Katja Kaipio - UTU Research Portal

Katja Kaipio

- Docent,
Institute of Biomedicine (Faculty of Medicine)

kaanka@utu.fi

+358 29 450 4614

+358 50 476 5793

Kiinamyllynkatu 10

Turku

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A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids (2023)
- Developmental Cell
Senkowski Wojciech., Gall-Mas Laura, Falco Matias Marin, Li Yilin, Lavikka Kari, Kriegbaum Mette C., Oikkonen Jaana, Bulanova Daria, Pietras Elin J., Voßgröne Karolin, Chen Yan Jun., Erkan Erdogan Pekcan, Dai Jun, Lundgren Anastasia, Grønning Høg Mia Kristine, Larsen Ida Marie, Lamminen Tarja, Kaipio Katja, Huvila Jutta, Virtanen Anni, Engelholm Lars, Christiansen Pernille, Santoni-Rugiu Eric, Huhtinen Kaisa, Carpén Olli, Hynninen Johanna, Hautaniemi Sampsa, Vähärautio Anna, Wennerberg Krister
A Subset of Secreted Proteins in Ascites Can Predict Platinum-Free Interval in Ovarian Cancer (2022)
- Cancers
Carroll Molly J, Kaipio Katja, Hynninen Johanna, Carpen Olli, Hautaniemi Sampsa, Page David, Kreeger Pamela K
Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status (2022)
- Frontiers in Oncology
Roering Pia, Siddiqui Arafat, Heuser Vanina D, Potdar Swapnil, Mikkonen Pia, Oikkonen Jaana, Li Yilin, Pikkusaari Sanna, Wennerberg Krister, Hynninen Johanna, Grenman Seija, Huhtinen Kaisa, Auranen Annika, Carpén Olli, Kaipio Katja
Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer (2022)
- Science Advances
Zhang Kaiyang, Erkan Erdogan Pekcan, Jamalzadeh Sanaz, Dai Jun, Andersson Noora, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Carpén Olli, Hietanen Sakari, Oikkonen Jaana, Hynninen Johanna, Virtanen Anni, Häkkinen Antti, Hautaniemi Sampsa, Vähärautio Anna
Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype (2022)
- Molecular Cancer Therapeutics
Cvrljevic Anna N., Butt Umar, Huhtinen Kaisa, Grönroos Tove J., Böckelman Camilla, Lassus Heini, Butzow Ralf, Haglund Caj, Kaipio Katja, Arsiola Tiina, Laajala Teemu D., Connolly Denise C, Ristimäki Ari, Carpen Olli, Pouwels Jeroen, Westermarck Jukka
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance (2021)
- Nature Communications
Pietilä Elina A., Gonzalez-Molina Jordi, Moyano-Galceran Lidia, Jamalzadeh Sanaz, Zhang Kaiyang, Lehtinen Laura, Turunen S. Pauliina, Martins Tomás A., Gultekin Okan, Lamminen Tarja, Kaipio Katja, Joneborg Ulrika, Hynninen Johanna, Hietanen Sakari, Grénman Seija, Lehtonen Rainer, Hautaniemi Sampsa, Carpén Olli, Carlson Joseph W., Lehti Kaisa
PRISM: Recovering cell type specific expression profiles from individual composite RNA-seq samples (2021)
- Bioinformatics
Häkkinen Antti, Zhang Kaiyang, Alkodsi Amjad, Andersson Noora, Pekcan Erkan Erdogan, Dai Jun, Kaipio Katja, Lamminen Tarja, Mansuri Naziha, Huhtinen Kaisa, Vähärautio Anna, Carpén Olli, Hynninen Johanna, Hietanen Sakari, Lehtonen Rainer, Hautaniemi Sampsa
Targeting DNA Homologous Repair Proficiency With Concomitant Topoisomerase II and c-Abl Inhibition (2021)
- Frontiers in Oncology
Siddiqui Arafat, Tumiati Manuela, Joko Alia, Sandholm Jouko, Roering, Aakko Pia Sofia, Vainionpää Reetta, Kaipio Katja, Huhtinen Kaisa, Kauppi Liisa, Tuomela Johanna, Hietanen Sakari
ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors (2020)
- Journal of Pathology
Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi, Olli Carpén
Analysis of single-cell RNA-seq data from ovarian cancer samples before and after chemotherapy links stress-related transcriptional profile with chemotherapy resistance (2020)
- bioRxiv
Zhang K, Erkan EP, Dai J, Andersson N, Kaipio K, Lamminen T, Mansuri N, Huhtinen K, Carpen O, Hynninen J, others
Melanocortin 3 receptor activation with [D-Trp8]-γ-MSH suppresses inflammation in apolipoprotein E deficient mice (2020)
- European Journal of Pharmacology
James J.Kadiri, Keshav Thapa, Katja Kaipio, Minying Caid, Victor J. Hruby, Petteri Rinne
qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets (2020)
- Bioinformatics
Häkkinen A, Koiranen J, Casado J, Kaipio K, Lehtonen O, Petrucci E, Hynninen J, Hietanen S, Carpén O, Pasquini L, Biffoni M, Lehtonen R, Hautaniemi S
Singling out tumor heterogeneity and chemoresistance in high-grade serous ovarian cancer (2020)
- Clinical Cancer Research
Erkan EP, Dai J, Zhang KY, Kaipio K, Lamminen T, Mansuri N, Suominen L, Alkodsi A, Huhtinen K, Hietanen S, Hynninen J, Grenman S, Carpen O, Hautaniemi S, Vaharautio A
A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients (2018)
- Clinical Cancer Research
Tumiati M, Hietanen S, Hynninen J, Pietilä E, Färkkilä A, Kaipio K, Roering P, Huhtinen K, Alkodsi A, Li Y, Lehtonen R, Erkan EP, Tuominen MM, Lehti K, Hautaniemi SK, Grénman S, Vähärautio A, Carpén O, Kauppi L
Chemical biology approach to phenotypic intratumor heterogeneity as a source of chemotherapy resistance in high-grade serous ovarian cancer (2018)
- Clinical Cancer Research
Bulanova DR, Kaipio K, Lamminen T, Ianevski A, Aittokallio T, Carpen O, Wennerberg K
Drug sensitivity and resistance testing (DSRT) of clinically important compounds on primary ovarian cancer cell lines. (2018)
- Clinical Cancer Research
Roering P, Mikkonen P, Potdar S, Wennerberg K, Hynninen J, Grenman S, Auranen A, Carpen O, Kaipio K
High-throughput screening of new potential targets for high-grade serous ovarian cancer treatment (2018)
- Clinical Cancer Research
Dai J, Erkan EP, Zhang KY, Kaipio K, Lamminen T, Huhtinen K, Hynninen J, Grenman S, Carpen OM, Hautaniemi S, Vaharautio A
Identifying differentially methylated sites in samples with varying tumor purity (2018)
- Bioinformatics
Antti Häkkinen, Amjad Alkodsi, Chiara Facciotto, Kaiyang Zhang, Katja Kaipio, Sirpa Leppä, Olli Carpén, Seija Grénman, Johanna Hynninen, Sakari Hietanen Rainer Lehtonen, Sampsa Hautaniemi
FHOD1 formin is upregulated in melanomas and modifies proliferation and tumor growth (2017)
- Experimental Cell Research
Peippo Minna, Gardberg Maria, Lamminen Tarja, Kaipio Katja, Carpen Olli, Heuser Vanina D.
Hyper-phosphorylation of Sequestosome-1 Distinguishes Resistance to Cisplatin in Patient Derived High Grade Serous Ovarian Cancer Cells (2017)
- Molecular and Cellular Proteomics
Nguyen Elizabeth V, Huhtinen Kaisa, Goo Young Ah, Kaipio Katja, Andersson Noora, Rantanen Ville, Hynninen Johanna, Lahesmaa Riitta, Carpen Olli, Goodlett David R