A1 Journal article – refereed
Aberrant mesolimbic dopamine-opiate interaction in obesity




List of Authors: Tuominen L, Tuulari J, Karlsson H, Hirvonen J, Helin S, Salminen P, Parkkola R, Hietala J, Nuutila P, Nummenmaa L
Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE
Publication year: 2015
Journal: NeuroImage
Journal name in source: NEUROIMAGE
Journal acronym: NEUROIMAGE
Volume number: 122
Number of pages: 7
ISSN: 1053-8119

Abstract


The study demonstrates a link between DRD2 and MOR availabilities in living human brain. This interaction is selectively disrupted in mesolimbic dopamine system in morbid obesity. We propose that interaction between the dopamine and opioid systems is a prerequisite for normal reward processing and that disrupted cross-talk may underlie altered reward processing in obesity. (C) 2015 Elsevier Inc. All rights reserved.


Last updated on 2019-20-07 at 15:49

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