Refereed journal article or data article (A1)
Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance
List of Authors: Hirvonen J, Virtanen KA, Nummenmaa L, Hannukainen JC, Honka MJ, Bucci M, Nesterov SV, Parkkola R, Rinne J, Iozzo P, Nuutila P
Publisher: AMER DIABETES ASSOC
Publication year: 2011
Journal: Diabetes
Journal name in source: DIABETES
Journal acronym: DIABETES
Number in series: 2
Volume number: 60
Issue number: 2
Start page: 443
End page: 447
Number of pages: 5
ISSN: 0012-1797
DOI: http://dx.doi.org/10.2337/db10-0940
CONCLUSIONS-We found that insulin stimulates brain glucose metabolism at physiological postprandial levels in patients with impaired glucose tolerance but not in healthy subjects. These results suggest that insulin stimulation of brain glucose metabolism is maximal at fasting concentrations in healthy subjects but not in patients with impaired glucose tolerance. Diabetes 60:443-447, 2011