Roine Timo, Mohammadian Mehrbod, Hirvonen Jussi, Kurki Timo, Posti Jussi P, Takala Riikka SK, Newcombe Virginia F, Tallus Jussi, Katila Ari J, Maanpää Henna-Riikka, Frantzen Janek, Menon David, Tenovuo Olli
    (
    A1 Refereed original research article in a scientific journal)


  • Traumatic brain injury: progress and challenges in prevention, clinical care, and research  (2022)  
    • Lancet Neurology
     Maas Andrew IR, Menon David K, Manley Geoffrey T, Abrams Mathew, Åkerlund Cecilia, Andelic Nada, Aries Marcel, Bashford Tom, Bell Michael J, Bodien Yelena G, Brett Benjamin L, Büki András, Chesnut Randall M, Citerio Giuseppe, Clark David, Clasby Betony, Cooper D Jamie, Czeiter Endre, Czosnyka Marek, Dams-O'Connor Kristen, De Keyser Véronique, Diaz-Arrastia Ramon, Ercole Ari, van Essen Thomas A, Falvey Éanna, Ferguson Adam R, Figaji Anthony, Fitzgerald Melinda, Foreman Brandon, Gantner Dashiell, Gao Guoyi, Giacino Joseph, Gravesteijn Benjamin, Guiza Fabian, Gupta Deepak, Gurnell Mark, Haagsma Juanita A, Hammond Flora M, Hawryluk Gregory, Hutchinson Peter, van der Jagt Mathieu, Jain Sonia, Jain Swati, Jiang Ji-yao, Kent Hope, Kolias Angelos, Kompanje Erwin JO, Lecky Fiona, Lingsma Hester F, Maegele Marc, Majdan Marek, Markowitz Amy, McCrea Michael, Meyfroidt Geert, Mikolić Ana, Mondello Stefania, Mukherjee Pratik, Nelson David, Nelson Lindsay D, Newcombe Virginia, Okonkwo David, Orešič Matej, Peul Wilco, Pisică Dana, Polinder Suzanne, Ponsford Jennie, Puybasset Louis, Raj Rahul, Robba Chiara, Røe Cecilie, Rosand Jonathan, Schueler Peter, Sharp David J, Smielewski Peter, Stein Murray B, von Steinbüchel Nicole, Stewart William, Steyerberg Ewout W, Stocchetti Nino, Temkin Nancy, Tenovuo Olli, Theadom Alice, Thomas Ilias, Espin Abel Torres, Turgeon Alexis F, Unterberg Andreas, Van Praag Dominique, van Veen Ernest, Verheyden Jan, Vande Vyvere Thijs, Wang Kevin KW, Wiegers Eveline JA, Williams W Huw, Wilson Lindsay, Wisniewski Stephen R, Younsi Alexander, Yue John K, Yuh Esther L, Zeiler Frederick A, Zeldovich Marina, Zemek Roger; for the InTBIR Participants and Investigators
    (
    A1 Refereed original research article in a scientific journal)


  • Validation of cross-sectional and longitudinal ComBat harmonization methods for magnetic resonance imaging data on a travelling subject cohort  (2022)  
    • Neuroimage: reports
     Richter Sophie, Winzeck Stefan, Correia Marta M, Kornaropoulos Evgenios N, Manktelow Anne, Outtrim Joanne, Chatfield Doris, Posti Jussi P, Tenovuo Olli, Williams Guy B, Menon David K, Newcombe Virginia FJ
    (
    A1 Refereed original research article in a scientific journal)


  • Acute Kidney Injury in Traumatic Brain Injury Patients: Results From the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study  (2021)  
    • Critical Care Medicine
     Robba Chiara, Banzato Erika, Rebora Paola, Iaquaniello Carolina, Huang Chao-Yuan, Wiegers Eveline JA, Meyfroidt Geert, Citerio Giuseppe; for The Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) ICU Participants and Investigators
    (
    A1 Refereed original research article in a scientific journal)


  • Analysis of Cardio-Cerebral Crosstalk Events in an Adult Cohort from the CENTER-TBI Study  (2021)  Intracranial Pressure and Neuromonitoring XVII Dimitri Giovanna Maria, Beqiri Erta, Czosnyka Marek, Ercole Ari, Smielewski Peter, Lio Pietro; CENTER-TBI High Resolution Substudy Participants and Investigators
    (
    A3 Refereed book chapter or chapter in a compilation book)


  • Assessing the Severity of Traumatic Brain Injury-Time for a Change?  (2021)  
    • Journal of Clinical Medicine
     Tenovuo Olli, Diaz-Arrastia Ramon, Goldstein Lee E, Sharp David J, van der Naalt Joukje, Zasler Nathan D
    (
    A2 Refereed review article in a scientific journal )


  • Association between Physiological Signal Complexity and Outcomes in Moderate and Severe Traumatic Brain Injury: A CENTER-TBI Exploratory Analysis of Multi-Scale Entropy  (2021)  
    • Journal of Neurotrauma
     Zeiler Frederick A, Ercole Ari, Placek Michal M, Hutchinson Peter J, Stocchetti Nino, Czosnyka Marek, Smielewski Peter; CENTER-TBI High-Resolution ICU (HR-ICU) Sub-Study Participants and Investigators
    (
    A1 Refereed original research article in a scientific journal)


  • Biomarkers in Traumatic Brain Injury  (2021)  Traumatic Brain Injury Posti Jussi P, Tenovuo Olli
    (
    B2 Non-refereed book chapter or chapter in a compilation book)


  • Brain Temperature Influences Intracranial Pressure and Cerebral Perfusion Pressure After Traumatic Brain Injury: A CENTER-TBI Study  (2021)  
    • Neurocritical Care
     Birg Tatiana, Ortolano Fabrizio, Wiegers Eveline J.A., Smielewski Peter, Savchenko Yan, Ianosi Bogdan A., Helbok Raimund, Rossi Sandra, Carbonara Marco, Zoerle Tommaso, Stocchetti Nino
    (
    A1 Refereed original research article in a scientific journal)


  • Care transitions in the first 6 months following traumatic brain injury: Lessons from the CENTER-TBI study  (2021)  
    • Annals of physical and rehabilitation medicine
     Borgen Ida MH, Røe Cecilie, Brunborg Cathrine, Tenovuo Olli, Azouvi Philippe, Dawes Helen, Majdan Marek, Ranta Jukka, Rusnak Martin, Wiegers Eveline JA, Tverdal Cathrine, Jacob Louis, Cogné Mélanie, Steinbuechel Nicole V, Andelic Nada, CENTER-TBI participants investigators
    (
    A1 Refereed original research article in a scientific journal)



Last updated on 12/07/2023 12:19:40 PM