Terhi Heino
University Lecturer, Adjunct professor (Docent) in Cell Biology
terhi.j.heino@utu.fi +358 29 450 4027 +358 50 476 5988 Kiinamyllynkatu 10 Turku Office: C440 ORCID identifier: https://orcid.org/0000-0003-2274-6834 |
biomedicine; regenerative medicine; bone tissue; cell biology; stem cells; osteoporosis; fracture healing; osteogenesis; bone growth; angiogenesis; endothelial cells; wound healing; biomaterials
Terhi Heino is a University Lecturer in the Institute of Biomedicine, Faculty of Medicine, at the University of Turku. In this role, she combines teaching with active research and contributes to curriculum development in medical education. Her scientific interests span stem cells, bone and vascular biology, biomaterials, and translational approaches in regenerative medicine.
She earned her PhD in Cell Biology from the University of Turku in 2005. Following post‑doctoral training at the Pediatric Endocrinology Unit of the Department of Women and Child Health at Karolinska Institutet in Sweden, she returned to the University of Turku in 2008. She was awarded the title of Docent (Adjunct Professor) in Cell Biology in 2013.
Her research focuses on understanding the role of various cell types, including mesenchymal stromal cells (MSCs) in bone and vascular biology. The group is particularly interested in cell–cell and cell–biomaterial interactions and their potential applications in regenerative medicine.
The work relies primarily on in vitro cultures of human bone marrow-derived primary MSCs and peripheral blood–derived cells, complemented by cell lines, various biomaterials, and clinically relevant patient samples.
Overall, the research provides new insights into cellular interactions and key molecular mechanisms regulating angiogenesis and osteogenesis, contributing to the development of improved regenerative approaches for bone and soft tissue healing.
Terhi Heino has extensive experience in university‑level teaching, with over two decades of work in both undergraduate and postgraduate education. Her teaching focuses on histology, cell biology, anatomy, pharmacology, regenerative medicine, and cancer biology. She contributes actively to curriculum planning, implementation, and pedagogical development, supported by her formal pedagogic qualification (60 ECTS, University of Turku). She has served as a mentor in the Biomedicine BSc programme (2013–2022) and has international teaching experience through the Molecular Medicine course at Karolinska Institutet (2013–2018). In addition, she has worked as a partner and mentor in an EU‑funded multidisciplinary entrepreneurial education project (IDEATE, 2013–2016).
- Effects of γ-MPS silanization on the physicochemical and biological properties of bioactive glass S53P4 (2026)
- Dental Materials
(A1 Refereed original research article in a scientific journal) - Female mice with HSD17B1 inactivation show mild hyperandrogenism without notable impact on reproductive function or bone (2026)
- Endocrinology
(A1 Refereed original research article in a scientific journal) - Endocrine Functions of Bone Are Suppressed by Orally Administered Glucose Regardless of Bodyweight (2025)
- Clinical Endocrinology
(A1 Refereed original research article in a scientific journal) - Exploring the Reactions Induced by Bioactive Glass Air Abrasion of Titanium and Their Effects on Osteoblast Cellular Responses (2025)
- Journal of Biomedical Materials Research Part A
(A1 Refereed original research article in a scientific journal) - Unraveling the immunomodulatory and metabolic effects of bioactive glass S53P4 on macrophages in vitro (2025)
- Journal of Materials Science: Materials in Medicine
(A1 Refereed original research article in a scientific journal) - A perspective on muscle phenotyping in musculoskeletal research (2024)
- Trends in Endocrinology and Metabolism
(A2 Refereed review article in a scientific journal ) - Short- and long-term exposure to high glucose induces unique transcriptional changes in osteoblasts in vitro (2024)
- Biology Open
(A1 Refereed original research article in a scientific journal) - The complex role of Rcor2 : Regulates mesenchymal stromal cell differentiation in vitro but is dispensable in vivo (2024)
- BONE
(A1 Refereed original research article in a scientific journal) - Tribological behavior and biocompatibility of novel Nickel-Free stainless steel manufactured via laser powder bed fusion for biomedical applications (2024)
- Materials and Design
(A1 Refereed original research article in a scientific journal) - Bioactive glasses promote rapid pre-osteoblastic cell migration in contrast to hydroxyapatite, while carbonated apatite shows migration inhibiting properties (2023)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Physicochemical and biological characterization of functionalized calcium carbonate (2023)
- Materialia
(A1 Refereed original research article in a scientific journal) - Evidence for the in vivo existence and mobilization of myeloid angiogenic cells and pericyte-like cells in wound patients after skin grafting (2022)
- Wound Repair and Regeneration
(A1 Refereed original research article in a scientific journal) - Mesenchymal cell-derived Wnt1 signaling regulates subchondral bone remodeling but has no effects on the development of growth plate or articular cartilage in mice (2022)
- BONE
(A1 Refereed original research article in a scientific journal) - Physicochemical and biological characterization of silica-coated alumina particles (2022)
- Dental Materials
(A1 Refereed original research article in a scientific journal) - Signature of circulating small non-coding RNAs during early fracture healing in mice (2022)
- Bone Reports
(A1 Refereed original research article in a scientific journal) - Tuki- ja liikuntaelimistön kudosten rakenne ja toiminta (2022) Ortopedia Säämänen Anna-Marja, Heino Terhi, Arokoski Jari, Järvinen Tero, Korhonen Rami
(D2 Article in a professional compilation book) - An In Vitro Co-Culture Model of Bone Marrow Mesenchymal Stromal Cells and Peripheral Blood Mononuclear Cells Promotes the Differentiation of Myeloid Angiogenic Cells and Pericyte-Like Cells (2021)
- Stem Cells and Development
(A1 Refereed original research article in a scientific journal) - Multiple targets identified with genome wide profiling of small RNA and mRNA expression are linked to fracture healing in mice (2021)
- Bone Reports
(A1 Refereed original research article in a scientific journal) - Osteoblastic Wnt1 regulates periosteal bone formation in adult mice (2021)
- BONE
(A1 Refereed original research article in a scientific journal) - Structural and elemental characterization of glass and ceramic particles for bone surgery (2021)
- Dental Materials
(A1 Refereed original research article in a scientific journal)



