A2 Review article in a scientific journal
HOW DOES ENVIRONMENTAL-POLLUTION AFFECT RED-CELL FUNCTION IN FISH




List of Authors: NIKINMAA M
Publisher: ELSEVIER SCIENCE BV
Publication year: 1992
Journal: Aquatic Toxicology
Journal name in source: AQUATIC TOXICOLOGY
Journal acronym: AQUAT TOXICOL
Volume number: 22
Issue number: 4
Number of pages: 12
ISSN: 0166-445X

Abstract


The present article reviews the effects of environmental pollution on ion transport, metabolism and shape of teleost red cells. Catecholamines liberated into the blood stream in acute stresses activate sodium/proton exchange across thc red cell membrane causing red cell swelling. The exchanger is inhibited by alkyltin compounds and by methaemoglobinaemia. Amphiphiles increase the potassium permeability of the red cell membrane. Exposure to lead inhibits and exposure to tetrachloro-1,2-benzoquinone activates red cell delta-aminolevulinic acid dehydratase. Resin acids, cadmium, lead and oxidizing agents such as monochloramine induce the appearance of abnormal cell shapes. In addition, environmental contamination is often accompanied by an increased frequency of micronuclei in the red cells. Specifically, this effect has been observed during exposure to benzo(a)pyrene. These, and other, examples show that many red cell parameters respond to environmental pollution. Thus, determinations of red cell ion concentrations, microscopic examination of red cells and assays of red cell enzyme activities could be a useful addition to conventional pollution monitoring studies.




Internal Authors/Editors

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