Arto Pulliainen
principal investigator, PhD
bacteriology; cell biology; bacterial toxins; protein chemistry; drug development
Principal investigator (2015-, University of Turku, Turku, Finland)
Docent / Adjunct professor (2012-, University of Helsinki, Helsinki, Finland)
Post doc (2006-2014, University of Turku, Turku, Finland and Biozentrum, Basel, Switzerland)
PhD (2006, University of Turku, Turku, Finland)
Doctoral student (2001-2006, University of Turku, Turku, Finland)
MSc (2001, University of Oulu, Oulu, Finland)
Turku Cellular Microbiology Laboratory (TCML) studies the interaction of bacterial pathogens with their host cells at molecular level. Our research is focused on proteins, in particular on enzymes, of the bacterial pathogen and of the host cell that are key molecular players shaping the development and severity of an infectious disease. Our goal is to gain detailed molecular knowledge of the protein functions allowing development of targeted pharmaceuticals to prevent and treat infectious diseases.
Funding sources:
Academy of Finland, Novo Nordisk Foundation, Jane and Aatos Erkko Foundation, Sigrid Jusélius Foundation, Finnish Cultural Foundation, The Finnish Society of Sciences and Letters, Jenny and Antti Wihuri Foundation, Emil Aaltonen Foundation, Turku University Foundation, Turku Doctoral Programme of Molecular Medicine (TuDMM), Erasmus+
bacteriology; cell biology; protein chemistry; molecular biology
- Molecular Evidence of Chlamydia-Like Organisms in the Feces of Myotis daubentonii Bats (2017)
- Applied and Environmental MicrobiologyEmerging Infectious Diseases
- (2015)
- Epidemiology and InfectionProceedings of the National Academy of Sciences of the United States of America
- (2015)
- Vector-Borne and Zoonotic DiseasesFEMS Microbiology Reviews
- Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems (2015)
- mBioJournal of Biological Chemistry
- Bats as reservoir hosts of human bacterial pathogen, Bartonella mayotimonensis (2014)
- Cat Scratch Disease Caused by Bartonella grahamii in an Immunocompromised Patient (2013)
- Journal of Clinical Microbiology
- Bacterial effector binds host cell adenylyl cyclase to potentiate G-alfa-s-dependent cAMP production (2012)
- Persistence of Bartonella spp. stealth pathogens: from subclinical infections to vasoproliferative tumor formation (2012)
- Systemic analysis of gene expression profiles identifies ErbB3 as a potential drug target in pediatric alveolar rhabdomyosarcoma (2012)
- PLoS ONE
- Identification of a Novel Streptococcal Adhesin P (SadP) Protein Recognizing Galactosyl-alpha 1-4-galactose-containing Glycoconjugates CONVERGENT EVOLUTION OF BACTERIAL PATHOGENS TO BINDING OF THE SAME HOST RECEPTOR (2011)
