Refereed journal article or data article (A1)
Home-measured blood pressure is more strongly associated with electrocardiographic left ventricular hypertrophy than is clinic blood pressure: the Finn-HOME study
List of Authors: Niiranen T, Jula A, Kantola I, Karanko H, Reunanen A
Publisher: NATURE PUBLISHING GROUP
Publication year: 2007
Journal: Journal of Human Hypertension
Journal name in source: JOURNAL OF HUMAN HYPERTENSION
Journal acronym: J HUM HYPERTENS
Volume number: 21
Issue number: 10
Start page: 788
End page: 794
Number of pages: 7
ISSN: 0950-9240
DOI: http://dx.doi.org/10.1038/sj.jhh.1002192
Abstract
Electrocardiographic evidence of left ventricular hypertrophy (ECG-LVH) has a grave prognostic significance in hypertensive patients. The purpose of our study was to assess whether ECG-LVH is more strongly associated with home-measured blood pressure (BP) than with clinic BP, and whether the correlation between home BP and ECG-LVH increases with the number of home measurements performed. We studied a representative sample of the general adult population (1989 subjects 45-74 years of age) in Finland. Subjects included in the study underwent a clinical interview, electrocardiography and measurement of clinic BP ( mean of two clinic measurements) and home BP (mean of 14 duplicate home measurements performed during 1 week). Home BP correlated significantly better than clinic BP with the Sokolow-Lyon voltage (home/clinic systolic: r = 0.23/0.22, P = 0.60; diastolic: r = 0.17/0.12, P = 0.009), Cornell voltage (systolic: r = 0.30/0.25, P = 0.004; diastolic: r=0.21/0.12, P=0.001) and Cornell product (systolic: r= 0.30/0.24, P=0.001; diastolic r= 0.22/0.14, P=0.001) criteria of ECG-LVH. The correlation between home BP and ECG-LVH increased slightly with the number of home measurements, but even the mean of the initial two home BP measurements correlated equally well ( systolic BP), or better ( diastolic BP) with ECG-LVH than did clinic BP. In conclusion, home BP measurement allows us to obtain a large number of measurements that have a strong association with ECG-LVH. Our data support the application of home BP measurement in clinical practice.
Electrocardiographic evidence of left ventricular hypertrophy (ECG-LVH) has a grave prognostic significance in hypertensive patients. The purpose of our study was to assess whether ECG-LVH is more strongly associated with home-measured blood pressure (BP) than with clinic BP, and whether the correlation between home BP and ECG-LVH increases with the number of home measurements performed. We studied a representative sample of the general adult population (1989 subjects 45-74 years of age) in Finland. Subjects included in the study underwent a clinical interview, electrocardiography and measurement of clinic BP ( mean of two clinic measurements) and home BP (mean of 14 duplicate home measurements performed during 1 week). Home BP correlated significantly better than clinic BP with the Sokolow-Lyon voltage (home/clinic systolic: r = 0.23/0.22, P = 0.60; diastolic: r = 0.17/0.12, P = 0.009), Cornell voltage (systolic: r = 0.30/0.25, P = 0.004; diastolic: r=0.21/0.12, P=0.001) and Cornell product (systolic: r= 0.30/0.24, P=0.001; diastolic r= 0.22/0.14, P=0.001) criteria of ECG-LVH. The correlation between home BP and ECG-LVH increased slightly with the number of home measurements, but even the mean of the initial two home BP measurements correlated equally well ( systolic BP), or better ( diastolic BP) with ECG-LVH than did clinic BP. In conclusion, home BP measurement allows us to obtain a large number of measurements that have a strong association with ECG-LVH. Our data support the application of home BP measurement in clinical practice.
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