A1 Journal article – refereed
Adventures in radiosynthesis of clinical grade [68Ga]Ga-DOTA-Siglec-9




List of Authors: Meeri Käkelä, Pauliina Luoto, Tapio Viljanen, Helena Virtanen, Heidi Liljenbäck, Sirpa Jalkanen, Juhani Knuuti, Anne Roivainen, Xiang-Guo Li
Publisher: ROYAL SOC CHEMISTRY
Publication year: 2018
Journal: RSC Advances
Journal name in source: RSC ADVANCES
Journal acronym: RSC ADV
Volume number: 8
Issue number: 15
Number of pages: 6
ISSN: 2046-2069
eISSN: 2046-2069

Abstract
We finally managed to establish a protocol for generating Good Manufacturing Practice (GMP)-grade gallium-68-labelled 1,4,7,0-tetraazacyclododecane-1,4,7,10-tetraacetic acid conjugated sialic acid-binding immunoglobulin-like lectin 9 motif containing peptide ([Ga-68]Ga-DOTA-Siglec-9), the first radiopharmaceutical for positron emission tomography imaging of vascular adhesion protein 1.

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Last updated on 2019-20-07 at 04:30