Refereed journal article or data article (A1)

Bacterial antigens in synovial biopsy specimens in yersinia triggered reactive arthritis




List of AuthorsMerilahti-Palo R, Söderström KO, Lahesmaa-Rantala R, Granfors K, Toivanen A

Publication year1991

JournalAnnals of the Rheumatic Diseases

Journal name in sourceAnnals of the rheumatic diseases

Journal acronymAnn Rheum Dis

Volume number50

Issue number2

Start page87

End page90

Number of pages4

ISSN0003-4967

DOIhttp://dx.doi.org/10.1136/ard.50.2.87


Abstract
Non-viable structures of Yersinia enterocolitica O:3 were shown at the site of inflammation within mononuclear cells in the synovial membrane of eight out of 10 patients with yersinia triggered reactive arthritis. An avidin-biotin-peroxidase complex method, with a rabbit antiserum specific for Y enterocolitica O:3, was used to visualise yersinia structures. All 13 control samples were negative except for one with non-specific mast cell staining. The findings emphasise the significance of foreign material in the initiation of synovitis in reactive arthritis.


Last updated on 2021-24-06 at 10:03