Jaana Vuopio
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology
jaana.vuopio@utu.fi Kiinamyllynkatu 10 Turku Työhuone: 7th floor, room 7024 ORCID-tunniste: https://orcid.org/https://orcid.org/0000-0002-0795-4822 |
• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci, genomic evolution of the bacterium, host susceptibility and risk factors to these infections.
• Molecular epidemiology, surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens
Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.
Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.
Our current research areas cover:
- Invasive Group A streptococcal disease
- Molecular epidemiology and disease burden of Group A streptococcal infections
- Molecular epidemiology and spread of MRSA
- Surveillance of AMR
Research group members:
- Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
- Johanna Vilhonen, M.D., Ph.D., specialist in IDs
- Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
- Jaakko Silvola, M.D., Ph.D. fellow
- Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
- Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
- Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)
- Molecular epidemiology of Staphylococcus epidermidis isolates in a hematological unit during a 4-month survey (1995)
- Scandinavian Journal of Infectious Diseases
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Neonatal Candida parapsilosis outbreak with a high case fatality rate (1995)
- Pediatric Infectious Disease Journal
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Outbreak caused by two multi-resistant Acinetobacter baumannii clones in a burns unit: emergence of resistance to imipenem (1995)
- Journal of Hospital Infection
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Persistence of a multiresistant clone of Staphylococcus epidermidis in a neonatal intensive-care unit for a four-year period (1995)
- Clinical Infectious Diseases
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Testing of methicillin resistance by in vitro susceptibility and the presence of the mecA gene in clinical Staphylococcus aureus isolates in Finland (1995)
- Scandinavian Journal of Infectious Diseases
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Evaluation of methods for epidemiologic typing of group A streptococci (1994)
- Journal of Infectious Diseases
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Rapid detection of methicillin-resistant Staphylococcus aureus strains not identified by slide agglutination tests (1994)
- Journal of Clinical Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - The in-vitro susceptibilities of toxigenic strains of Corynebacterium diphtheriae isolated in northwestern Russia and surrounding areas to ten antibiotics (1994)
- Journal of Antimicrobial Chemotherapy
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Cloning and characterization of the bundle-forming pilin gene of enteropathogenic Escherichia coli and its distribution in Salmonella serotypes (1993)
- Molecular Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Detection of enterobacterial lipopolysaccharides and experimental endotoxemia by means of an immunolimulus assay using both serotype-specific and cross-reactive antibodies (1993)
- Journal of Infectious Diseases
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Diphtheria and travel (1993)
- Lancet
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Localized adherence by enteropathogenic Escherichia coli is an inducible phenotype associated with the expression of new outer membrane proteins (1991)
- Journal of Experimental Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - A strong antibody response to the periplasmic C-terminal domain of the OmpA protein of Escherichia coli is produced by immunization with purified OmpA or with whole E coli or Salmonella typhimurium bacteria (1990)
- Infection and Immunity
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Effect of polyinosinic-polycytidylic acid (pl:C) on experimental mouse salmonellosis (1990)
- Microbial Pathogenesis
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Experimental Escherichia coli peritonitis in immunosuppressed mice: the role of specific and non-specific immunity (1988)
- Journal of Medical Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Killing of Escherichia coli in the peritoneal cavity of convalescent mice; role of specific and non-specific immune mechanisms (1988)
- Journal of Medical Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Lipopolysaccharide-induced non-specific resistance to systemic Escherichia coli infection in mice (1988)
- Journal of Medical Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Protective capacity of antibodies to outer-membrane components of Escherichia coli in a systemic mouse peritonitis model (1988)
- Journal of Medical Microbiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Fimbrial phase variation and systemic E coli infection studied in the mouse peritonitis model (1986)
- Microbial Pathogenesis
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )