Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology Jaana Vuopio - UTU Research Portal

Jaana Vuopio
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology

- Senior Advisor,
Institute of Biomedicine (Faculty of Medicine)

jaana.vuopio@utu.fi

Kiinamyllynkatu 10

Turku

: 7th floor, room 7024

: https://orcid.org/https://orcid.org/0000-0002-0795-4822

• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci, genomic evolution of the bacterium, host susceptibility and risk factors to these infections.
• Molecular epidemiology, surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens

Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.

Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.

Our current research areas cover:

Invasive Group A streptococcal disease
Molecular epidemiology and disease burden of Group A streptococcal infections
Molecular epidemiology and spread of MRSA
Surveillance of AMR

Research group members:

Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
Johanna Vilhonen, M.D., Ph.D., specialist in IDs
Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
Jaakko Silvola, M.D., Ph.D. fellow
Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)

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The dynamic changes of dominant clones of Staphylococcus aureus causing bloodstream infections in the European region: Results of a second structured survey (2014)
- Eurosurveillance
H Grundmann, L M Schouls2 , D M Aanensen, G N Pluister, A Tami, M Chlebowicz, C Glasner, A J Sabat, K Weist, O Heuer, A W Friedrich; on behalf of the ESCMID Study Group on Molecular Epidemiological Markers and the European Staphylococcal Reference Laboratory Working Group
Genetic susceptibility to non-necrotizing erysipelas/cellulitis (2013)
- PLoS ONE
Hannula-Jouppi K, Massinen S, Siljander T, Mäkelä S, Kivinen K, Leinonen R, Jiao H, Aitos P, Karppelin M, Vuopio J, Syrjänen J, Kere J
Methicillin-resistant Staphylococcus aureus epidemic restricted to one health district in Finland: a population-based descriptive study in Pirkanmaa, Finland, years 2001-2011. (2013)
- Scandinavian Journal of Infectious Diseases
Laine J, Huttunen R, Vuento R, Arvola P, Levola R, Vuorihuhta M, Syrjänen J, Vuopio J, Lumio J
Molecular typing of vancomycin-resistant Enterococcus faecium with an automated repetitive sequence-based PCR microbial typing system compared with pulsed-field gel electrophoresis and multilocus sequence typing. (2013)
- Scandinavian Journal of Infectious Diseases
Kardén-Lilja M, Vuopio J, Koskela M, Tissari P, Salmenlinna S
Recurrent cellulitis with benzathine penicillin prophylaxis is associated with diabetes and psoriasis. (2013)
- European Journal of Clinical Microbiology and Infectious Diseases
Karppelin M, Siljander T, Huhtala H, Aromaa A, Vuopio J, Hannula-Jouppi K, Kere J, Syrjänen J
Terveysturismissa piilee näkymätön uhka (2013)
- Helsingin Sanomat
Huovinen P, Vuopio J
Acquisition of complement factor H is important for pathogenesis of Streptococcus pyogenes infections: evidence from bacterial in vitro survival and human genetic association. (2012)
- Journal of Immunology
Haapasalo K, Vuopio J, Syrjänen J, Suvilehto J, Massinen S, Karppelin M, Järvelä I, Meri S, Kere J, Jokiranta TS
Distribution of emm types in invasive and non-invasive group A and G streptococci (2012)
- European Journal of Clinical Microbiology and Infectious Diseases
Vähäkuopus Susanna, Vuento Risto, Siljander Tuula, Syrjänen Jaana, Vuopio Jaana
Outbreak analysis and typing of MRSA isolates by automated repetitive-sequence-based PCR in a region with multiple strain types causing epidemics. (2012)
- European Journal of Clinical Microbiology and Infectious Diseases
Hirvonen JJ, Pasanen T, Tissari P, Salmenlinna S, Vuopio J, Kaukoranta SS
Streptococcus pyogenes bacteraemia, emm types and superantigen profiles. (2012)
- European Journal of Clinical Microbiology and Infectious Diseases
Rantala S, Vähäkuopus S, Siljander T, Vuopio J, Huhtala H, Vuento R, Syrjänen J
Adapting spa typing for national laboratory-based surveillance of methicillin-resistant Staphylococcus aureus (2011)
- European Journal of Clinical Microbiology and Infectious Diseases
Vainio A, Koskela S, Virolainen A, Vuopio J, Salmenlinna S
Evaluation of the TPX MRSA assay for the detection of methicillin-resistant Staphylococcus aureus (2011)
- European Journal of Clinical Microbiology and Infectious Diseases
Stenholm T, Hakanen A, Salmenlinna S, Pihlasalo S, Härmä H, Hänninen P, Huovinen P, Vuopio J, Kotilainen P
Livestock-associated methicillin-resistant Staphylococcus aureus in humans, Europe (2011)
- Emerging Infectious Diseases
van Cleef BA, Monnet DL, Voss A, Krziwanek K, Allerberger F, Struelens M, Zemlickova H, Skov RL, Vuopio-Varkila J, Cuny C, Friedrich AW, Spiliopoulou I, Pászti J, Hardardottir H, Rossney A, Pantosti A, Pan A, Grundmann H, Borg M, Olsson-Liljequist B, Mueller-Premru M, Harbarth S, Widmer A, Unal S, Schweiger A, Kluytmans JA
Screening for Corynebacterium diphtheriae and Corynebacterium ulcerans in patients with upper respiratory tract infections 2007-2008: a multicentre European study (2011)
- Clinical Microbiology and Infection
Wagner KS, White JM, Neal S, Crowcroft NS, Kuprevičiene N, Paberza R, Lucenko I, Jõks U, Akbaş E, Alexandrou-Athanassoulis H, Detcheva A, Vuopio J, von Hunolstein C, Murphy PG, Andrews N, Efstratiou A, Andrews N
A selective broth enrichment combined with real-time nuc-mecA-PCR in the exclusion of MRSA (2010)
- APMIS
Pasanen T, Korkeila M, Mero S, Tarkka E, Piiparinen H, Vuopio-Varkila J, Vaara M, Tissari P
Emergence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae during the years 2000 and 2004 in Helsinki, Finland (2010)
- Clinical Microbiology and Infection
Forssten SD, Kolho E, Lauhio A, Lehtola L, Mero S, Oksaharju A, Jalava J, Tarkka E, Vaara M, Vuopio-Varkila J
Epidemiology, outcome and emm types of invasive group A streptococcal infections in Finland (2010)
- European Journal of Clinical Microbiology and Infectious Diseases
Siljander T, Lyytikäinen O, Vähäkuopus S, Snellman M, Jalava J, Vuopio J
Factors predisposing to acute and recurrent bacterial non-necrotizing cellulitis in hospitalized patients: a prospective case-control study (2010)
- Clinical Microbiology and Infection
Karppelin M, Siljander T, Vuopio-Varkila J, Kere J, Huhtala H, Vuento R, Jussila T, Syrjänen J
Human cases of methicillin-resistant Staphylococcus aureus CC398, Finland (2010)
- Emerging Infectious Diseases
Salmenlinna S, Lyytikäinen O, Vainio A, Myllyniemi AL, Raulo S, Kanerva M, Rantala M, Thomson K, Seppänen J, Vuopio J
Streptococcus dysgalactiae subsp equisimilis Bacteremia, Finland, 1995-2004. (2010)
- Emerging Infectious Diseases
Rantala S, Vahakuopus S, Vuopio-Varkila J, Vuento R, Syrjanen J