Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology Jaana Vuopio - UTU Research Portal

Jaana Vuopio
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology

- Senior Advisor,
Institute of Biomedicine (Faculty of Medicine)

jaana.vuopio@utu.fi

Kiinamyllynkatu 10

Turku

: 7th floor, room 7024

: https://orcid.org/https://orcid.org/0000-0002-0795-4822

• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci, genomic evolution of the bacterium, host susceptibility and risk factors to these infections.
• Molecular epidemiology, surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens

Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.

Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.

Our current research areas cover:

Invasive Group A streptococcal disease
Molecular epidemiology and disease burden of Group A streptococcal infections
Molecular epidemiology and spread of MRSA
Surveillance of AMR

Research group members:

Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
Johanna Vilhonen, M.D., Ph.D., specialist in IDs
Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
Jaakko Silvola, M.D., Ph.D. fellow
Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)

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Factors predisposing to acute and recurrent bacterial non-necrotizing cellulitis in hospitalized patients: a prospective case-control study (2010)
- Clinical Microbiology and InfectionEmerging Infectious Diseases
Karppelin M, Siljander T, Vuopio-Varkila J, Kere J, Huhtala H, Vuento R, Jussila T, Syrjänen J
Human cases of methicillin-resistant Staphylococcus aureus CC398, Finland (2010)
- Emerging Infectious Diseases
Salmenlinna S, Lyytikäinen O, Vainio A, Myllyniemi AL, Raulo S, Kanerva M, Rantala M, Thomson K, Seppänen J, Vuopio J
Streptococcus dysgalactiae subsp equisimilis Bacteremia, Finland, 1995-2004. (2010)
- Emerging Infectious Diseases
Rantala S, Vahakuopus S, Vuopio-Varkila J, Vuento R, Syrjanen J
[Update on current care guidelines Bacterial skin infections]. (2010)
- Duodecim
Ranki A, Hyry H, Klimenko T, Laukkala T, Majamaa H, Mäkelä M, Syrjänen J, Vuopio J, Vuopio J, Vuopio J, Vuopio J
Carriage of methicillin-resistant Staphylococci and their SCCmec types in a long-term-care facility2009
- Journal of Clinical MicrobiologyClinical Infectious Diseases
Ibrahem S, Salmenlinna S, Virolainen A, Kerttula AM, Lyytikäinen O, Jägerroos H, Broas M, Vuopio-Varkila J
Clinical and microbiological characteristics of severe Streptococcus pyogenes disease in EuropeBinding of complement regulators factor H and C4b binding protein to group A streptococcal strains isolated from tonsillar tissue and blood (2009)
- Journal of Clinical MicrobiologyMicrobes and Infection
Luca-Harari B, Darenberg J, Neal S, Siljander T, Strakova L, Tanna A, Creti R, Ekelund K, Koliou M, Tassios PT, van der Linden M, Straut M, Vuopio-Varkila J, Bouvet A, Efstratiou A, Henriques-Normark B, Schalén C, Jasir A, Henriques-Normark B
Clinical presentations and epidemiology of beta-haemolytic streptococcal bacteraemia: a population-based studyClonality of epidemic methicillin-resistant Staphylococcus aureus strains in Finland as defined by several molecular methods (2009)
- Clinical Microbiology and InfectionEuropean Journal of Clinical Microbiology and Infectious Diseases
Rantala S, Vuopio-Varkila J, Vuento R, Huhtala H, Syrjänen J
(2009)
- Journal of Clinical MicrobiologyMolecular Microbiology
Kanerva M, Salmenlinna S, Vuopio-Varkila J, Lehtinen P, Möttönen T, Virtanen MJ, Lyytikäinen O
(2009)
- European Journal of Clinical Microbiology and Infectious DiseasesEurosurveillance
Sissonen S, Pasanen T, Salmenlinna S, Vuopio-Varkila J, Tarkka E, Vaara M, Tissari P
Methicillin-Resistant Staphylococcus aureus Screening by Online Immunometric Monitoring of Bacterial Growth under Selective Pressure (2009)
- Antimicrobial Agents and Chemotherapy
Stenholm T, Hakanen AJ, Vaarno J, Pihlasalo S, Terho P, Hanninen PE, Vuopio-Varkila J, Huovinen P, Kotilainen P
Predictors of death after severe Streptococcus pyogenes infection (2009)
Lamagni TL, Neal S, Keshishian C, Powell D, Potz N, Pebody R, George R, Duckworth G, Vuopio-Varkila J, Efstratiou A
Predictors of mortality in beta-hemolytic streptococcal bacteremia: a population-based study (2009)
- Journal of Infection
Rantala S, Vuopio-Varkila J, Vuento R, Huhtala H, Syrjänen J
Rapid emergence of emm84 among invasive Streptococcus pyogenes infections in Finland (2009)
- Journal of Clinical Microbiology
Siljander T, Lyytikäinen O, Vähäkuopus S, Säilä P, Jalava J, Vuopio-Varkila J
Acute bacterial, nonnecrotizing cellulitis in Finland: microbiological findings (2008)
Siljander T, Karppelin M, Vähäkuopus S, Syrjänen J, Toropainen M, Kere J, Vuento R, Jussila T, Vuopio-Varkila J
(2008)
Suvilehto J, Jarva H, Seppänen M, Siljander T, Vuopio-Varkila J, Meri S
(2008)
Vainio A, Kardén-Lilja M, Ibrahem S, Kerttula AM, Salmenlinna S, Virolainen A, Vuopio-Varkila J
Complement factor H allotype 402H is associated with increased C3b opsonization and phagocytosis of Streptococcus pyogenes (2008)
Haapasalo K, Jarva H, Siljander T, Tewodros W, Vuopio-Varkila J, Jokiranta TS
Emergence and spread of vancomycin resistance among enterococci in Europe (2008)
Werner G, Coque TM, Hammerum AM, Hope R, Hryniewicz W, Johnson A, Klare I, Kristinsson KG, Leclercq R, Lester CH, Lillie M, Novais C, Olsson-Liljequist B, Peixe LV, Sadowy E, Top J, Simonsen GS, Willems RJ, Vuopio-Varkila J, Woodford N, Witte W
Epidemic of severe Streptococcus pyogenes infections in injecting drug users in the UK, 2003-2004. (2008)
- Clinical Microbiology and Infection
Lamagni TL, Neal S, Keshishian C, Hope V, George R, Duckworth G, Vuopio-Varkila J, Efstratiou A
Epidemiology of severe Streptococcus pyogenes disease in Europe (2008)
- Journal of Clinical Microbiology
Lamagni TL, Darenberg J, Luca-Harari B, Siljander T, Efstratiou A, Henriques-Normark B, Vuopio-Varkila J, Bouvet A, Creti R, Ekelund K, Koliou M, Reinert RR, Stathi A, Strakova L, Ungureanu V, Schalén C, Schalén C, Jasir A