A1 Journal article – refereed
Objectively measured physical activity profile and cognition in Finnish elderly twins

List of Authors: Paula Iso-Markku, Katja Waller, Eero Vuoksimaa, Henri Vähä-Ypyä, Noora Lindgren, Kauko Heikkilä, Harri Sievänen, Juha Rinne, Jaakko Kaprio, Urho M. Kujala
Publisher: Elsevier Inc
Publication year: 2018
Journal name in source: Alzheimer's and Dementia: Translational Research and Clinical Interventions
Volume number: 4
ISSN: 2352-8737
eISSN: 2352-8737


Introduction: We studied whether objectively measured physical activity (PA) and sedentary behavior (SB) are associated with cognition in Finnish elderly twins.

Methods: This cross-sectional study comprised twins born in Finland from 1940 to 1944 in the Older Finnish Twin Cohort (mean age, 72.9 years; 726 persons). From 2014 to 2016, cognition was assessed with a validated telephonic interview, whereas PA was measured with a waist-worn accelerometer.

Results: In between-family models, SB and light physical activity had significant linear associations with cognition after adjusting for age, sex, wearing time, education level, body mass index, and living condition (SB: β-estimate, −0.21 [95% confidence intervals, −0.42 to −0.003]; light physical activity: β-estimate, 0.30 [95% confidence intervals, 0.02–0.58]). In within-family models, there were no significant linear associations between objectively measured PA and cognition.

Discussion: Objectively measured light physical activity and SB are associated with cognition in Finnish twins in their seventies, but the associations were attributable to genetic and environmental selection.

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Last updated on 2019-20-07 at 15:39